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PDB: 106 件

4V4B
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Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map.
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ...
著者Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J.
登録日2004-01-06
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (11.7 Å)
主引用文献Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004
2JAB
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A designed ankyrin repeat protein evolved to picomolar affinity to Her2
分子名称: H10-2-G3
著者Zahnd, C, Wyler, E, Schwenk, J.M, Steiner, D, Lawrence, M.C, McKern, N.M, Pecorari, F, Ward, C.W, Joos, T.O, Pluckthun, A.
登録日2006-11-27
公開日2007-05-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Designed Ankyrin Repeat Protein Evolved to Picomolar Affinity to Her2
J.Mol.Biol., 369, 2007
1P4I
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Crystal Structure of scFv against peptide GCN4
分子名称: ANTIBODY VARIABLE LIGHT CHAIN, antibody variable heavy chain
著者Zahnd, C, Spinelli, S, Luginbuhl, B, Jermutus, L, Amstutz, P, Cambillau, C, Pluckthun, A.
登録日2003-04-23
公開日2004-05-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity.
J.Biol.Chem., 279, 2004
1P4B
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Three-Dimensional Structure Of a Single Chain Fv Fragment Complexed With The peptide GCN4(7P-14P).
分子名称: Antibody Variable heavy chain, Antibody Variable light chain, GCN4(7P-14P) peptide
著者Zahnd, C, Spinelli, S, Luginbuhl, B, Jermutus, L, Amstutz, P, Cambillau, C, Pluckthun, A.
登録日2003-04-22
公開日2004-05-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity.
J.Biol.Chem., 279, 2004
3K1B
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Structure of OmpF porin
分子名称: Outer membrane protein F
著者Kefala, G, Ahn, C, Krupa, M, Maslennikov, I, Kwiatkowski, W, Choe, S, Center for Structures of Membrane Proteins (CSMP)
登録日2009-09-26
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4.39 Å)
主引用文献Structures of the OmpF porin crystallized in the presence of foscholine-12.
Protein Sci., 19, 2010
3K19
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OmpF porin
分子名称: Outer membrane protein F
著者Kefala, G, Ahn, C, Krupa, M, Maslennikov, I, Kwiatkowski, W, Choe, S, Center for Structures of Membrane Proteins (CSMP)
登録日2009-09-26
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.79 Å)
主引用文献Structures of the OmpF porin crystallized in the presence of foscholine-12.
Protein Sci., 19, 2010
3U2G
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Crystal structure of the C-terminal DUF1608 domain of the Methanosarcina acetivorans S-layer (MA0829) protein
分子名称: AMMONIUM ION, CITRIC ACID, GLYCEROL, ...
著者Chan, S, Phan, T, Ahn, C.J, Shin, A, Rohlin, L, Gunsalus, R.P, Arbing, M.A.
登録日2011-10-03
公開日2012-07-04
最終更新日2012-08-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the surface layer of the methanogenic archaean Methanosarcina acetivorans.
Proc.Natl.Acad.Sci.USA, 109, 2012
3U2H
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Crystal structure of the C-terminal DUF1608 domain of the Methanosarcina acetivorans S-layer (MA0829) protein
分子名称: GLYCEROL, S-layer protein MA0829
著者Chan, S, Phan, T, Ahn, C.J, Shin, A, Rohlin, L, Gunsalus, R.P, Arbing, M.A.
登録日2011-10-03
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structure of the surface layer of the methanogenic archaean Methanosarcina acetivorans.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GZR
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Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP (Rv2346c-Rv2347c) complex in space group C2221
分子名称: ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION
著者Arbing, M.A, Chan, S, He, Q, Harris, L, Zhou, T.T, Kuo, E, Ahn, C.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
登録日2012-09-06
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.553 Å)
主引用文献Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
3OGI
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Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP complex (Rv2346c-Rv2347c)
分子名称: Putative ESAT-6-like protein 6, Putative ESAT-6-like protein 7
著者Arbing, M.A, Chan, S, Zhou, T.T, Ahn, C, Harris, L, Kuo, E, Sawaya, M.R, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC)
登録日2010-08-16
公開日2010-08-25
最終更新日2014-05-21
実験手法X-RAY DIFFRACTION (2.549 Å)
主引用文献Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
3Q4H
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Crystal structure of the Mycobacterium smegmatis EsxGH complex (MSMEG_0620-MSMEG_0621)
分子名称: Low molecular weight protein antigen 7, Pe family protein
著者Chan, S, Harris, L, Kuo, E, Ahn, C, Zhou, T.T, Nguyen, L, Shin, A, Sawaya, M.R, Cascio, D, Arbing, M.A, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC)
登録日2010-12-23
公開日2011-01-26
最終更新日2014-05-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
4V5N
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tRNA translocation on the 70S ribosome: the post- translocational translocation intermediate TI(POST)
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T.
登録日2010-10-21
公開日2014-07-09
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
4V6T
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Structure of the bacterial ribosome complexed by tmRNA-SmpB and EF-G during translocation and MLD-loading
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Ramrath, D.J.F, Yamamoto, H, Rother, K, Wittek, D, Pech, M, Mielke, T, Loerke, J, Scheerer, P, Ivanov, P, Teraoka, Y, Shpanchenko, O, Nierhaus, K.H, Spahn, C.M.T.
登録日2012-01-27
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (8.3 Å)
主引用文献The complex of tmRNA-SmpB and EF-G on translocating ribosomes.
Nature, 485, 2012
4V7B
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Visualization of two tRNAs trapped in transit during EF-G-mediated translocation
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Ramrath, D.J.F, Lancaster, L, Sprink, T, Mielke, T, Loerke, J, Noller, H.F, Spahn, C.M.T.
登録日2013-10-27
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation.
Proc.Natl.Acad.Sci.USA, 110, 2013
2IX8
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MODEL FOR EEF3 BOUND TO AN 80S RIBOSOME
分子名称: ELONGATION FACTOR 3A
著者Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R.
登録日2006-07-07
公開日2007-07-10
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
1T1O
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Components of the control 70S ribosome to provide reference for the RRF binding site
分子名称: 19-mer fragment of the 23S rRNA, 42-mer fragment of double helix from 16S rRNA, dodecamer fragment of double helix from 23S rRNA
著者Agrawal, R.K, Sharma, M.R, Kiel, M.C, Hirokawa, G, Booth, T.M, Spahn, C.M, Grassucci, R.A, Kaji, A, Frank, J.
登録日2004-04-16
公開日2004-06-15
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications
Proc.Natl.Acad.Sci.USA, 101, 2004
6YGC
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Crystal structure of the NatC complex bound to Arl3 peptide and CoA
分子名称: ADP-ribosylation factor-like protein 3, CHLORIDE ION, COENZYME A, ...
著者Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O.
登録日2020-03-27
公開日2020-10-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.994 Å)
主引用文献Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Nat Commun, 11, 2020
6YGB
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Crystal structure of the NatC complex bound to CoA
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ...
著者Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O.
登録日2020-03-27
公開日2020-10-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.451 Å)
主引用文献Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Nat Commun, 11, 2020
6YGA
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Crystal structure of the apo NatC complex
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O.
登録日2020-03-27
公開日2020-10-28
最終更新日2020-11-18
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Nat Commun, 11, 2020
6YGD
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Crystal structure of the NatC complex bound to Gag peptide and CoA
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ...
著者Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O.
登録日2020-03-27
公開日2020-10-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.752 Å)
主引用文献Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Nat Commun, 11, 2020
4UJE
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Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement
分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S RIBOSOMAL PROTEIN S10, ...
著者Budkevich, T.V, Giesebrecht, J, Behrmann, E, Loerke, J, Ramrath, D.J.F, Mielke, T, Ismer, J, Hildebrand, P, Tung, C.-S, Nierhaus, K.H, Sanbonmatsu, K.Y, Spahn, C.M.T.
登録日2014-04-05
公開日2014-07-16
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4UJD
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mammalian 80S HCV-IRES initiation complex with eIF5B PRE-like state
分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S RIBOSOMAL PROTEIN ES1, ...
著者Yamamoto, H, Unbehaun, A, Loerke, J, Behrmann, E, Marianne, C, Burger, J, Mielke, T, Spahn, C.M.T.
登録日2014-06-18
公開日2014-07-30
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (8.9 Å)
主引用文献Structure of the Mammalian 80S Initiation Complex with Eif5B on Hcv Ires
Nat.Struct.Mol.Biol., 21, 2014
4UJC
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mammalian 80S HCV-IRES initiation complex with eIF5B POST-like state
分子名称: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES1, ...
著者Yamamoto, H, Unbehaun, A, Loerke, J, Behrmann, E, Marianne, C, Burger, J, Mielke, T, Spahn, C.M.T.
登録日2014-06-18
公開日2014-07-30
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (9.5 Å)
主引用文献Structure of the Mammalian 80S Initiation Complex with Initiation Factor 5B on Hcv-Ires RNA.
Nat.Struct.Mol.Biol., 21, 2014
4V68
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T. thermophilus 70S ribosome in complex with mRNA, tRNAs and EF-Tu.GDP.kirromycin ternary complex, fitted to a 6.4 A Cryo-EM map.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Schuette, J.-C, Spahn, C.M.T.
登録日2008-12-11
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献GTPase activation of elongation factor EF-Tu by the ribosome during decoding
Embo J., 28, 2009
4V5M
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tRNA tranlocation on the 70S ribosome: the pre-translocational translocation intermediate TI(PRE)
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T.
登録日2010-10-01
公開日2014-07-09
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010

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