4V4B
| Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map. | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ... | 著者 | Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J. | 登録日 | 2004-01-06 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (11.7 Å) | 主引用文献 | Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. Embo J., 23, 2004
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1P4I
| Crystal Structure of scFv against peptide GCN4 | 分子名称: | ANTIBODY VARIABLE LIGHT CHAIN, antibody variable heavy chain | 著者 | Zahnd, C, Spinelli, S, Luginbuhl, B, Jermutus, L, Amstutz, P, Cambillau, C, Pluckthun, A. | 登録日 | 2003-04-23 | 公開日 | 2004-05-04 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity. J.Biol.Chem., 279, 2004
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1P4B
| Three-Dimensional Structure Of a Single Chain Fv Fragment Complexed With The peptide GCN4(7P-14P). | 分子名称: | Antibody Variable heavy chain, Antibody Variable light chain, GCN4(7P-14P) peptide | 著者 | Zahnd, C, Spinelli, S, Luginbuhl, B, Jermutus, L, Amstutz, P, Cambillau, C, Pluckthun, A. | 登録日 | 2003-04-22 | 公開日 | 2004-05-04 | 最終更新日 | 2024-11-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity. J.Biol.Chem., 279, 2004
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2JAB
| A designed ankyrin repeat protein evolved to picomolar affinity to Her2 | 分子名称: | H10-2-G3 | 著者 | Zahnd, C, Wyler, E, Schwenk, J.M, Steiner, D, Lawrence, M.C, McKern, N.M, Pecorari, F, Ward, C.W, Joos, T.O, Pluckthun, A. | 登録日 | 2006-11-27 | 公開日 | 2007-05-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A Designed Ankyrin Repeat Protein Evolved to Picomolar Affinity to Her2 J.Mol.Biol., 369, 2007
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3U2H
| Crystal structure of the C-terminal DUF1608 domain of the Methanosarcina acetivorans S-layer (MA0829) protein | 分子名称: | GLYCEROL, S-layer protein MA0829 | 著者 | Chan, S, Phan, T, Ahn, C.J, Shin, A, Rohlin, L, Gunsalus, R.P, Arbing, M.A. | 登録日 | 2011-10-03 | 公開日 | 2012-07-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structure of the surface layer of the methanogenic archaean Methanosarcina acetivorans. Proc.Natl.Acad.Sci.USA, 109, 2012
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3K1B
| Structure of OmpF porin | 分子名称: | Outer membrane protein F | 著者 | Kefala, G, Ahn, C, Krupa, M, Maslennikov, I, Kwiatkowski, W, Choe, S, Center for Structures of Membrane Proteins (CSMP) | 登録日 | 2009-09-26 | 公開日 | 2010-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (4.39 Å) | 主引用文献 | Structures of the OmpF porin crystallized in the presence of foscholine-12. Protein Sci., 19, 2010
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3U2G
| Crystal structure of the C-terminal DUF1608 domain of the Methanosarcina acetivorans S-layer (MA0829) protein | 分子名称: | AMMONIUM ION, CITRIC ACID, GLYCEROL, ... | 著者 | Chan, S, Phan, T, Ahn, C.J, Shin, A, Rohlin, L, Gunsalus, R.P, Arbing, M.A. | 登録日 | 2011-10-03 | 公開日 | 2012-07-04 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the surface layer of the methanogenic archaean Methanosarcina acetivorans. Proc.Natl.Acad.Sci.USA, 109, 2012
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3OGI
| Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP complex (Rv2346c-Rv2347c) | 分子名称: | Putative ESAT-6-like protein 6, Putative ESAT-6-like protein 7 | 著者 | Arbing, M.A, Chan, S, Zhou, T.T, Ahn, C, Harris, L, Kuo, E, Sawaya, M.R, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-08-16 | 公開日 | 2010-08-25 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.549 Å) | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
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3K19
| OmpF porin | 分子名称: | Outer membrane protein F | 著者 | Kefala, G, Ahn, C, Krupa, M, Maslennikov, I, Kwiatkowski, W, Choe, S, Center for Structures of Membrane Proteins (CSMP) | 登録日 | 2009-09-26 | 公開日 | 2010-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.79 Å) | 主引用文献 | Structures of the OmpF porin crystallized in the presence of foscholine-12. Protein Sci., 19, 2010
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3Q4H
| Crystal structure of the Mycobacterium smegmatis EsxGH complex (MSMEG_0620-MSMEG_0621) | 分子名称: | Low molecular weight protein antigen 7, Pe family protein | 著者 | Chan, S, Harris, L, Kuo, E, Ahn, C, Zhou, T.T, Nguyen, L, Shin, A, Sawaya, M.R, Cascio, D, Arbing, M.A, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-12-23 | 公開日 | 2011-01-26 | 最終更新日 | 2014-05-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
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4GZR
| Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP (Rv2346c-Rv2347c) complex in space group C2221 | 分子名称: | ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION | 著者 | Arbing, M.A, Chan, S, He, Q, Harris, L, Zhou, T.T, Kuo, E, Ahn, C.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI) | 登録日 | 2012-09-06 | 公開日 | 2012-09-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.553 Å) | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
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4V6T
| Structure of the bacterial ribosome complexed by tmRNA-SmpB and EF-G during translocation and MLD-loading | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Ramrath, D.J.F, Yamamoto, H, Rother, K, Wittek, D, Pech, M, Mielke, T, Loerke, J, Scheerer, P, Ivanov, P, Teraoka, Y, Shpanchenko, O, Nierhaus, K.H, Spahn, C.M.T. | 登録日 | 2012-01-27 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | 主引用文献 | The complex of tmRNA-SmpB and EF-G on translocating ribosomes. Nature, 485, 2012
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4V7B
| Visualization of two tRNAs trapped in transit during EF-G-mediated translocation | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Ramrath, D.J.F, Lancaster, L, Sprink, T, Mielke, T, Loerke, J, Noller, H.F, Spahn, C.M.T. | 登録日 | 2013-10-27 | 公開日 | 2014-07-09 | 最終更新日 | 2024-11-20 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation. Proc.Natl.Acad.Sci.USA, 110, 2013
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1HLY
| SOLUTION STRUCTURE OF HONGOTOXIN 1 | 分子名称: | HONGOTOXIN 1 | 著者 | Pragl, B, Koschak, A, Trieb, M, Obermair, G, Kaufmann, W.A, Gerster, U, Blanc, E, Hahn, C, Prinz, H, Schutz, G, Darbon, H, Gruber, H.J, Knaus, H.G. | 登録日 | 2000-12-04 | 公開日 | 2003-09-30 | 最終更新日 | 2024-11-06 | 実験手法 | SOLUTION NMR | 主引用文献 | Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The
first high affinity fluorescence probes for voltage-gated K+ channels. BIOCONJUG.CHEM., 13, 2002
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8BEV
| Cryo-EM structure of SARS-CoV-2 spike (HexaPro variant) in complex with nanobody W25 (map 3, focus refinement on RBD, W25 and adjacent NTD) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lauer, S, Spahn, C.M.T, Schwefel, D. | 登録日 | 2022-10-21 | 公開日 | 2023-03-08 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (5.92 Å) | 主引用文献 | Cryo-EM structure of SARS-CoV-2 spike (HexaPro variant) in complex with nanobody W25 (map 3, focus refinement on RBD, W25 and adjacent NTD) To Be Published
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8BGG
| Cryo-EM structure of SARS-CoV-2 spike (Omicron BA.1 variant) in complex with nanobody W25 (map 5, focus refinement on RBD, W25 and adjacent NTD) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody W25, Spike glycoprotein, ... | 著者 | Modhiran, N, Lauer, S, Spahn, C.M.T, Watterson, D, Schwefel, D. | 登録日 | 2022-10-27 | 公開日 | 2023-03-08 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (6.04 Å) | 主引用文献 | Cryo-EM structure of SARS-CoV-2 spike (Omicron BA.1 variant) in complex with nanobody W25 (map 5, focus refinement on RBD, W25 and adjacent NTD) To Be Published
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8AUV
| Cryo-EM structure of the plant 40S subunit | 分子名称: | 18S rRNA, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | 登録日 | 2022-08-25 | 公開日 | 2023-06-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | 主引用文献 | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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3JCN
| Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association: Initiation Complex I | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T. | 登録日 | 2016-01-04 | 公開日 | 2016-03-09 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association. Sci Adv, 2, 2016
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6YGA
| Crystal structure of the apo NatC complex | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | 登録日 | 2020-03-27 | 公開日 | 2020-10-28 | 最終更新日 | 2024-11-20 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
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6YGC
| Crystal structure of the NatC complex bound to Arl3 peptide and CoA | 分子名称: | ADP-ribosylation factor-like protein 3, CHLORIDE ION, COENZYME A, ... | 著者 | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | 登録日 | 2020-03-27 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.994 Å) | 主引用文献 | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
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8B2L
| Cryo-EM structure of the plant 80S ribosome | 分子名称: | 18S rRNA, 25S rRNA, 30S ribosomal protein S15, ... | 著者 | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | 登録日 | 2022-09-14 | 公開日 | 2023-08-23 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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6YGB
| Crystal structure of the NatC complex bound to CoA | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... | 著者 | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | 登録日 | 2020-03-27 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.451 Å) | 主引用文献 | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
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6YGD
| Crystal structure of the NatC complex bound to Gag peptide and CoA | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... | 著者 | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | 登録日 | 2020-03-27 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.752 Å) | 主引用文献 | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
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8AZW
| Cryo-EM structure of the plant 60S subunit | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | 登録日 | 2022-09-06 | 公開日 | 2023-06-07 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.14 Å) | 主引用文献 | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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4UJE
| Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement | 分子名称: | 18S Ribosomal RNA, 28S Ribosomal RNA, 40S RIBOSOMAL PROTEIN S10, ... | 著者 | Budkevich, T.V, Giesebrecht, J, Behrmann, E, Loerke, J, Ramrath, D.J.F, Mielke, T, Ismer, J, Hildebrand, P, Tung, C.-S, Nierhaus, K.H, Sanbonmatsu, K.Y, Spahn, C.M.T. | 登録日 | 2014-04-05 | 公開日 | 2014-07-16 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement. Cell(Cambridge,Mass.), 158, 2014
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