1P4I

Crystal Structure of scFv against peptide GCN4

Summary for 1P4I

• Entry DOI: 10.2210/pdb1p4i/pdb
• Related: 1P4B
• Descriptor: ANTIBODY VARIABLE LIGHT CHAIN, antibody variable heavy chain (3 entities in total)
• Functional Keywords: peptide binder, scfv, picomolar binder, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 26781.28

Authors

Zahnd, C.,Spinelli, S.,Luginbuhl, B.,Jermutus, L.,Amstutz, P.,Cambillau, C.,Pluckthun, A. (deposition date: 2003-04-23, release date: 2004-05-04, Last modification date: 2023-08-16)

• Primary citation: Zahnd, C.,Spinelli, S.,Amstutz, P.,Cambillau, C.,Pluckthun, A.; Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity.; J.Biol.Chem., 279:18870-18877, 2004; PubMed: 14754898; DOI: 10.1074/jbc.M309169200

Experimental method

X-RAY DIFFRACTION (2.8 Å)