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PDB: 230 件
4NI5
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BU of 4ni5 by Molmil
Crystal Structure of a Short Chain Dehydrogenase from Brucella suis
分子名称: MAGNESIUM ION, Oxidoreductase, short-chain dehydrogenase/reductase family protein
著者Dranow, D.M, Abendroth, J, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-11-05
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of a Short Chain Dehydrogenase from Brucella suis
TO BE PUBLISHED
5OL9
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BU of 5ol9 by Molmil
Structure of human mitochondrial transcription elongation factor (TEFM) N-terminal domain
分子名称: ACETATE ION, Transcription elongation factor, mitochondrial
著者Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D.
登録日2017-07-27
公開日2017-10-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.302 Å)
主引用文献Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
4CP3
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BU of 4cp3 by Molmil
The structure of BCL6 BTB (POZ) domain in complex with the ansamycin antibiotic rifabutin.
分子名称: B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN
著者Evans, S.E, Fairall, L, Goult, B.T, Jamieson, A.G, Ferrigno, P.K, Ford, R, Wagner, S.D, Schwabe, J.W.R.
登録日2014-01-31
公開日2014-03-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
Plos One, 9, 2014
4DGQ
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BU of 4dgq by Molmil
Crystal structure of Non-heme chloroperoxidase from Burkholderia cenocepacia
分子名称: 1,2-ETHANEDIOL, Non-heme chloroperoxidase
著者Gardberg, A.S, Edwards, T.E, Abendroth, J.A, Staker, B, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-01-26
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of Non-heme chloroperoxidase from Burkholderia cenocepacia
To be Published
2XTC
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BU of 2xtc by Molmil
Structure of the TBL1 tetramerisation domain
分子名称: F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
著者Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
登録日2010-10-06
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTE
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BU of 2xte by Molmil
Structure of the TBL1 tetramerisation domain
分子名称: F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
著者Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
登録日2010-10-06
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTD
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BU of 2xtd by Molmil
Structure of the TBL1 tetramerisation domain
分子名称: TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
著者Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
登録日2010-10-06
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
6MWE
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BU of 6mwe by Molmil
CRYSTAL STRUCTURE OF TIE2 IN COMPLEX WITH DECIPERA COMPOUND DP1919
分子名称: 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, Angiopoietin-1 receptor, SULFATE ION
著者Chun, L, Abendroth, J, Edwards, T.E.
登録日2018-10-29
公開日2018-11-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2
Mol. Cancer Ther., 16, 2017
4PFZ
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BU of 4pfz by Molmil
X-ray Crystal Structure of 5-carboxymethyl-2-hydroxymuconate delta-isomerase from Mycobacterium smegmatis
分子名称: 5-carboxymethyl-2-hydroxymuconate delta-isomerase, SODIUM ION
著者Horanyi, P.S, Abendroth, J, Lorimer, D, Edwards, T, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-05-01
公開日2014-11-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray Crystal Structure of 5-carboxymethyl-2-hydroxymuconate delta-isomerase from Mycobacterium smegmatis
To Be Published
1HV8
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BU of 1hv8 by Molmil
CRYSTAL STRUCTURE OF A DEAD BOX PROTEIN FROM THE HYPERTHERMOPHILE METHANOCOCCUS JANNASCHII
分子名称: PUTATIVE ATP-DEPENDENT RNA HELICASE MJ0669, SULFATE ION
著者Story, R.M, Li, H, Abelson, J.N.
登録日2001-01-08
公開日2001-02-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a DEAD box protein from the hyperthermophile Methanococcus jannaschii.
Proc.Natl.Acad.Sci.USA, 98, 2001
2L5G
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BU of 2l5g by Molmil
Co-ordinates and 1H, 13C and 15N chemical shift assignments for the complex of GPS2 53-90 and SMRT 167-207
分子名称: G protein pathway suppressor 2, Putative uncharacterized protein NCOR2
著者Oberoi, J, Yang, J, Neuhaus, D, Schwabe, J.W.R.
登録日2010-11-01
公開日2011-02-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.
Nat.Struct.Mol.Biol., 18, 2011
2YHO
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BU of 2yho by Molmil
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
分子名称: ACETATE ION, E3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ...
著者Fairall, L, Goult, B.T, Millard, C.J, Tontonoz, P, Schwabe, J.W.R.
登録日2011-05-04
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
6MOB
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BU of 6mob by Molmil
Crystal structure of KIT1 in complex with DP2976 via co-crystallization
分子名称: Mast/stem cell growth factor receptor Kit, N-{4-chloro-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl}-N'-phenylurea, NITRATE ION
著者Edwards, T.E, Abendroth, J, Safford, K, Chun, L.
登録日2018-10-04
公開日2019-07-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants.
Cancer Cell, 35, 2019
2YHN
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BU of 2yhn by Molmil
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
分子名称: E3 UBIQUITIN-PROTEIN LIGASE MYLIP, ZINC ION
著者Fairall, L, Goult, B.T, Millard, C.J, Tontonoz, P, Schwabe, J.W.R.
登録日2011-05-04
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
2Z6K
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BU of 2z6k by Molmil
Crystal structure of full-length human RPA14/32 heterodimer
分子名称: Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit
著者Deng, X, Habel, J.E, Kabaleeswaran, V, Borgstahl, G.E.
登録日2007-08-03
公開日2007-12-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the Full-length Human RPA14/32 Complex Gives Insights into the Mechanism of DNA Binding and Complex Formation
J.Mol.Biol., 374, 2007
3U0B
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BU of 3u0b by Molmil
Crystal structure of an oxidoreductase from Mycobacterium smegmatis
分子名称: Oxidoreductase, short chain dehydrogenase/reductase family protein, SODIUM ION
著者Arakaki, T.L, Staker, B.L, Clifton, M.C, Abendroth, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-09-28
公開日2011-10-05
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and functional characterization of FabG4 from Mycolicibacterium smegmatis.
Acta Crystallogr.,Sect.F, 80, 2024
3SDS
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BU of 3sds by Molmil
Crystal structure of a mitochondrial ornithine carbamoyltransferase from Coccidioides immitis
分子名称: CHLORIDE ION, Ornithine carbamoyltransferase, mitochondrial
著者Edwards, T.E, Abendroth, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-06-09
公開日2011-06-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline.
Acta Crystallogr.,Sect.F, 67, 2011
3UWA
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BU of 3uwa by Molmil
Crystal structure of a probable peptide deformylase from synechococcus phage S-SSM7
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, RIIA-RIIB membrane-associated protein, ZINC ION
著者Lorimer, D, Abendroth, J, Edwards, T.E, Burgin, A, Segall, A, Rohwer, F.
登録日2011-12-01
公開日2013-01-09
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and function of a cyanophage-encoded peptide deformylase.
ISME J, 7, 2013
3UWB
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BU of 3uwb by Molmil
Crystal structure of a probable peptide deformylase from strucynechococcus phage S-SSM7 in complex with actinonin
分子名称: 1,2-ETHANEDIOL, ACTINONIN, CHLORIDE ION, ...
著者Lorimer, D, Abendroth, J, Edwards, T.E, Burgin, A, Segall, A, Rohwer, F.
登録日2011-12-01
公開日2013-01-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and function of a cyanophage-encoded peptide deformylase.
ISME J, 7, 2013
3SI9
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BU of 3si9 by Molmil
Crystal structure of Dihydrodipicolinate Synthase from Bartonella Henselae
分子名称: 1,2-ETHANEDIOL, Dihydrodipicolinate synthase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID), Staker, B.L, Abendroth, J, Sankaran, B.
登録日2011-06-17
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cloning, expression, purification, crystallization and X-ray diffraction analysis of dihydrodipicolinate synthase from the human pathogenic bacterium Bartonella henselae strain Houston-1 at 2.1 angstrom resolution.
Acta Crystallogr F Struct Biol Commun, 72, 2016
2D49
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BU of 2d49 by Molmil
Solution structure of the Chitin-Binding Domain of Streptomyces griseus Chitinase C
分子名称: chitinase C
著者Akagi, K, Watanabe, J, Hara, M, Kezuka, Y, Chikaishi, E, Yamaguchi, T, Akutsu, H, Nonaka, T, Watanabe, T, Ikegami, T.
登録日2005-10-11
公開日2006-10-11
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Identification of the substrate interaction region of the chitin-binding domain of Streptomyces griseus chitinase C
J.Biochem.(Tokyo), 139, 2006
2VV4
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BU of 2vv4 by Molmil
hPPARgamma Ligand binding domain in complex with 6-oxoOTE
分子名称: (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid, (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
著者Itoh, T, Fairall, L, Schwabe, J.W.R.
登録日2008-06-02
公開日2008-08-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
2VST
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BU of 2vst by Molmil
hPPARgamma Ligand binding domain in complex with 13-(S)-HODE
分子名称: (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
著者Itoh, T, Fairall, L, Schwabe, J.W.R.
登録日2008-04-29
公開日2008-08-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
2VV3
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BU of 2vv3 by Molmil
hPPARgamma Ligand binding domain in complex with 4-oxoDHA
分子名称: (6E,10Z,13Z,16Z,19Z)-4-oxodocosa-6,10,13,16,19-pentaenoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
著者Itoh, T, Fairall, L, Schwabe, J.W.R.
登録日2008-06-02
公開日2008-08-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Basis for the Activation of Ppargamma by Oxidized Fatty Acids.
Nat.Struct.Mol.Biol., 15, 2008
2VV0
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BU of 2vv0 by Molmil
hPPARgamma Ligand binding domain in complex with DHA
分子名称: DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
著者Itoh, T, Fairall, L, Schwabe, J.W.R.
登録日2008-06-02
公開日2008-08-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008

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