6Z3A
 
 | | Mec1-Ddc2 (wild-type) in complex with AMP-PNP | | 分子名称: | DNA damage checkpoint protein LCD1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase MEC1, ... | | 著者 | Yates, L.A, Zhang, X. | | 登録日 | 2020-05-19 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Nat.Struct.Mol.Biol., 28, 2021
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2PCJ
 | | Crystal structure of ABC transporter (aq_297) From Aquifex Aeolicus VF5 | | 分子名称: | Lipoprotein-releasing system ATP-binding protein lolD, SULFITE ION | | 著者 | Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-30 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of ABC transporter (aq_297) From Aquifex Aeolicus VF5
To be Published
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6KFE
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1KAV
 | | Human Tyrosine Phosphatase 1B Complexed with an Inhibitor | | 分子名称: | PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1, [(4-{4-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-BUTYL}-PHENYL)-DIFLUORO-METHYL]-PHOSPHONIC ACID | | 著者 | Jia, Z, Ye, Q, Dinaut, A.N, Wang, Q, Waddleton, D, Payette, P, Ramachandran, C, Kennedy, B, Hum, G, Taylor, S.D. | | 登録日 | 2001-11-03 | | 公開日 | 2002-06-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.
J.Med.Chem., 44, 2001
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6E8W
 | | MPER-TM Domain of HIV-1 envelope glycoprotein (Env) | | 分子名称: | Envelope glycoprotein gp160 | | 著者 | Fu, Q, Shaik, M.M, Cai, Y, Ghantous, F, Piai, A, Peng, H, Rits-Volloch, S, Liu, Z, Harrison, S.C, Seaman, M.S, Chen, B, Chou, J.J. | | 登録日 | 2018-07-31 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the membrane proximal external region of HIV-1 envelope glycoprotein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6QQA
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6QQB
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3AEF
 | | Crystal structure of porcine heart mitochondrial complex II with an empty quinone-binding pocket | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K. | | 登録日 | 2010-02-04 | | 公開日 | 2011-02-09 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of porcine heart mitochondrial complex II with an empty quinone-binding pocket
To be Published
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6EPI
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1U5S
 | | NMR structure of the complex between Nck-2 SH3 domain and PINCH-1 LIM4 domain | | 分子名称: | Cytoplasmic protein NCK2, PINCH protein, ZINC ION | | 著者 | Vaynberg, J, Fukuda, T, Vinogradova, O, Velyvis, A, Ng, L, Wu, C, Qin, J. | | 登録日 | 2004-07-28 | | 公開日 | 2005-04-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility.
Mol.Cell, 17, 2005
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6EBR
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1U74
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8BI5
 | | Crystal structure of human Choline Kinase A in complex with UNC0737 | | 分子名称: | 1,2-ETHANEDIOL, 2-cyclohexyl-6-methoxy-~{N}-methyl-~{N}-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine, CHLORIDE ION, ... | | 著者 | Diaz-Saez, L, Ward, J, Kennedy, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Huber, K, Structural Genomics Consortium (SGC) | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of human Choline Kinase A in complex with UNC0737
To Be Published
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6ZCV
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8BI6
 | | Crystal structure of human Choline Kinase A in complex with UNC0638 | | 分子名称: | 1,2-ETHANEDIOL, 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)piperidin-4-yl]-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine, CHLORIDE ION, ... | | 著者 | Diaz-Saez, L, Ward, J, Kennedy, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Huber, K, Structural Genomics Consortium (SGC) | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of human Choline Kinase A in complex with UNC0638
To Be Published
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3A10
 | | Crystal structure of response regulator protein TrrA (TM1360) from Thermotoga maritima in complex with Mg(2+)-BeF (SeMet, L89M) | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Response regulator, ... | | 著者 | Yamada, S, Sugimoto, H, Kobayashi, M, Ohno, A, Nakamura, H, Shiro, Y. | | 登録日 | 2009-03-25 | | 公開日 | 2009-10-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Structure of PAS-linked histidine kinase and the response regulator complex
Structure, 17, 2009
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6YX5
 | | Structure of DrrA from Legionella pneumophilia in complex with human Rab8a | | 分子名称: | MAGNESIUM ION, Multifunctional virulence effector protein DrrA, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Schneider, S, Du, J, von Wrisberg, M.K, Lang, K, Itzen, A. | | 登録日 | 2020-04-30 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1.
Nat Commun, 12, 2021
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4MAP
 | | Crystal structure of Ara h 8 purified with heating | | 分子名称: | Ara h 8 allergen, SODIUM ION | | 著者 | Offermann, L.R, Hurlburt, B.K, Majorek, K.A, McBride, J.K, Maleki, S.J, Chruszcz, M. | | 登録日 | 2013-08-16 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and Function of the Peanut Panallergen Ara h 8.
J.Biol.Chem., 288, 2013
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6ZJB
 | | Crystal structure of human adenylate kinase 3, AK3, in complex with inhibitor Gp5A | | 分子名称: | GTP:AMP phosphotransferase AK3, mitochondrial, MAGNESIUM ION, ... | | 著者 | Grundstrom, C, Rogne, P, Wolf-Watz, M, Sauer-Eriksson, A.E. | | 登録日 | 2020-06-28 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.822 Å) | | 主引用文献 | Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3.
Biochemistry, 59, 2020
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6E68
 | | NAMPT co-crystal with inhibitor compound 2 | | 分子名称: | (2E)-N-{4-[1-(3-aminobenzene-1-carbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | | 著者 | Waight, A.B, Neumann, C.S. | | 登録日 | 2018-07-24 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | NAMPT co-crystal with inhibitor compound 2
to be published
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8BJM
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1K8G
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8BQ1
 | | Herpes simplex virus type 1 protease | | 分子名称: | Assemblin, GLYCEROL | | 著者 | Pachota, M, Grzywa, R, Plewka, J, Wilk, P, Mackereth, C, Czarna, A, Sienczyk, M, Pyrc, K. | | 登録日 | 2022-11-18 | | 公開日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Herpes simplex virus type 1 protease
To Be Published
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6Z2W
 | | Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP | | 分子名称: | DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Yates, L.A, Zhang, X. | | 登録日 | 2020-05-18 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Nat.Struct.Mol.Biol., 28, 2021
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1TPN
 | | SOLUTION STRUCTURE OF THE FIBRIN BINDING FINGER DOMAIN OF TISSUE-TYPE PLASMINOGEN ACTIVATOR DETERMINED BY 1H NUCLEAR MAGNETIC RESONANCE | | 分子名称: | TISSUE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Downing, A.K, Driscoll, P.C, Harvey, T.S, Dudgeon, T.J, Smith, B.O, Baron, M, Campbell, I.D. | | 登録日 | 1993-05-26 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the fibrin binding finger domain of tissue-type plasminogen activator determined by 1H nuclear magnetic resonance.
J.Mol.Biol., 225, 1992
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