8BI6
Crystal structure of human Choline Kinase A in complex with UNC0638
Summary for 8BI6
Entry DOI | 10.2210/pdb8bi6/pdb |
Descriptor | Choline kinase alpha, MAGNESIUM ION, 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)piperidin-4-yl]-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine, ... (9 entities in total) |
Functional Keywords | inhibitor, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 107253.29 |
Authors | Diaz-Saez, L.,Ward, J.,Kennedy, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Structural Genomics Consortium (SGC) (deposition date: 2022-11-01, release date: 2023-11-15) |
Primary citation | Diaz-Saez, L.,Kennedy, E.,von Delft, F.,Knapp, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K. Crystal structure of human Choline Kinase A in complex with UNC0638 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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