6ZJB
Crystal structure of human adenylate kinase 3, AK3, in complex with inhibitor Gp5A
Summary for 6ZJB
| Entry DOI | 10.2210/pdb6zjb/pdb |
| Descriptor | GTP:AMP phosphotransferase AK3, mitochondrial, P1-(5'-ADENOSYL)-P5-(5'-GUANOSYL) PENTAPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
| Functional Keywords | gtp:amp phosphotransferase, gp5a, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 6 |
| Total formula weight | 159336.37 |
| Authors | Grundstrom, C.,Rogne, P.,Wolf-Watz, M.,Sauer-Eriksson, A.E. (deposition date: 2020-06-28, release date: 2020-09-16, Last modification date: 2024-01-31) |
| Primary citation | Rogne, P.,Dulko-Smith, B.,Goodman, J.,Rosselin, M.,Grundstrom, C.,Hedberg, C.,Nam, K.,Sauer-Eriksson, A.E.,Wolf-Watz, M. Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3. Biochemistry, 59:3570-3581, 2020 Cited by PubMed: 32822537DOI: 10.1021/acs.biochem.0c00549 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.822 Å) |
Structure validation
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