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PDB: 89111 件

7SGS
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Cryo-EM structure of full-length MAP7 bound to the microtubule
分子名称: Ensconsin, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ferro, L.S, Fang, Q, Eshun-Wilson, L, Fernandes, J, Jack, A, Farrell, D.P, Golcuk, M, Huijben, T, Costa, K, Gur, M, DiMaio, F, Nogales, E, Yildiz, A.
登録日2021-10-07
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural and functional insight into regulation of kinesin-1 by microtubule-associated protein MAP7.
Science, 375, 2022
7RXA
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afTMEM16 DE/AA mutant in C14 lipid nanodiscs in the presence of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
著者Feng, Z, Accardi, A.
登録日2021-08-22
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
6BPV
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Crystal structure of cysteine-bound ferrous form of the matured F2-Tyr157 human cysteine dioxygenase
分子名称: CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ...
著者Liu, A, Li, J, Shin, I.
登録日2017-11-26
公開日2018-07-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase.
Nat. Chem. Biol., 14, 2018
7RX2
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afTMEM16 in C22 lipid nanodiscs with MSP1E3 scaffold protein in the presnece of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-21
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
4ZH7
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Structural basis of Lewisb antigen binding by the Helicobacter pylori adhesin BabA
分子名称: Outer membrane protein-adhesin, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose
著者Howard, T, Hage, N, Phillips, C, Brassington, C.A, Debreczeni, J, Overman, R, Gellert, P, Stolnik, S, Winkler, G.S, Falcone, F.H.
登録日2015-04-24
公開日2015-08-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural basis of Lewis(b) antigen binding by the Helicobacter pylori adhesin BabA.
Sci Adv, 1, 2015
6PZK
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Cryo-EM Structure of the Respiratory Syncytial Virus Polymerase (L) Protein Bound by the Tetrameric Phosphoprotein (P)
分子名称: Phosphoprotein, RNA-directed RNA polymerase L
著者Gilman, M.S.A, McLellan, J.S.
登録日2019-08-01
公開日2019-09-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the Respiratory Syncytial Virus Polymerase Complex.
Cell, 179, 2019
7RX3
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afTMEM16 in C14 lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-21
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXB
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afTMEM16 lipid scramblase in C18 lipid nanodiscs in the absence of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
著者Feng, Z, Accardi, A.
登録日2021-08-22
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
4TWC
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BU of 4twc by Molmil
2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4- carboxamide derivatives as potent inhibitors of CK1d/e
分子名称: 2-{[2-(trifluoromethoxy)benzoyl]amino}-N-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1,3-thiazole-4-carboxamide, Casein kinase I isoform delta, DIMETHYL SULFOXIDE, ...
著者Bischof, J, Leban, L, Zaja, M, Grothey, A, Radunsky, B, Othersen, O, Strobl, S, Vitt, D, Knippschild, U.
登録日2014-06-30
公開日2014-10-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1d/e.
Amino Acids, 43, 2012
7RWJ
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afTMEM16 in C22 lipid nanodiscs with MSP2N2 scaffold protein in the presnece of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Plasma membrane channel protein (Aqy1), ...
著者Falzone, M.E, Accardi, A.
登録日2021-08-20
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
5DE5
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BU of 5de5 by Molmil
Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA.
分子名称: Fragile X mental retardation protein 1, POTASSIUM ION, sc1
著者Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A.
登録日2015-08-25
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.0011 Å)
主引用文献Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP.
Proc.Natl.Acad.Sci.USA, 112, 2015
6MSY
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BU of 6msy by Molmil
Anti-HIV-1 Fab Fab 2G12 + Man4 re-refinement
分子名称: ACETATE ION, Fab 2G12, light chain, ...
著者Calarese, D.A, Stanfield, R.L, Wilson, I.A.
登録日2018-10-18
公開日2018-11-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005
6Q76
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Complex of rice blast (Magnaporthe oryzae) effector protein AVR-Pia with the HMA domain of Pikp-1 from rice (Oryza sativa)
分子名称: AVR-Pia protein, Resistance protein Pikp-1
著者Varden, F.A, Banfield, M.J.
登録日2018-12-12
公開日2019-07-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cross-reactivity of a rice NLR immune receptor to distinct effectors from the rice blast pathogenMagnaporthe oryzaeprovides partial disease resistance.
J.Biol.Chem., 294, 2019
5K7M
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BU of 5k7m by Molmil
Crystal structure of the catalytic domains of Mettl3/Mettl14 complex
分子名称: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14
著者Wang, P, Doxtader, K.A, Nam, Y.
登録日2016-05-26
公開日2016-07-06
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Mol.Cell, 63, 2016
3M6U
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BU of 3m6u by Molmil
Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus in space group 43
分子名称: SULFATE ION, rRNA methylase
著者Demirci, H, Larsen, H.G.L, Hansen, T, Rasmussen, A, Cadambi, A, Gregory, S.T, Kirpekar, F, Jogl, G.
登録日2010-03-16
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus.
Rna, 16, 2010
6HD5
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BU of 6hd5 by Molmil
Cryo-EM structure of the ribosome-NatA complex
分子名称: N-alpha-acetyltransferase NAT5, N-terminal acetyltransferase A complex catalytic subunit ARD1, N-terminal acetyltransferase A complex subunit NAT1
著者Knorr, A.G, Becker, T, Beckmann, R.
登録日2018-08-17
公開日2018-12-19
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Ribosome-NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation.
Nat. Struct. Mol. Biol., 26, 2019
5Z79
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BU of 5z79 by Molmil
Crystal Structure Analysis of the HPPK-DHPS in complex with substrates
分子名称: 4-AMINOBENZOIC ACID, 5'-DEOXYADENOSINE, 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE, ...
著者Manickam, Y, Karl, H, Sharma, A.
登録日2018-01-27
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-dihydropteroate synthase fromPlasmodium vivaxsheds light on drug resistance
J. Biol. Chem., 293, 2018
5CPT
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BU of 5cpt by Molmil
Disproportionating enzyme 1 from Arabidopsis - beta cyclodextrin soak
分子名称: 1,2-ETHANEDIOL, 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic, ...
著者O'Neill, E.C, Stevenson, C.E.M, Tantanarat, K, Latousakis, D, Donaldson, M.I, Rejzek, M, Limpaseni, T, Smith, A.M, Field, R.A, Lawson, D.M.
登録日2015-07-21
公開日2015-11-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1).
J.Biol.Chem., 290, 2015
6FXY
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BU of 6fxy by Molmil
Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Cocrystal with Fe2+, Mn2+, UDP-Gal - Structure from long-wavelength S-SAD
分子名称: 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scietti, L, Chiapparino, A, De Giorgi, F, Fumagalli, M, Khoriauli, L, Nergadze, S, Basu, S, Olieric, V, Banushi, B, Giulotto, E, Gissen, P, Forneris, F.
登録日2018-03-09
公開日2018-08-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.138 Å)
主引用文献Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6LVB
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Structure of Dimethylformamidase, tetramer
分子名称: FE (III) ION, N,N-dimethylformamidase large subunit, N,N-dimethylformamidase small subunit
著者Arya, C.A, Yadav, S, Fine, J, Casanal, A, Chopra, G, Ramanathan, G, Subramanian, R, Vinothkumar, K.R.
登録日2020-02-02
公開日2020-06-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A 2-Tyr-1-carboxylate Mononuclear Iron Center Forms the Active Site of a Paracoccus Dimethylformamidase.
Angew.Chem.Int.Ed.Engl., 59, 2020
6FZ1
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Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant L360F
分子名称: CALCIUM ION, Lipase, ZINC ION
著者Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A.
登録日2018-03-13
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol.
Appl.Environ.Microbiol., 84, 2018
3JZB
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BU of 3jzb by Molmil
Crystal Structure of TR-alfa bound to the selective thyromimetic TRIAC
分子名称: THRA protein, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID
著者Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R.
登録日2009-09-23
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.007 Å)
主引用文献Gaining ligand selectivity in thyroid hormone receptors via entropy.
Proc.Natl.Acad.Sci.USA, 106, 2009
5UF6
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BU of 5uf6 by Molmil
The 2.8 A Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparanoid Pentasaccharide
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, capsid protein VP1
著者Xie, Q, Spear, J.M, Noble, A.J, Sousa, D.R, Meyer, N.L, Davulcu, O, Zhang, F, Linhardt, R.J, Stagg, S.M, Chapman, M.
登録日2017-01-03
公開日2017-05-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The 2.8 angstrom Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide.
Mol Ther Methods Clin Dev, 5, 2017
5UFS
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X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with triamcinolone acetonide and SHP coregulator fragment
分子名称: Ancestral Glucocorticoid Receptor2, SHP NR Box 1 Peptide, Triamcinolone acetonide
著者Weikum, E.R, Ortlund, E.A.
登録日2017-01-05
公開日2017-04-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.118 Å)
主引用文献Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner.
Mol. Pharmacol., 92, 2017
6Q8W
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Respiratory complex I from Thermus thermophilus with bound Aureothin.
分子名称: Aureothin, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
著者Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A.
登録日2018-12-16
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020

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