5UFS
X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with triamcinolone acetonide and SHP coregulator fragment
Summary for 5UFS
Entry DOI | 10.2210/pdb5ufs/pdb |
Descriptor | Ancestral Glucocorticoid Receptor2, SHP NR Box 1 Peptide, Triamcinolone acetonide, ... (4 entities in total) |
Functional Keywords | nuclear receptors, glucocorticoid receptor, ligand binding domain, hormone receptor |
Biological source | unidentified More |
Total number of polymer chains | 4 |
Total formula weight | 60252.18 |
Authors | Weikum, E.R.,Ortlund, E.A. (deposition date: 2017-01-05, release date: 2017-04-26, Last modification date: 2023-10-04) |
Primary citation | Weikum, E.R.,Okafor, C.D.,D'Agostino, E.H.,Colucci, J.K.,Ortlund, E.A. Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner. Mol. Pharmacol., 92:12-21, 2017 Cited by PubMed: 28396564DOI: 10.1124/mol.117.108506 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.118 Å) |
Structure validation
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