5UFS
X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with triamcinolone acetonide and SHP coregulator fragment
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
| A | 0030518 | biological_process | nuclear receptor-mediated steroid hormone signaling pathway |
| A | 0034056 | molecular_function | estrogen response element binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
| B | 0030518 | biological_process | nuclear receptor-mediated steroid hormone signaling pathway |
| B | 0034056 | molecular_function | estrogen response element binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue 1TA A 301 |
| Chain | Residue |
| A | LEU32 |
| A | PHE204 |
| A | CYS205 |
| A | THR208 |
| A | VAL216 |
| A | PHE218 |
| A | ASN33 |
| A | GLY36 |
| A | GLN39 |
| A | MET73 |
| A | ARG80 |
| A | PHE92 |
| A | TYR107 |
| A | GLN111 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue 1TA B 301 |
| Chain | Residue |
| B | LEU32 |
| B | ASN33 |
| B | GLY36 |
| B | GLN39 |
| B | MET73 |
| B | ARG80 |
| B | PHE92 |
| B | TYR107 |
| B | GLN111 |
| B | PHE204 |
| B | CYS205 |
| B | THR208 |
| B | VAL216 |
| B | PHE218 |
