2OJU
 
 | |
2OK3
 | | X-ray structure of human cyclophilin J at 2.0 angstrom | | 分子名称: | NICKEL (II) ION, Peptidyl-prolyl cis-trans isomerase-like 3 | | 著者 | Xia, Z. | | 登録日 | 2007-01-15 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Targeting Cyclophilin J, a novel peptidyl-prolyl isomerase, can induce cellular G1/S arrest and repress the growth of Hepatocellular carcinoma
To be Published
|
|
7JY5
 | | Structure of human p97 in complex with ATPgammaS and Npl4/Ufd1 (masked around p97) | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | | 登録日 | 2020-08-28 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative.
Nat Commun, 12, 2021
|
|
7LAQ
 | |
7LAM
 | | Crystal structure of Campylobacter jejuni Cj0843c lytic transglycosylase in complex with N,N',N''-triacetylchitotriose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CITRIC ACID, ... | | 著者 | van den Akker, F, Kumar, V. | | 登録日 | 2021-01-06 | | 公開日 | 2021-04-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Turnover Chemistry and Structural Characterization of the Cj0843c Lytic Transglycosylase of Campylobacter jejuni .
Biochemistry, 60, 2021
|
|
6CFC
 | |
6CF8
 | |
6CF9
 | |
7RWK
 | | Structure of Cap5 from Asticcacaulis sp. | | 分子名称: | MAGNESIUM ION, SAVED domain-containing protein, ZINC ION | | 著者 | Huang, R.H, Fatma, S, Chakravarti, A. | | 登録日 | 2021-08-20 | | 公開日 | 2021-11-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Molecular mechanisms of the CdnG-Cap5 antiphage defense system employing 3',2'-cGAMP as the second messenger.
Nat Commun, 12, 2021
|
|
7RWM
 | |
7RWS
 | |
8URN
 | | Crystal structure of EscI(51-87)-linker-EtgA(18-152) fusion protein | | 分子名称: | EscI inner rod protein type III secretion system,EtgA protein, SULFATE ION | | 著者 | van den Akker, F. | | 登録日 | 2023-10-26 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural insights into peptidoglycan glycosidase EtgA binding to the inner rod protein EscI of the type III secretion system via a designed EscI-EtgA fusion protein.
Protein Sci., 33, 2024
|
|
4GL2
 | | Structural Basis for dsRNA duplex backbone recognition by MDA5 | | 分子名称: | Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(*AP*UP*CP*CP*GP*CP*GP*GP*CP*CP*CP*U)-3'), ... | | 著者 | Wu, B, Hur, S. | | 登録日 | 2012-08-13 | | 公開日 | 2013-01-09 | | 最終更新日 | 2013-02-06 | | 実験手法 | X-RAY DIFFRACTION (3.557 Å) | | 主引用文献 | Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5.
Cell(Cambridge,Mass.), 152, 2013
|
|
6OAP
 | | Crystal structure of a dual sensor histidine kinase in the green-light absorbing Pg state | | 分子名称: | Dual sensor histidine kinase, MAGNESIUM ION, PHYCOCYANOBILIN | | 著者 | Heewhan, S, Zhong, R, Xiaoli, Z, Sepalika, B, Xiaojing, Y. | | 登録日 | 2019-03-18 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural basis of molecular logic OR in a dual-sensor histidine kinase.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
7CJF
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... | | 著者 | Guo, Y, Li, X, Zhang, G, Fu, D, Schweizer, L, Zhang, H, Rao, Z. | | 登録日 | 2020-07-10 | | 公開日 | 2020-11-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.108 Å) | | 主引用文献 | A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes.
Nat Commun, 12, 2021
|
|
2I1T
 | |
7CVQ
 | |
7CVO
 | |
7DCN
 | |
7DCM
 | | Crystal structure of CITX | | 分子名称: | Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, ZINC ION | | 著者 | Xu, H, Wang, B, Su, X.D. | | 登録日 | 2020-10-26 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-05-17 | | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | | 主引用文献 | Co-evolution-based prediction of metal-binding sites in proteomes by machine learning.
Nat.Chem.Biol., 19, 2023
|
|
7DG4
 | |
7DHN
 | | The co-crystal structure of DYRK2 with a small molecule inhibitor 20 | | 分子名称: | 7-methoxy-2-methylsulfanyl-9-(piperidin-4-ylmethylsulfanyl)-[1,3]thiazolo[5,4-b]quinoline, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | | 著者 | Wei, T, Xiao, J. | | 登録日 | 2020-11-16 | | 公開日 | 2021-11-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry.
Elife, 11, 2022
|
|
7DHO
 | | The co-crystal structure of DYRK2 with a small molecule inhibitor 14 | | 分子名称: | 2-methoxy-9-(piperidin-4-ylmethylsulfanyl)-7-propan-2-yloxy-acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | | 著者 | Wei, T, Xiao, J. | | 登録日 | 2020-11-16 | | 公開日 | 2021-11-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry.
Elife, 11, 2022
|
|
7DH9
 | | The co-crystal structure of DYRK2 with a small molecule inhibitor 7 | | 分子名称: | Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridin-4-yl]methanol | | 著者 | Wei, T, Xiao, J. | | 登録日 | 2020-11-13 | | 公開日 | 2021-11-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry.
Elife, 11, 2022
|
|
7DJO
 | | The co-crystal structure of DYRK2 with a small molecule inhibitor 17 | | 分子名称: | Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol | | 著者 | Wei, T, Xiao, J. | | 登録日 | 2020-11-20 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry.
Elife, 11, 2022
|
|
