1DUJ
| SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2 | Descriptor: | SPINDLE ASSEMBLY CHECKPOINT PROTEIN | Authors: | Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H. | Deposit date: | 2000-01-17 | Release date: | 2000-03-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nat.Struct.Biol., 7, 2000
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3GMH
| Crystal Structure of the Mad2 Dimer | Descriptor: | Mitotic spindle assembly checkpoint protein MAD2A, SULFATE ION | Authors: | Ozkan, E, Luo, X, Machius, M, Yu, H, Deisenhofer, J. | Deposit date: | 2009-03-13 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.95 Å) | Cite: | Structure of an intermediate conformer of the spindle checkpoint protein Mad2. Proc.Natl.Acad.Sci.USA, 112, 2015
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5UN0
| Crystal Structure of Mycobacterium Tuberculosis Proteasome-assembly chaperone homologue Rv2125 | Descriptor: | proteasome assembly chaperone 2 (PAC2) homologue Rv2125 | Authors: | Bai, L, Jastrab, J.B, Hu, K, Yu, H, Darwin, K.H, Li, H. | Deposit date: | 2017-01-30 | Release date: | 2017-03-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Analysis of Mycobacterium tuberculosis Homologues of the Eukaryotic Proteasome Assembly Chaperone 2 (PAC2). J. Bacteriol., 199, 2017
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6OCF
| The crystal structure of VASH1-SVBP complex | Descriptor: | CHLORIDE ION, GLYCEROL, Small vasohibin-binding protein, ... | Authors: | Li, F, Luo, X, Yu, H. | Deposit date: | 2019-03-23 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Structural basis of tubulin detyrosination by vasohibins. Nat.Struct.Mol.Biol., 26, 2019
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6OCH
| Crystal structure of VASH1-SVBP complex bound with parthenolide | Descriptor: | GLYCEROL, SULFATE ION, Small vasohibin-binding protein, ... | Authors: | Li, F, Luo, X, Yu, H. | Deposit date: | 2019-03-23 | Release date: | 2019-06-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Structural basis of tubulin detyrosination by vasohibins. Nat.Struct.Mol.Biol., 26, 2019
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4K6J
| Human cohesin inhibitor WapL | Descriptor: | ACETATE ION, SULFATE ION, Wings apart-like protein homolog | Authors: | Tomchick, D.R, Yu, H, Ouyang, Z. | Deposit date: | 2013-04-16 | Release date: | 2013-06-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6205 Å) | Cite: | Structure of the human cohesin inhibitor Wapl. Proc.Natl.Acad.Sci.USA, 110, 2013
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1KLQ
| The Mad2 Spindle Checkpoint Protein Undergoes Similar Major Conformational Changes upon Binding to Either Mad1 or Cdc20 | Descriptor: | MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, Mad2-binding peptide | Authors: | Luo, X, Tang, Z, Rizo, J, Yu, H. | Deposit date: | 2001-12-12 | Release date: | 2002-01-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol.Cell, 9, 2002
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3Q6S
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4PJW
| crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1), with bound MES | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog | Authors: | Hara, K, Chen, Z, Tomchick, D.R, Yu, H. | Deposit date: | 2014-05-12 | Release date: | 2014-08-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat.Struct.Mol.Biol., 21, 2014
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4PK7
| crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) with bound MES, native proteins | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog | Authors: | Hara, K, Chen, Z, Tomchick, D.R, Yu, H. | Deposit date: | 2014-05-13 | Release date: | 2014-09-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat.Struct.Mol.Biol., 21, 2014
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4PJU
| crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) | Descriptor: | Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog | Authors: | Hara, K, Chen, Z, Tomchick, D.R, Yu, H. | Deposit date: | 2014-05-12 | Release date: | 2014-08-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat.Struct.Mol.Biol., 21, 2014
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4N14
| Crystal structure of Cdc20 and apcin complex | Descriptor: | 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl [(1R)-2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl]carbamate, Cell division cycle protein 20 homolog | Authors: | Luo, X, Tian, W, Yu, H. | Deposit date: | 2013-10-03 | Release date: | 2014-08-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. Nature, 514, 2014
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3DWQ
| Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc | Descriptor: | AZIDE ION, N-PROPANOL, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | Deposit date: | 2008-07-22 | Release date: | 2008-11-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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3DWA
| Crystal structure of the B-subunit of the AB5 toxin from E. coli | Descriptor: | PENTAETHYLENE GLYCOL, Subtilase cytotoxin, subunit B | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | Deposit date: | 2008-07-22 | Release date: | 2008-11-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.084 Å) | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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3DWP
| Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc | Descriptor: | N-glycolyl-alpha-neuraminic acid, PENTAETHYLENE GLYCOL, Subtilase cytotoxin, ... | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | Deposit date: | 2008-07-22 | Release date: | 2008-11-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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5T8V
| Chaetomium thermophilum cohesin loader SCC2, C-terminal fragment | Descriptor: | CITRIC ACID, Putative uncharacterized protein | Authors: | Tomchick, D.R, Yu, H, Kikuchi, S, Ouyang, Z, Borek, D, Otwinowski, Z. | Deposit date: | 2016-09-08 | Release date: | 2016-10-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.798 Å) | Cite: | Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy. Proc.Natl.Acad.Sci.USA, 113, 2016
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5TO2
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5FC2
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5FC3
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5HDT
| Human cohesin regulator Pds5B bound to a Wapl peptide | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Sister chromatid cohesion protein PDS5 homolog B, Wings apart-like protein homolog | Authors: | Ouyang, Z, Tomchick, D.R, Yu, H. | Deposit date: | 2016-01-05 | Release date: | 2016-03-09 | Last modified: | 2020-10-14 | Method: | X-RAY DIFFRACTION (2.711 Å) | Cite: | Structure of the human cohesin regulator Pds5 in complex with Wapl motif To Be Published
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2ESK
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2ESQ
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2ESP
| Human ubiquitin-conjugating enzyme (E2) UbcH5b mutant Ile88Ala | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Ubiquitin-conjugating enzyme E2 D2 | Authors: | Ozkan, E, Yu, H, Deisenhofer, J. | Deposit date: | 2005-10-26 | Release date: | 2005-12-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases Proc.Natl.Acad.Sci.Usa, 102, 2005
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2ESO
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5JB1
| Pseudo-atomic structure of Human Papillomavirus Type 59 L1 Virus-like Particle | Descriptor: | Major capsid protein L1 | Authors: | Li, Z.H, Yan, X.D, Yu, H, Zheng, Q.B, Gu, Y, Li, S.W. | Deposit date: | 2016-04-13 | Release date: | 2016-05-18 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction. Structure, 24, 2016
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