8F28
 
 | | Lysozyme Structures from Single-Entity Crystallization Method NanoAC | | 分子名称: | ACETATE ION, CHLORIDE ION, Lysozyme C, ... | | 著者 | Yang, R, Sankaran, B, Ogbonna, E, Wang, G. | | 登録日 | 2022-11-07 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | A Single-Entity Method for Actively Controlled Nucleation and High-Quality Protein Crystal Synthesis.
Anal.Chem., 95, 2023
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5H0I
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8G5V
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8G6V
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8G8Y
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7UMI
 | | Importin a1 bound to Cp183-CTD | | 分子名称: | HBV-NLS, Importin subunit alpha-1 | | 著者 | Yang, R, Cingolani, G. | | 登録日 | 2022-04-07 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core.
Sci Adv, 10, 2024
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7UCK
 | | 80S translation initiation complex with ac4c(-1) mRNA and Harringtonine | | 分子名称: | 18S rRNA, 28s rRNA, 40S ribosomal protein S10, ... | | 著者 | Yang, R, Arango, D, Sturgill, D, Oberdoerffer, S. | | 登録日 | 2022-03-16 | | 公開日 | 2022-06-01 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.
Mol.Cell, 82, 2022
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7UCJ
 | | Mammalian 80S translation initiation complex with mRNA and Harringtonine | | 分子名称: | 18S rRNA, 28s rRNA, 40S ribosomal protein S10, ... | | 著者 | Yang, R, Arango, D, Sturgill, D, Oberdoerffer, S. | | 登録日 | 2022-03-16 | | 公開日 | 2022-06-01 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.
Mol.Cell, 82, 2022
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1MWN
 | | Solution NMR structure of S100B bound to the high-affinity target peptide TRTK-12 | | 分子名称: | CALCIUM ION, F-actin capping protein alpha-1 subunit, S-100 protein, ... | | 著者 | Inman, K.G, Yang, R, Rustandi, R.R, Miller, K.E, Baldisseri, D.M, Weber, D.J. | | 登録日 | 2002-09-30 | | 公開日 | 2002-12-18 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of S100B bound to the high-affinity target peptide TRTK-12
J.Mol.Biol., 324, 2002
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6BZ9
 | | Crystal structure of human caspase-1 in complex with Ac-FLTD-CMK | | 分子名称: | Ac-FLTD-CMK, Caspase-1, DI(HYDROXYETHYL)ETHER | | 著者 | Xiao, T.S, Yang, J, Liu, Z, Wang, C, Yang, R. | | 登録日 | 2017-12-22 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | | 主引用文献 | Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7SP4
 | | In situ cryo-EM structure of bacteriophage Sf6 gp3:gp7:gp5 complex in conformation 2 at 3.71A resolution | | 分子名称: | Gene 3 protein, Gene 5 protein, Gene 7 protein | | 著者 | Li, F, Cingolani, G, Hou, C, Yang, R. | | 登録日 | 2021-11-02 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine.
Sci Adv, 8, 2022
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7SPU
 | | In situ cryo-EM structure of bacteriophage Sf6 gp3:gp7:gp5 complex in conformation 1 at 3.73A resolution | | 分子名称: | Gene 3 protein, Gene 5 protein, Gene 7 protein | | 著者 | Li, F, Cingolani, G, Hou, C, Yang, R. | | 登録日 | 2021-11-03 | | 公開日 | 2022-11-23 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine.
Sci Adv, 8, 2022
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7SZ6
 | | Kinetically trapped Pseudomonas-phage PaP3 portal protein - delta barrel mutant class-3 | | 分子名称: | Portal protein | | 著者 | Hou, C.-F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | | 登録日 | 2021-11-25 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (6.24 Å) | | 主引用文献 | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
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7SZ4
 | | Kinetically trapped Pseudomonas-phage PaP3 portal protein - delta barrel mutant class-2 | | 分子名称: | Portal protein | | 著者 | Hou, C.-F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | | 登録日 | 2021-11-25 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
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7SXK
 | | Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length | | 分子名称: | Portal protein | | 著者 | Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | | 登録日 | 2021-11-23 | | 公開日 | 2022-04-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
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7SYA
 | | Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length | | 分子名称: | Portal protein | | 著者 | Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | | 登録日 | 2021-11-24 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
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7TJK
 | | S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with docked Orc6 N-terminal domain | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | | 登録日 | 2022-01-16 | | 公開日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
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7TJJ
 | | S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with docked Orc6 N-terminal domain | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | | 登録日 | 2022-01-16 | | 公開日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
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7TJH
 | | S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with flexible Orc6 N-terminal domain | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | | 登録日 | 2022-01-16 | | 公開日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
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7TJI
 | | S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with flexible Orc6 N-terminal domain | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | | 登録日 | 2022-01-16 | | 公開日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
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7TJF
 | | S. cerevisiae ORC bound to 84 bp ARS1 DNA | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA, 84 bp ARS1, ... | | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | | 登録日 | 2022-01-16 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
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8WLR
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8WLO
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3PKN
 | | Crystal structure of MLLE domain of poly(A) binding protein in complex with PAM2 motif of La-related protein 4 (LARP4) | | 分子名称: | IODIDE ION, La-related protein 4, Polyadenylate-binding protein 1, ... | | 著者 | Xie, J, Kozlov, G, Gehring, K. | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability.
Mol.Cell.Biol., 31, 2011
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8HHU
 | | Crystal structure of the SARS-CoV-2 main protease in complex with SY110 | | 分子名称: | (1~{R})-3,3-bis(fluoranyl)-~{N}-[(2~{R})-3-methoxy-1-oxidanylidene-1-[[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(1,3-thiazol-2-ylmethylamino)butan-2-yl]amino]propan-2-yl]cyclohexane-1-carboxamide, 3C-like proteinase nsp5 | | 著者 | Zeng, R, Xie, L.W, Huang, C, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J. | | 登録日 | 2022-11-17 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.258 Å) | | 主引用文献 | A new generation M pro inhibitor with potent activity against SARS-CoV-2 Omicron variants.
Signal Transduct Target Ther, 8, 2023
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