2KM4
 
 | | Solution structure of Rtt103 CTD interacting domain | | 分子名称: | Regulator of Ty1 transposition protein 103 | | 著者 | Lunde, B.M, Reichow, S, Kim, M, Leeper, T.C, Becker, R, Buratowski, S, Meinhart, A, Varani, G. | | 登録日 | 2009-07-20 | | 公開日 | 2010-09-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
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7XEV
 | | Structure of mTRPV2_2-APB | | 分子名称: | 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2 | | 著者 | Su, N. | | 登録日 | 2022-03-31 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
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7XEO
 | | MbetaCD treated state of mTRPV2 | | 分子名称: | Transient receptor potential cation channel subfamily V member 2 | | 著者 | Su, N. | | 登録日 | 2022-03-31 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
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7XEU
 | | Structure of mTRPV2_E2 | | 分子名称: | CHOLESTEROL, Transient receptor potential cation channel subfamily V member 2 | | 著者 | Su, N. | | 登録日 | 2022-03-31 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
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7XEW
 | | Structure of mTRPV2_Q525F | | 分子名称: | Transient receptor potential cation channel subfamily V member 2 | | 著者 | Su, N. | | 登録日 | 2022-03-31 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
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7XER
 | | Structure of mTRPV2_Q525T | | 分子名称: | CHOLESTEROL, Transient receptor potential cation channel subfamily V member 2 | | 著者 | Su, N. | | 登録日 | 2022-03-31 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (2.47 Å) | | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
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7XEM
 | | Cholesterol bound state of mTRPV2 | | 分子名称: | CHOLESTEROL, Transient receptor potential cation channel subfamily V member 2 | | 著者 | Su, N. | | 登録日 | 2022-03-31 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
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7YEP
 | | 2-APB bound state of mTRPV2 | | 分子名称: | 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2 | | 著者 | Su, N. | | 登録日 | 2022-07-06 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
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7WKS
 | | Apo state of AtPIN3 | | 分子名称: | Auxin efflux carrier component 3 | | 著者 | Su, N. | | 登録日 | 2022-01-11 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
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7WKW
 | | NPA bound state of AtPIN3 | | 分子名称: | 2-(naphthalen-1-ylcarbamoyl)benzoic acid, Auxin efflux carrier component 3 | | 著者 | Su, N. | | 登録日 | 2022-01-11 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | | 主引用文献 | Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
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7EQ1
 | | GPR114-Gs-scFv16 complex | | 分子名称: | Adhesion G-protein coupled receptor G5, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Ping, Y. | | 登録日 | 2021-04-28 | | 公開日 | 2022-05-11 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for the tethered peptide activation of adhesion GPCRs.
Nature, 604, 2022
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7WN8
 | | Crystal structure of antibody (BC31M5) binds to CD47 | | 分子名称: | BC31M5 Fab Heavy chain, BC31M5 Fab Light chain, Leukocyte surface antigen CD47, ... | | 著者 | Li, Y, Wang, W, Sui, J, Zhang, S. | | 登録日 | 2022-01-17 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A pH-dependent anti-CD47 antibody that selectively targets solid tumors and improves therapeutic efficacy and safety.
J Hematol Oncol, 16, 2023
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7Y9N
 | | an engineered 5-helix bundle derived from SARS-CoV-2 S2 in complex with HR2P | | 分子名称: | SARS-coV-2 S2 subunit, Spike protein S2',5HB-H2 | | 著者 | Lu, G.W, Lin, X, Guo, L.Y, Lin, S. | | 登録日 | 2022-06-25 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.885 Å) | | 主引用文献 | An engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entry.
Emerg Microbes Infect, 11, 2022
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7XXB
 | | IAA bound state of AtPIN3 | | 分子名称: | 1H-INDOL-3-YLACETIC ACID, Auxin efflux carrier component 3 | | 著者 | Su, N. | | 登録日 | 2022-05-29 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
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5WYH
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5WY2
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5XA6
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6AFR
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with 5-((4-fluoro-1H-imidazol-1-yl)methyl)quinolin-8-ol | | 分子名称: | 5-[(4-fluoranylimidazol-1-yl)methyl]quinolin-8-ol, Bromodomain-containing protein 4 | | 著者 | Xing, J, Zhang, R.K, Zheng, M.Y, Luo, C, Jiang, X.R. | | 登録日 | 2018-08-08 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | | 主引用文献 | Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors
Eur J Med Chem, 163, 2018
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8H89
 | | Capsid of Ralstonia phage GP4 | | 分子名称: | Major capsid protein, Virion associated protein | | 著者 | Liu, H.R, Chen, W.Y. | | 登録日 | 2022-10-22 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A Capsid Structure of Ralstonia solanacearum podoviridae GP4 with a Triangulation Number T = 9.
Viruses, 14, 2022
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8GVJ
 | | Crystal structure of cMET kinase domain bound by D6808 | | 分子名称: | (1^4Z,5^2E)-6^3-(trifluoromethyl)-5^1,5^6-dihydro-1^1H-8-aza-2(3,6)-quinolina-5(1,3)-pyridazina-1(4,1)-pyrazola-6(1,4)-benzenacyclododecaphane-5^6,7-dione, Hepatocyte growth factor receptor | | 著者 | Chen, Y.H, Qu, L.Z. | | 登録日 | 2022-09-15 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment.
J.Med.Chem., 65, 2022
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8H3Z
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7E44
 | | Crystal structure of NudC complexed with dpCoA | | 分子名称: | DEPHOSPHO COENZYME A, NADH pyrophosphatase, ZINC ION | | 著者 | Zhou, W, Guan, Z.Y, Yin, P, Zhang, D.L. | | 登録日 | 2021-02-10 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into dpCoA-RNA decapping by NudC.
Rna Biol., 18, 2021
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8I1V
 | | The asymmetric unit of P22 procapsid | | 分子名称: | Major capsid protein, Scaffolding protein | | 著者 | Xiao, H, Liu, H.R, Cheng, L.P. | | 登録日 | 2023-01-13 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures.
Viruses, 15, 2023
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8I1T
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7FDV
 | | Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 1, CHOLESTEROL, ... | | 著者 | Xu, D, Li, Y.Y, Yang, F.R, Sun, C.R, Pan, J.H, Wang, L, Chen, Z.P, Fang, S.C, Yao, X.B, Hou, W.T, Zhou, C.Z, Chen, Y. | | 登録日 | 2021-07-18 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-06-29 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structure and transport mechanism of the human cholesterol transporter ABCG1.
Cell Rep, 38, 2022
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