7Y9N
an engineered 5-helix bundle derived from SARS-CoV-2 S2 in complex with HR2P
Summary for 7Y9N
Entry DOI | 10.2210/pdb7y9n/pdb |
Descriptor | Spike protein S2',5HB-H2, SARS-coV-2 S2 subunit (3 entities in total) |
Functional Keywords | 5hb, virus protein/inhibitor, virus protein-inhibitor complex |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 2 |
Total formula weight | 30361.70 |
Authors | |
Primary citation | Lin, X.,Guo, L.,Lin, S.,Chen, Z.,Yang, F.,Yang, J.,Wang, L.,Wen, A.,Duan, Y.,Zhang, X.,Dai, Y.,Yin, K.,Yuan, X.,Yu, C.,He, B.,Cao, Y.,Dong, H.,Li, J.,Zhao, Q.,Lu, G. An engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entry. Emerg Microbes Infect, 11:1920-1935, 2022 Cited by PubMed: 35757908DOI: 10.1080/22221751.2022.2095308 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.885 Å) |
Structure validation
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