7XEM

Cholesterol bound state of mTRPV2

Summary for 7XEM

• Entry DOI: 10.2210/pdb7xem/pdb
• EMDB information: 33156
• Descriptor: Transient receptor potential cation channel subfamily V member 2, CHOLESTEROL (3 entities in total)
• Functional Keywords: mtrpv2, chloesterol, structural protein
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 4
• Total formula weight: 345779.40

Authors

Su, N. (deposition date: 2022-03-31, release date: 2022-08-17, Last modification date: 2023-03-01)

• Primary citation: Su, N.,Zhen, W.,Zhang, H.,Xu, L.,Jin, Y.,Chen, X.,Zhao, C.,Wang, Q.,Wang, X.,Li, S.,Wen, H.,Yang, W.,Guo, J.,Yang, F.; Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.; Nat.Chem.Biol., 19:72-80, 2023; PubMed: 36163384; DOI: 10.1038/s41589-022-01139-8

Experimental method

ELECTRON MICROSCOPY (3.17 Å)