7WN8
Crystal structure of antibody (BC31M5) binds to CD47
Summary for 7WN8
Entry DOI | 10.2210/pdb7wn8/pdb |
Descriptor | Leukocyte surface antigen CD47, BC31M5 Fab Heavy chain, BC31M5 Fab Light chain, ... (5 entities in total) |
Functional Keywords | fab, human cd47, complex, antitumor protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 167621.56 |
Authors | |
Primary citation | Li, Y.,Liu, J.,Chen, W.,Wang, W.,Yang, F.,Liu, X.,Sheng, Y.,Du, K.,He, M.,Lyu, X.,Li, H.,Zhao, L.,Wei, Z.,Wang, F.,Zheng, S.,Sui, J. A pH-dependent anti-CD47 antibody that selectively targets solid tumors and improves therapeutic efficacy and safety. J Hematol Oncol, 16:2-2, 2023 Cited by PubMed: 36650558DOI: 10.1186/s13045-023-01399-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)