7WN8
Crystal structure of antibody (BC31M5) binds to CD47
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Leukocyte surface antigen CD47 | polymer | 323 | 35195.4 | 2 | UniProt (Q08722) Pfam (PF08204) Pfam (PF04549) | Homo sapiens (human) | Antigenic surface determinant protein OA3,Integrin-associated protein,IAP,Protein MER6 |
| 2 | C, E (H, P) | BC31M5 Fab Heavy chain | polymer | 230 | 24686.5 | 2 | Homo sapiens (human) | ||
| 3 | D, F (L, Q) | BC31M5 Fab Light chain | polymer | 215 | 23667.2 | 2 | Homo sapiens (human) | ||
| 4 | G, H, I, J, K... (A, C, L, P) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 5 | O, P, Q, R, S... (A, C, H, L, P...) | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 323 (UniProt: Q08722)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | Cys 15 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 167098.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 523.3 | |
| All* | Total formula weight | 167621.6 |
