7WN8
Crystal structure of antibody (BC31M5) binds to CD47
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0022409 | biological_process | positive regulation of cell-cell adhesion |
| A | 0050729 | biological_process | positive regulation of inflammatory response |
| A | 0050766 | biological_process | positive regulation of phagocytosis |
| A | 0070053 | molecular_function | thrombospondin receptor activity |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0022409 | biological_process | positive regulation of cell-cell adhesion |
| C | 0050729 | biological_process | positive regulation of inflammatory response |
| C | 0050766 | biological_process | positive regulation of phagocytosis |
| C | 0070053 | molecular_function | thrombospondin receptor activity |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR193-HIS199 | |
| H | TYR197-HIS203 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 284 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN19-GLU141 | |
| A | VAL198-ALA207 | |
| A | SER257-GLY268 | |
| C | GLN19-GLU141 | |
| C | VAL198-ALA207 | |
| C | SER257-GLY268 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 200 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN142-ILE162 | |
| C | PRO269-MET289 | |
| A | ILE177-PHE197 | |
| A | THR208-PHE228 | |
| A | SER236-LEU256 | |
| A | PRO269-MET289 | |
| C | ASN142-ILE162 | |
| C | ILE177-PHE197 | |
| C | THR208-PHE228 | |
| C | SER236-LEU256 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 104 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | LYS163-THR176 | |
| A | SER229-THR235 | |
| A | LYS290-GLU323 | |
| C | LYS163-THR176 | |
| C | SER229-THR235 | |
| C | LYS290-GLU323 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:18657508 |
| Chain | Residue | Details |
| A | GLN19 | |
| C | GLN19 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P97829 |
| Chain | Residue | Details |
| A | SER89 | |
| C | SER89 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508 |
| Chain | Residue | Details |
| A | ASN23 | |
| C | ASN23 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine |
| Chain | Residue | Details |
| A | ASN34 | |
| C | ASN34 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508, ECO:0000269|PubMed:19349973 |
| Chain | Residue | Details |
| A | ASN50 | |
| C | ASN50 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973 |
| Chain | Residue | Details |
| A | ASN73 | |
| C | ASN73 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | ASN111 | |
| C | ASN111 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN206 | |
| C | ASN206 |
