8GW1
| A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | 分子名称: | Helicase, MANGANESE (II) ION, Non-structural protein 7, ... | 著者 | Yan, L, Rao, Z, Lou, Z. | 登録日 | 2022-09-16 | 公開日 | 2023-10-25 | 最終更新日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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5CB2
| the structure of candida albicans Sey1p in complex with GMPPNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein SEY1 | 著者 | Yan, L, Sun, S, Wang, W, Shi, J, Hu, X, Wang, S, Rao, Z, Hu, J, Lou, Z. | 登録日 | 2015-06-30 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion J.Cell Biol., 210, 2015
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5CA9
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5CA8
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5GNT
| BDLP-like folding of Mitofusin 1 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1 | 著者 | Yan, L, Yu, C, Ming, Z, Rao, Z, Lou, Z, Hu, J. | 登録日 | 2016-07-24 | 公開日 | 2016-11-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.665 Å) | 主引用文献 | the structure of mini-MFN1 in complex with GDP To Be Published
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5GJK
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5YEW
| Structural basis for GTP hydrolysis and conformational change of mitofusin 1 in mediating mitochondrial fusion | 分子名称: | BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Yan, L, Qi, Y, Huang, X, Yu, C. | 登録日 | 2017-09-20 | 公開日 | 2018-01-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion Nat. Struct. Mol. Biol., 25, 2018
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7CYQ
| Cryo-EM structure of an extended SARS-CoV-2 replication and transcription complex reveals an intermediate state in cap synthesis | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Helicase, MAGNESIUM ION, ... | 著者 | Yan, L, Ge, J, Zheng, L, Zhang, Y, Gao, Y, Wang, T, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | 登録日 | 2020-09-04 | 公開日 | 2020-12-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis. Cell, 184, 2021
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7CXN
| Architecture of a SARS-CoV-2 mini replication and transcription complex | 分子名称: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Yan, L, Zhang, Y, Ge, J, Zheng, L, Gao, Y, Wang, T, Jia, Z, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | 登録日 | 2020-09-02 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | 主引用文献 | Architecture of a SARS-CoV-2 mini replication and transcription complex. Nat Commun, 11, 2020
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7CXM
| Architecture of a SARS-CoV-2 mini replication and transcription complex | 分子名称: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Yan, L, Zhang, Y, Ge, J, Zheng, L, Gao, Y, Wang, T, Jia, Z, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | 登録日 | 2020-09-02 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Architecture of a SARS-CoV-2 mini replication and transcription complex. Nat Commun, 11, 2020
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6JSJ
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7EIZ
| Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading | 分子名称: | Helicase, MAGNESIUM ION, Non-structural protein 10, ... | 著者 | Yan, L, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y. | 登録日 | 2021-04-01 | 公開日 | 2021-09-22 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading Cell, 184, 2021
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5YEJ
| Crystal structure of BioQ with its naturel double-stranded DNA operator | 分子名称: | DNA (5'-D(*AP*CP*CP*TP*GP*AP*AP*CP*AP*CP*CP*GP*TP*TP*CP*AP*AP*GP*T)-3'), DNA (5'-D(*AP*CP*TP*TP*GP*AP*AP*CP*GP*GP*TP*GP*TP*TP*CP*AP*GP*GP*T)-3'), TetR family transcriptional regulator | 著者 | Yan, L, Guan, Z.Y, Zou, T.T. | 登録日 | 2017-09-17 | 公開日 | 2018-09-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | 主引用文献 | Structural insights into operator recognition by BioQ in the Mycobacterium smegmatis biotin synthesis pathway. Biochim Biophys Acta Gen Subj, 1862, 2018
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5YEK
| Crystal structure of BioQ | 分子名称: | TetR family transcriptional regulator | 著者 | Yan, L, Guan, Z.Y, Zou, T.T. | 登録日 | 2017-09-17 | 公開日 | 2018-09-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.191 Å) | 主引用文献 | Structural insights into operator recognition by BioQ in the Mycobacterium smegmatis biotin synthesis pathway. Biochim Biophys Acta Gen Subj, 1862, 2018
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7EQ3
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7WZB
| lipopolysaccharide assembly protein LapB (open) | 分子名称: | Lipopolysaccharide assembly protein B, TRIETHYLENE GLYCOL, ZINC ION | 著者 | Yan, L, Dong, H, Li, H, Liu, X, Deng, Z, Dong, C, Zhang, Z. | 登録日 | 2022-02-17 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | lipopolysaccharide assembly protein LapB (open) To Be Published
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7YD3
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7YI6
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5JXR
| Crystal structure of MtISWI | 分子名称: | CHLORIDE ION, Chromatin-remodeling complex ATPase-like protein | 著者 | Chen, Z, Yan, L. | 登録日 | 2016-05-13 | 公開日 | 2016-12-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.404 Å) | 主引用文献 | Structure and regulation of the chromatin remodeller ISWI Nature, 540, 2016
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8X7X
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5JXT
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5YVD
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5ZUV
| Crystal Structure of the Human Coronavirus 229E HR1 motif in complex with pan-CoVs inhibitor EK1 | 分子名称: | CHLORIDE ION, Spike glycoprotein,Spike glycoprotein,inhibitor EK1 | 著者 | Yan, L, Yang, B, Wilson, I.A. | 登録日 | 2018-05-08 | 公開日 | 2019-04-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Sci Adv, 5, 2019
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5ZVM
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5ZVK
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