2FVU
 
 | | Structure of the yeast Sir3 BAH domain | | Descriptor: | Regulatory protein SIR3 | | Authors: | Xu, R.M. | | Deposit date: | 2006-01-31 | | Release date: | 2006-09-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and function of the Saccharomyces cerevisiae Sir3 BAH domain.
Mol.Cell.Biol., 26, 2006
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2H0D
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7CQ2
 | | Crystal structure of Slx1-Slx4 | | Descriptor: | GLYCEROL, SLX4 isoform 1, Structure-specific endonuclease subunit SLX1, ... | | Authors: | Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. | | Deposit date: | 2020-08-08 | | Release date: | 2021-06-16 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
Nucleic Acids Res., 49, 2021
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7CQ3
 | | Crystal structure of Slx1-Slx4 | | Descriptor: | SLX4 isoform 1, SULFATE ION, Structure-specific endonuclease subunit SLX1, ... | | Authors: | Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. | | Deposit date: | 2020-08-08 | | Release date: | 2021-06-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.449 Å) | | Cite: | Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
Nucleic Acids Res., 49, 2021
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7CQ4
 | | Crystal structure of Slx1-Slx4 in complex with 5'flap DNA | | Descriptor: | DNA (27-MER), DNA (5'-D(*AP*GP*GP*AP*CP*AP*TP*CP*TP*TP*TP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*TP*AP*CP*AP*AP*CP*AP*GP*AP*T)-3'), ... | | Authors: | Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. | | Deposit date: | 2020-08-08 | | Release date: | 2021-06-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.294 Å) | | Cite: | Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
Nucleic Acids Res., 49, 2021
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7CCQ
 | | Structure of the 1:1 cGAS-nucleosome complex | | Descriptor: | Cyclic GMP-AMP synthase, DNA (147-MER), Histone H2A type 1-B/E, ... | | Authors: | Cao, D, Han, X, Fan, X, Xu, R.M, Zhang, X. | | Deposit date: | 2020-06-17 | | Release date: | 2020-10-07 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis for nucleosome-mediated inhibition of cGAS activity.
Cell Res., 30, 2020
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5EX7
 | | Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA | | Descriptor: | Brain tumor protein, RNA (5'-R(P*UP*UP*UP*GP*UP*UP*GP*U)-3') | | Authors: | Wang, Y, Yu, Z, Wang, M, Liu, C.P, Yang, N, Xu, R.M. | | Deposit date: | 2015-11-23 | | Release date: | 2015-12-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA
To Be Published
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5EX0
 | | Crystal structure of human SMYD3 in complex with a MAP3K2 peptide | | Descriptor: | ACETIC ACID, Histone-lysine N-methyltransferase SMYD3, MAP3K2 peptide, ... | | Authors: | Fu, W, Liu, N, Qiao, Q, Wang, M, Min, J, Zhu, B, Xu, R.M, Yang, N. | | Deposit date: | 2015-11-23 | | Release date: | 2016-03-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase
J.Biol.Chem., 291, 2016
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5EX3
 | | Crystal structure of human SMYD3 in complex with a VEGFR1 peptide | | Descriptor: | ACETIC ACID, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Qiao, Q, Fu, W, Liu, N, Wang, M, Min, J, Zhu, B, Xu, R.M, Yang, N. | | Deposit date: | 2015-11-23 | | Release date: | 2016-03-09 | | Last modified: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (2.408 Å) | | Cite: | Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase
J.Biol.Chem., 291, 2016
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7CCR
 | | Structure of the 2:2 cGAS-nucleosome complex | | Descriptor: | Cyclic GMP-AMP synthase, DNA (147-MER), Histone H2A type 1-B/E, ... | | Authors: | Cao, D, Han, X, Fan, X, Xu, R.M, Zhang, X. | | Deposit date: | 2020-06-17 | | Release date: | 2020-10-07 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Structural basis for nucleosome-mediated inhibition of cGAS activity.
Cell Res., 30, 2020
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5H1L
 | | Crystal structure of WD40 repeat domains of Gemin5 in complex with 7-nt U4 snRNA fragment | | Descriptor: | GLYCEROL, Gem-associated protein 5, U4 snRNA (5'-R(*AP*UP*UP*UP*UP*UP*G)-3') | | Authors: | Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M. | | Deposit date: | 2016-10-10 | | Release date: | 2016-11-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
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5H1K
 | | Crystal structure of WD40 repeat domains of Gemin5 in complex with 13-nt U4 snRNA fragment | | Descriptor: | Gem-associated protein 5, U4 snRNA (5'-R(*GP*CP*AP*AP*UP*UP*UP*UP*UP*GP*AP*CP*A)-3') | | Authors: | Wang, Y, Jin, W, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M. | | Deposit date: | 2016-10-10 | | Release date: | 2016-11-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
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5H1M
 | | Crystal structure of WD40 repeat domains of Gemin5 in complex with M7G | | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Gem-associated protein 5 | | Authors: | Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M. | | Deposit date: | 2016-10-10 | | Release date: | 2016-11-23 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.492 Å) | | Cite: | Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
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5H1J
 | | Crystal structure of WD40 repeat domains of Gemin5 | | Descriptor: | Gem-associated protein 5 | | Authors: | Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M. | | Deposit date: | 2016-10-10 | | Release date: | 2016-11-23 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
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6JN2
 | | Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10 | | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10 | | Authors: | Song, X, Wang, M, Yang, N, Xu, R.M. | | Deposit date: | 2019-03-13 | | Release date: | 2019-09-18 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7Y61
 | | Cryo-EM structure of the two CAF1LCs bound right-handed Di-tetrasome | | Descriptor: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | | Authors: | Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. | | Deposit date: | 2022-06-18 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (5.6 Å) | | Cite: | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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7Y5O
 | | Crystal structure of human CAF-1 core complex in spacegroup P21 | | Descriptor: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ... | | Authors: | Liu, C.P, Wang, M.Z, Xu, R.M. | | Deposit date: | 2022-06-17 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.57 Å) | | Cite: | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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7Y5K
 | | Crystal structure of human CAF-1 core complex in spacegroup C2221 | | Descriptor: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ... | | Authors: | Liu, C.P, Wang, M.Z, Xu, R.M. | | Deposit date: | 2022-06-17 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.48 Å) | | Cite: | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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7Y5W
 | | Cryo-EM structure of the left-handed Di-tetrasome | | Descriptor: | Histone H3.1, Histone H4, Widom 601 DNA (147-MER) | | Authors: | Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. | | Deposit date: | 2022-06-17 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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7Y5U
 | | Cryo-EM structure of the monomeric human CAF1LC-H3-H4 complex | | Descriptor: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | | Authors: | Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. | | Deposit date: | 2022-06-17 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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7Y5V
 | | Cryo-EM structure of the dimeric human CAF1LC-H3-H4 complex | | Descriptor: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | | Authors: | Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M. | | Deposit date: | 2022-06-17 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (6.1 Å) | | Cite: | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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7Y60
 | | Cryo-EM structure of human CAF1LC bound right-handed Di-tetrasome | | Descriptor: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | | Authors: | Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M. | | Deposit date: | 2022-06-18 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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7Y5L
 | | Crystal structure of human CAF-1 core complex in spacegroup C2 | | Descriptor: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ... | | Authors: | Liu, C.P, Wang, M.Z, Xu, R.M. | | Deposit date: | 2022-06-17 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.42 Å) | | Cite: | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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6INE
 | | Crystal Structure of human ASH1L-MRG15 complex | | Descriptor: | GLYCEROL, Histone-lysine N-methyltransferase ASH1L, Mortality factor 4-like protein 1, ... | | Authors: | Hou, P, Huang, C, Liu, C.P, Yu, T, Yin, Y, Zhu, B, Xu, R.M. | | Deposit date: | 2018-10-25 | | Release date: | 2019-03-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.
Structure, 27, 2019
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6KN5
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