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5GVT
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BU of 5gvt by Molmil
Crystal structures of the serine protease domain of murine plasma kallikrein
分子名称: Plasma kallikrein, alpha-D-mannopyranose, beta-D-mannopyranose
著者Xu, M, Jiang, L, Huang, M.
登録日2016-09-06
公開日2017-11-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal Structures of the Serine Protease Domain of Murine Plasma Kallikrein
Chin.J.Struct.Chem., 36, 2017
7V4Y
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BU of 7v4y by Molmil
TTHA1264/TTHA1265 complex
分子名称: Putative zinc protease, ZINC ION, Zinc-dependent peptidase
著者Xu, M, Xu, Q, Ran, T, Wang, W, Sun, B, Wang, Q.
登録日2021-08-16
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of TTHA1265 and TTHA1264/TTHA1265 complex reveal an intrinsic heterodimeric assembly.
Int.J.Biol.Macromol., 207, 2022
8TA2
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BU of 8ta2 by Molmil
Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with bound inhibitor AK-42
分子名称: 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, CHLORIDE ION, Chloride channel protein 2
著者Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M.
登録日2023-06-26
公開日2024-01-31
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
8TA3
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BU of 8ta3 by Molmil
Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain Apo state with resolved N-terminal hairpin
分子名称: CHLORIDE ION, Chloride channel protein 2
著者Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M.
登録日2023-06-26
公開日2024-01-31
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
8TA5
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Title: Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with asymmetric C-terminal
分子名称: Chloride channel protein 2
著者Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M.
登録日2023-06-26
公開日2024-01-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
8TA4
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BU of 8ta4 by Molmil
Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with symmetric C-terminal
分子名称: CHLORIDE ION, Chloride channel protein 2
著者Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M.
登録日2023-06-26
公開日2024-01-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
8TA6
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Cryo-EM structure of the human CLC-2 chloride channel C-terminal domain
分子名称: Chloride channel protein 2
著者Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M.
登録日2023-06-26
公開日2024-01-31
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.03 Å)
主引用文献CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
8H0M
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BU of 8h0m by Molmil
Crystal structure of VioD
分子名称: (2S)-2-ethylhexan-1-ol, FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, ...
著者Xu, M, Ran, T, Wang, W.
登録日2022-09-29
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway.
Proteins, 91, 2023
5F8X
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BU of 5f8x by Molmil
The crystal structure of human plasma kallikrein in complex with its peptide inhibitor pkalin-3
分子名称: CYS-PRO-ALA-ARG-PHE-M70-ALA-LEU-TRP-CYS, Plasma kallikrein, SULFATE ION, ...
著者Xu, M, Jiang, L, Xu, P, Luo, Z, Andreasen, P, Huang, M.
登録日2015-12-09
公開日2016-12-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The Crystal Structure Of Human Plasma Kallikrein In Complex With Its Peptide Inhibitor Pkalin-3
To Be Published
5F8Z
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BU of 5f8z by Molmil
The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-1
分子名称: CYS-PRO-ALA-ARG-PHE-M70-ALA-LEU-PHE-CYS, Plasma kallikrein LIGHT CHAIN, SULFATE ION, ...
著者Xu, M, Jiang, L, Xu, P, Luo, Z, Andreasen, P, Huang, M.
登録日2015-12-09
公開日2016-12-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-1
To Be Published
5F8T
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BU of 5f8t by Molmil
The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2
分子名称: CYS-PRO-LYS-ARG-PHE-M70-ALA-LEU-PHE-CYS, Plasma kallikrein light chain, SULFATE ION, ...
著者Xu, M, Jiang, L, Xu, P, Luo, Z, Andreasen, P, Huang, M.
登録日2015-12-09
公開日2016-12-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2
To Be Published
6A8O
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BU of 6a8o by Molmil
Crystal structures of the serine protease domain of murine plasma kallikrein with peptide inhibitor mupain-1-16
分子名称: Plasma kallikrein, alpha-D-mannopyranose, peptide inhibitor,, ...
著者Xu, M, Jiang, L, Huang, M.
登録日2018-07-09
公開日2019-07-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Crystal structure of plasma kallikrein reveals the unusual flexibility of the S1 pocket triggered by Glu217.
Febs Lett., 592, 2018
5GZS
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BU of 5gzs by Molmil
Structure of VC protein
分子名称: ARGININE, GGDEF family protein
著者Xu, M, Wang, Y.Z, Yang, X.A, Xie, W, Jiang, T.
登録日2016-10-01
公開日2017-08-16
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural studies of the periplasmic portion of the diguanylate cyclase CdgH from Vibrio cholerae.
Sci Rep, 7, 2017
3GGR
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BU of 3ggr by Molmil
Crystal Structure of the Human Rad9-Hus1-Rad1 complex
分子名称: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1
著者Xu, M, Bai, L, Hang, H.Y, Jiang, T.
登録日2009-03-02
公開日2009-06-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex
J.Biol.Chem., 284, 2009
5EAZ
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BU of 5eaz by Molmil
crystal form I of YfiB belonging to space groups P21
分子名称: SULFATE ION, YfiB
著者Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T.
登録日2015-10-17
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
5EB3
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BU of 5eb3 by Molmil
VB6-bound protein
分子名称: 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol, SULFATE ION, YfiR
著者Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T.
登録日2015-10-17
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
5EB0
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BU of 5eb0 by Molmil
crystal form II of YfiB belonging to P41
分子名称: SULFATE ION, YfiB
著者Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T.
登録日2015-10-17
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
5EB2
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BU of 5eb2 by Molmil
Trp-bound YfiR
分子名称: SULFATE ION, TRYPTOPHAN, YfiR
著者Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T.
登録日2015-10-17
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.709 Å)
主引用文献Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
5EB1
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BU of 5eb1 by Molmil
the YfiB-YfiR complex
分子名称: SULFATE ION, YfiB, YfiR
著者Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T.
登録日2015-10-17
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
8YL9
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BU of 8yl9 by Molmil
Crystal structures of terpene synthases complexed with a substrate mimic
分子名称: MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE, ...
著者Xu, M, Ma, M.
登録日2024-03-05
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Insights into the Terpene Cyclization Domains of Two Fungal Sesterterpene Synthases and Enzymatic Engineering for Sesterterpene Diversification.
Angew.Chem.Int.Ed.Engl., 2024
8YLA
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BU of 8yla by Molmil
Crystal structures of terpene synthases complexed with a substrate mimic
分子名称: MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE, ...
著者Xu, M, Ma, M.
登録日2024-03-05
公開日2024-04-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural Insights into the Terpene Cyclization Domains of Two Fungal Sesterterpene Synthases and Enzymatic Engineering for Sesterterpene Diversification.
Angew.Chem.Int.Ed.Engl., 2024
8GQR
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BU of 8gqr by Molmil
Crystal structure of VioD with FAD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ...
著者Ran, T, Wang, W, Xu, M.
登録日2022-08-30
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway.
Proteins, 91, 2023
7EV3
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Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-10 and ATP
分子名称: (5S)-5-[(1R)-1-(4-fluoranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-05-20
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7EV2
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Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-11 and ATP
分子名称: (5S)-5-[(1R)-1-(4-chloranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-05-20
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7DB7
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BU of 7db7 by Molmil
Crystal structure of Mycobacterium tuberculosis phenylalanyl-tRNA synthetase in complex with compound GDI05-001
分子名称: 1-[3-[2-(1H-indol-3-yl)ethylsulfamoyl]phenyl]-3-(1,3-thiazol-2-yl)urea, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, ...
著者Xu, M, Zhang, X, Xu, L, Chen, S.
登録日2020-10-19
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis .
J.Biol.Chem., 2021

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