7DBA
 
 | | RYX in complex with tubulin | | 分子名称: | 2-(1-methylindol-4-yl)-7-(3,4,5-trimethoxyphenyl)-1~{H}-benzimidazole, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wu, C.Y, Wang, Y.X. | | 登録日 | 2020-10-19 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.461 Å) | | 主引用文献 | RYX in complex with tubulin
To Be Published
|
|
7DBB
 | | SSE in complex with tubulin | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-phenyl-3-(3,4,5-trimethoxyphenyl)-3,4-dihydropyrazole-2-carbothioamide, CALCIUM ION, ... | | 著者 | Wu, C.Y, Wang, Y.X. | | 登録日 | 2020-10-19 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | SSE in complex with tubulin
To Be Published
|
|
7DBC
 | | PRA in complex with tubulin | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Wu, C.Y, Wang, Y.X. | | 登録日 | 2020-10-19 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | PRA in complex with tubulin
To Be Published
|
|
7DBD
 | | 444 in complex with tubulin | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Wu, C.Y, Wang, Y.X. | | 登録日 | 2020-10-19 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.094 Å) | | 主引用文献 | 444 in complex with tubulin
To Be Published
|
|
7DB9
 | | IC1 in complex with tubulin | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE, CALCIUM ION, ... | | 著者 | Wu, C.Y, Wang, Y.X. | | 登録日 | 2020-10-19 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.845 Å) | | 主引用文献 | IC1 in complex with tubulin
To Be Published
|
|
7XBI
 | | The crystal structure of human TrkA kinase bound to the inhibitor | | 分子名称: | 4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]-~{N}-[3-(1-methylpyrazol-4-yl)-1~{H}-indazol-5-yl]-2-(trifluoromethyl)benzamide, CHLORIDE ION, High affinity nerve growth factor receptor | | 著者 | Wu, C.Y, Wang, G, Ouyang, L. | | 登録日 | 2022-03-21 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | The crystal structure of human TrkA kinase bound to the inhibitor
To be published
|
|
6K80
 | | Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Complex with CoA and Tryptophol | | 分子名称: | 2-(1H-indol-3-yl)ethanol, ACETYL COENZYME *A, Dopamine N-acetyltransferase | | 著者 | Wu, C.Y, Hu, I.C, Yang, Y.C, Cheng, H.C, Lyu, P.C. | | 登録日 | 2019-06-11 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | An essential role of acetyl coenzyme A in the catalytic cycle of insect arylalkylamine N-acetyltransferase.
Commun Biol, 3, 2020
|
|
1FSW
 | | AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR CEPHALOTHINBORONIC ACID | | 分子名称: | CEPHALOSPORINASE, N-2-THIOPHEN-2-YL-ACETAMIDE BORONIC ACID, PHOSPHATE ION | | 著者 | Caselli, E, Powers, R.A, Blaszczak, L.C, Wu, C.Y, Prati, F, Shoichet, B.K. | | 登録日 | 2000-09-11 | | 公開日 | 2001-03-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases.
Chem.Biol., 8, 2001
|
|
1FSY
 | | AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR CLOXACILLINBORONIC ACID | | 分子名称: | CEPHALOSPORINASE, N-[5-METHYL-3-O-TOLYL-ISOXAZOLE-4-CARBOXYLIC ACID AMIDE] BORONIC ACID, PHOSPHATE ION | | 著者 | Caselli, E, Powers, R.A, Blasczcak, L.C, Wu, C.Y, Prati, F, Shoichet, B.K. | | 登録日 | 2000-09-11 | | 公開日 | 2001-03-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases.
Chem.Biol., 8, 2001
|
|
5J6A
 | | Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS46 | | 分子名称: | (3S)-3-amino-4-[4-({2-[(2,4-dihydroxyphenyl)sulfonyl]-2H-isoindol-5-yl}amino)piperidin-1-yl]-4-oxobutanamide, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | | 著者 | Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Wynn, R.M, Chuang, D.T. | | 登録日 | 2016-04-04 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.045 Å) | | 主引用文献 | Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors.
J. Med. Chem., 60, 2017
|
|
8HY7
 | | EGFR kinase domain mutant "TMLR" with compound 28f | | 分子名称: | Epidermal growth factor receptor, ~{N}-[3-[[6-fluoranyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]quinazolin-4-yl]amino]phenyl]prop-2-enamide | | 著者 | Wang, Y.X, Wu, C.Y. | | 登録日 | 2023-01-06 | | 公開日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | The crystal structure of EGFR kinase domain(T790M/L858R) in complex with compound 28f
To Be Published
|
|
8I0B
 | | The crystal structure of human glutamate receptor 2 in complex with LT-102 | | 分子名称: | 8-[4-(2-fluorophenyl)phenyl]-3,4-dihydro-1,2$l^{6},3-benzoxathiazine 2,2-dioxide, CHLORIDE ION, Glutamate receptor 2,Isoform Flip of Glutamate receptor 2, ... | | 著者 | Qi, X.Y, Wu, C.Y. | | 登録日 | 2023-01-10 | | 公開日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structure of the human GluA2 LBD in complex with LT-102
To Be Published
|
|
8GUF
 | |
8HCG
 | | Crystal structure of mTREX1-dAMP complex | | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
|
|
8HCH
 | | Crystal structure of mTREX1-Uridine complex | | 分子名称: | MAGNESIUM ION, Three-prime repair exonuclease 1, URIDINE | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
|
|
8HCD
 | | Crystal structure of mTREX1-DNA product complex (dNMP) | | 分子名称: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, COBALT (II) ION, ... | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
|
|
8HCF
 | | Crystal structure of mTREX1-UMP complex | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Three-prime repair exonuclease 1, ... | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
|
|
8HCC
 | | Crystal structure of mTREX1-RNA product complex (AMP) | | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, SODIUM ION, ... | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
|
|
8HCE
 | | Crystal structure of mTREX1-CMP complex | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMMONIUM ION, CYTIDINE-5'-MONOPHOSPHATE, ... | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
|
|
5GIH
 | |
5GIF
 | | Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Binary Complex with Acetyl-CoA | | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, ACETYL COENZYME *A, Dopamine N-acetyltransferase | | 著者 | Yang, Y.C, Wu, C.Y, Cheng, H.C, Lyu, P.C. | | 登録日 | 2016-06-23 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Binary Complex with Acetyl-CoA
To Be Published
|
|
5GIG
 | | Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-dopamine | | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, COENZYME A, Dopamine N-acetyltransferase, ... | | 著者 | Yang, Y.C, Wu, C.Y, Cheng, H.C, Lyu, P.C. | | 登録日 | 2016-06-23 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-dopamine
To Be Published
|
|
5GII
 | |
5J71
 | | Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS35 | | 分子名称: | 4-({5-[(piperidin-4-yl)amino]-1,3-dihydro-2H-isoindol-2-yl}sulfonyl)benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, ... | | 著者 | Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Wynn, R.M, Chuang, D.T. | | 登録日 | 2016-04-05 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors.
J. Med. Chem., 60, 2017
|
|
7CEM
 | | Crystal Structure of YbeA CP74 W7F | | 分子名称: | Ribosomal RNA large subunit methyltransferase H,Ribosomal RNA large subunit methyltransferase H | | 著者 | Liu, C.Y, Wu, C.Y, Lai, C.H, Hsu, S.T.D, Lyu, P.C. | | 登録日 | 2020-06-23 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4251 Å) | | 主引用文献 | Crystal Structure of YbeA CP74 W7F
To Be Published
|
|
