7XBI

The crystal structure of human TrkA kinase bound to the inhibitor

Summary for 7XBI

• Entry DOI: 10.2210/pdb7xbi/pdb
• Descriptor: High affinity nerve growth factor receptor, 4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]-~{N}-[3-(1-methylpyrazol-4-yl)-1~{H}-indazol-5-yl]-2-(trifluoromethyl)benzamide, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: kinase, inhibitor, trka, ntrk, cytosolic protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 35989.67

Authors

Wu, C.Y.,Wang, G.,Ouyang, L. (deposition date: 2022-03-21, release date: 2023-03-29, Last modification date: 2023-11-29)

• Primary citation: Wu, C.Y.,Wang, G.,Ouyang, L.; The crystal structure of human TrkA kinase bound to the inhibitor; To be published,

Experimental method

X-RAY DIFFRACTION (2.16 Å)