8HY7

EGFR kinase domain mutant "TMLR" with compound 28f

Summary for 8HY7

• Entry DOI: 10.2210/pdb8hy7/pdb
• Descriptor: Epidermal growth factor receptor, ~{N}-[3-[[6-fluoranyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]quinazolin-4-yl]amino]phenyl]prop-2-enamide (3 entities in total)
• Functional Keywords: inhibitor, complex, egfr, structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37989.91

Authors

Wang, Y.X.,Wu, C.Y. (deposition date: 2023-01-06, release date: 2023-08-23)

• Primary citation: Wang, Y.X.,Wu, C.Y.; The crystal structure of EGFR kinase domain(T790M/L858R) in complex with compound 28f; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.91 Å)