PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Crystal structure-based design and disovery of a novel PARP1 antiagonist (BL-PA10) that induces apoptosis and inhibits metastasis in triple negative breast cancer
Descriptor:	Amitriptyline, GLYCEROL, Poly [ADP-ribose] polymerase 1, ...
Authors:	Fu, L, Peng, H, Zhang, L, Ouyang, L.
Deposit date:	2015-12-30
Release date:	2016-03-09
Last modified:	2024-03-20
Method:	X-RAY DIFFRACTION (4.01 Å)
Cite:	Crystal structure-based discovery of a novel synthesized PARP1 inhibitor (OL-1) with apoptosis-inducing mechanisms in triple-negative breast cancer. Sci Rep, 6, 2016

The crystal structure of human TrkA kinase bound to the inhibitor
Descriptor:	4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]-~{N}-[3-(1-methylpyrazol-4-yl)-1~{H}-indazol-5-yl]-2-(trifluoromethyl)benzamide, CHLORIDE ION, High affinity nerve growth factor receptor
Authors:	Wu, C.Y, Wang, G, Ouyang, L.
Deposit date:	2022-03-21
Release date:	2023-03-29
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.16 Å)
Cite:	The crystal structure of human TrkA kinase bound to the inhibitor To be published