1FSY

AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR CLOXACILLINBORONIC ACID

Summary for 1FSY

Entry DOI	10.2210/pdb1fsy/pdb
Related	1C3B 1FSW 2BLS 3BLS
Descriptor	CEPHALOSPORINASE, PHOSPHATE ION, N-[5-METHYL-3-O-TOLYL-ISOXAZOLE-4-CARBOXYLIC ACID AMIDE] BORONIC ACID, ... (4 entities in total)
Functional Keywords	cephalosporinase, beta-lactamase, serine hydrolase, hydrolase
Biological source	Escherichia coli
Cellular location	Periplasm: P00811
Total number of polymer chains	2
Total formula weight	79745.71
Authors	Caselli, E.,Powers, R.A.,Blasczcak, L.C.,Wu, C.Y.,Prati, F.,Shoichet, B.K. (deposition date: 2000-09-11, release date: 2001-03-14, Last modification date: 2011-07-13)
Primary citation	Caselli, E.,Powers, R.A.,Blasczcak, L.C.,Wu, C.Y.,Prati, F.,Shoichet, B.K. Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases. Chem.Biol., 8:17-31, 2001 Cited by PubMed: 11182316 DOI: 10.1016/S1074-5521(00)00052-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation