4PSG
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6TXH
| Crystal structure of thermotoga maritima Ferritin in apo form | 分子名称: | EICOSANE, Ferritin, GLYCEROL, ... | 著者 | Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S. | 登録日 | 2020-01-14 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | 主引用文献 | A single residue can modulate nanocage assembly in salt dependent ferritin. Nanoscale, 13, 2021
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6TXL
| Crystal structure of thermotoga maritima E65Q Ferritin | 分子名称: | EICOSANE, FE (III) ION, Ferritin, ... | 著者 | Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S. | 登録日 | 2020-01-14 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | A single residue can modulate nanocage assembly in salt dependent ferritin. Nanoscale, 13, 2021
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6TXN
| Crystal structure of thermotoga maritima Ferritin in apo form | 分子名称: | EICOSANE, Ferritin, GLYCEROL, ... | 著者 | Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S. | 登録日 | 2020-01-14 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | A single residue can modulate nanocage assembly in salt dependent ferritin. Nanoscale, 13, 2021
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6TXM
| Crystal structure of thermotoga maritima E65R Ferritin | 分子名称: | EICOSANE, Ferritin, GLYCEROL, ... | 著者 | Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S. | 登録日 | 2020-01-14 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | 主引用文献 | A single residue can modulate nanocage assembly in salt dependent ferritin. Nanoscale, 13, 2021
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6TXJ
| Crystal structure of thermotoga maritima A42V E65D Ferritin | 分子名称: | EICOSANE, FE (III) ION, Ferritin, ... | 著者 | Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S, Biela, A.P. | 登録日 | 2020-01-14 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | A single residue can modulate nanocage assembly in salt dependent ferritin. Nanoscale, 13, 2021
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6TXK
| Crystal structure of thermotoga maritima E65K Ferritin | 分子名称: | EICOSANE, FE (III) ION, Ferritin, ... | 著者 | Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S. | 登録日 | 2020-01-14 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.359 Å) | 主引用文献 | A single residue can modulate nanocage assembly in salt dependent ferritin. Nanoscale, 13, 2021
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6TXI
| Crystal structure of thermotoga maritima E65A Ferritin | 分子名称: | EICOSANE, FE (III) ION, Ferritin, ... | 著者 | Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S. | 登録日 | 2020-01-14 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.759 Å) | 主引用文献 | A single residue can modulate nanocage assembly in salt dependent ferritin. Nanoscale, 13, 2021
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4IQB
| High Resolution Crystal Structure of C.elegans Thymidylate Synthase | 分子名称: | SULFATE ION, Thymidylate synthase | 著者 | Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. | 登録日 | 2013-01-11 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS. J. Mol. Graph. Model., 77, 2017
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7PQ7
| Crystal structure of Campylobacter jejuni DsbA1 | 分子名称: | TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, Thiol:disulfide interchange protein DsbA | 著者 | Wilk, P, Orlikowska, M, Banas, A.M, Bocian-Ostrzycka, K.M, Jagusztyn-Krynicka, E.K. | 登録日 | 2021-09-16 | 公開日 | 2021-12-29 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Interplay between DsbA1, DsbA2 and C8J_1298 Periplasmic Oxidoreductases of Campylobacter jejuni and Their Impact on Bacterial Physiology and Pathogenesis. Int J Mol Sci, 22, 2021
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7PQF
| Crystal structure of Campylobacter jejuni DsbA2 | 分子名称: | Thiol:disulfide interchange protein DsbA/DsbL | 著者 | Wilk, P, Banas, A.M, Bocian-Ostrzycka, K.M, Jagusztyn-Krynicka, E.K. | 登録日 | 2021-09-17 | 公開日 | 2021-12-29 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Interplay between DsbA1, DsbA2 and C8J_1298 Periplasmic Oxidoreductases of Campylobacter jejuni and Their Impact on Bacterial Physiology and Pathogenesis. Int J Mol Sci, 22, 2021
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5M4Z
| Crystal structure of the complex of T.spiralis thymidylate synthase with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate, crystallized in the presence of N(5,10)-methylenetetrahydrofolate | 分子名称: | GLYCEROL, Thymidylate synthase, [(2~{R},3~{S},5~{R})-5-[(4~{E})-4-hydroxyimino-2-oxidanylidene-1,3-diazinan-1-yl]-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate | 著者 | Wilk, P, Maj, P, Jarmula, A, Dowiercial, A, Rode, W. | 登録日 | 2016-10-19 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.179 Å) | 主引用文献 | Molecular Mechanism of Thymidylate Synthase Inhibition by N 4 -Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies. Int J Mol Sci, 22, 2021
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7B9P
| Structure of Ribonucleotide reductase from Rhodobacter sphaeroides | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Vitamin B12-dependent ribonucleotide reductase | 著者 | Wilk, P, Feiler, C, Loderer, C, Kabinger, F. | 登録日 | 2020-12-14 | 公開日 | 2022-01-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.646 Å) | 主引用文献 | HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase. Biochemistry, 61, 2022
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5BY6
| Crystal structure of Trichinella spiralis thymidylate synthase complexed with dUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, ... | 著者 | Dowiercial, A, Jarmula, A, Rypniewski, W, Fraczyk, T, Wilk, P, Rode, W. | 登録日 | 2015-06-10 | 公開日 | 2015-06-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS. J. Mol. Graph. Model., 77, 2017
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8P61
| Crystal structure of O'nyong'nyong virus capsid protease (106-256) | 分子名称: | Capsid protein, GLYCEROL, SULFATE ION | 著者 | Plewka, J, Chykunova, Y, Wilk, P, Sienczyk, M, Dubin, G, Pyrc, K. | 登録日 | 2023-05-24 | 公開日 | 2024-03-06 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Autoinhibition of suicidal capsid protease from O'nyong'nyong virus. Int.J.Biol.Macromol., 262, 2024
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8A0F
| Crystal structure of human deoxyhypusine synthase variant K329A in complex with NAD and SPD | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, Deoxyhypusine synthase, ... | 著者 | Wator, E, Wilk, P, Grudnik, P. | 登録日 | 2022-05-27 | 公開日 | 2023-04-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders. Nat Commun, 14, 2023
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8A0G
| Human deoxyhypusine synthase with trapped transition state | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,3-DIAMINOPROPANE, Deoxyhypusine synthase, ... | 著者 | Wator, E, Wilk, P, Grudnik, P. | 登録日 | 2022-05-27 | 公開日 | 2023-04-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders. Nat Commun, 14, 2023
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8A0E
| CryoEM structure of DHS-eIF5A1 complex | 分子名称: | Deoxyhypusine synthase, Eukaryotic translation initiation factor 5A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Wator, E, Wilk, P, Biela, A.P, Rawski, M, Grudnik, P. | 登録日 | 2022-05-27 | 公開日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders. Nat Commun, 14, 2023
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5FCT
| Mouse thymidylate synthase in ternary complex with FdUMP and methylenetetrahydrofolate. | 分子名称: | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Thymidylate synthase | 著者 | Dowiercial, A, Wilk, P, Jarmula, A, Rode, W. | 登録日 | 2015-12-15 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme Struct Chem, 2016
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6XXI
| Crystal Structure of Human Deoxyhypusine Synthase in complex with NAD | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ... | 著者 | Wator, E, Wilk, P, Grudnik, P. | 登録日 | 2020-01-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.679 Å) | 主引用文献 | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
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6XXK
| Crystal Structure of Human Deoxyhypusine Synthase in complex with spermidine | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ... | 著者 | Wator, E, Wilk, P, Grudnik, P. | 登録日 | 2020-01-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
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6XXM
| Crystal Structure of Human Deoxyhypusine Synthase in complex with putrescine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,4-DIAMINOBUTANE, Deoxyhypusine synthase | 著者 | Wator, E, Wilk, P, Grudnik, P. | 登録日 | 2020-01-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
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6XXJ
| Crystal Structure of Human Deoxyhypusine Synthase in complex with spermidine and NAD | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ... | 著者 | Wator, E, Wilk, P, Grudnik, P. | 登録日 | 2020-01-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
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6XXH
| Crystal Structure of Human Deoxyhypusine Synthase in apo form | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, BETA-MERCAPTOETHANOL, ... | 著者 | Wator, E, Wilk, P, Grudnik, P. | 登録日 | 2020-01-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
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6XXL
| Crystal Structure of Human Deoxyhypusine Synthase in complex with spermine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ACETATE ION, ... | 著者 | Wator, E, Wilk, P, Grudnik, P. | 登録日 | 2020-01-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
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