6XXM

Crystal Structure of Human Deoxyhypusine Synthase in complex with putrescine

Summary for 6XXM

Entry DOI	10.2210/pdb6xxm/pdb
Descriptor	Deoxyhypusine synthase, 1,4-DIAMINOBUTANE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
Functional Keywords	hypusination, deoxyhypusine synthase, eif5a, translation, hypusine, posttranslational modification, polyamines, deoxyhypusine, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	82415.54
Authors	Wator, E.,Wilk, P.,Grudnik, P. (deposition date: 2020-01-27, release date: 2020-04-15, Last modification date: 2024-01-24)
Primary citation	Wator, E.,Wilk, P.,Grudnik, P. Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10:-, 2020 Cited by PubMed: 32235505 DOI: 10.3390/biom10040522 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.67 Å)

Structure validation