Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4AOJ
DownloadVisualize
BU of 4aoj by Molmil
Human TrkA in complex with the inhibitor AZ-23
分子名称: 5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR, ZINC ION
著者Wang, T, Lamb, M.L, Block, M.H, Davies, A.M, Han, Y, Hoffmann, E, Ioannidis, S, Josey, J.A, Liu, Z, Lyne, P.D, MacIntyre, T, Mohr, P.J, Omer, C.A, Sjogren, T, Thress, K, Wang, B, Wang, H, Yu, D, Zhang, H.
登録日2012-03-28
公開日2012-08-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Discovery of Disubstituted Imidazo[4,5-B]Pyridines and Purines as Potent Trka Inhibitors
Acs Med.Chem.Lett., 3, 2012
4ZS3
DownloadVisualize
BU of 4zs3 by Molmil
Structural complex of 5-aminofluorescein bound to the FTO protein
分子名称: 2-OXOGLUTARIC ACID, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ...
著者Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X.
登録日2015-05-13
公開日2015-11-04
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
4ZS2
DownloadVisualize
BU of 4zs2 by Molmil
Structural complex of FTO/fluorescein
分子名称: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, ...
著者Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X.
登録日2015-05-13
公開日2015-11-04
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
4FZX
DownloadVisualize
BU of 4fzx by Molmil
Exonuclease X in complex with 3' overhanging duplex DNA
分子名称: DNA (5'-D(P*CP*GP*GP*AP*TP*CP*CP*AP*CP*AP*AP*TP*GP*AP*CP*CP*T)-3'), DNA (5'-D(P*GP*TP*CP*AP*TP*TP*GP*TP*GP*GP*AP*TP*CP*CP*GP*AP*G)-3'), Exodeoxyribonuclease 10, ...
著者Wang, T, Sun, H, Cheng, F, Bi, L, Jiang, T.
登録日2012-07-08
公開日2013-07-03
最終更新日2013-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease
Nucleic Acids Res., 41, 2013
4FZY
DownloadVisualize
BU of 4fzy by Molmil
Exonuclease X in complex with 12bp blunt-ended dsDNA
分子名称: DNA (5'-D(*TP*GP*TP*AP*GP*AP*TP*TP*CP*GP*AP*G)-3'), DNA (5'-D(P*CP*TP*CP*GP*AP*AP*TP*CP*TP*AP*CP*A)-3'), Exodeoxyribonuclease 10, ...
著者Wang, T, Sun, H, Cheng, F, Bi, L, Jiang, T.
登録日2012-07-08
公開日2013-07-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease
Nucleic Acids Res., 41, 2013
4FZZ
DownloadVisualize
BU of 4fzz by Molmil
Exonuclease X in complex with 5' overhanging duplex DNA
分子名称: DNA (5'-D(*GP*TP*CP*AP*TP*TP*GP*TP*GP*GP*AP*TP*CP*CP*GP*AP*G)-3'), Exodeoxyribonuclease 10, SODIUM ION
著者Wang, T, Sun, H, Cheng, F, Bi, L, Jiang, T.
登録日2012-07-08
公開日2013-07-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease
Nucleic Acids Res., 41, 2013
4EEQ
DownloadVisualize
BU of 4eeq by Molmil
Crystal structure of E. faecalis DNA ligase with inhibitor
分子名称: 4-amino-2-(cyclopentyloxy)pyrimidine-5-carboxamide, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, ...
著者Wang, T, Charifson, P, Wei, Y.
登録日2012-03-28
公開日2013-04-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Design, Synthesis and Activity Evaluation of Potent NAD+ DNA Ligase Inhibitors as Potential Antibacterial Agents.
To be Published
3M91
DownloadVisualize
BU of 3m91 by Molmil
Crystal structure of the prokaryotic ubiquitin-like protein (Pup) complexed with the amino terminal coiled coil of the Mycobacterium tuberculosis proteasomal ATPase Mpa
分子名称: Prokaryotic ubiquitin-like protein pup, Proteasome-associated ATPase
著者Wang, T, Li, H.
登録日2010-03-19
公開日2010-10-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation.
Nat.Struct.Mol.Biol., 17, 2010
3NAO
DownloadVisualize
BU of 3nao by Molmil
A DNA Crystal Designed to Contain Two Molecules per Asymmetric Unit Cell
分子名称: DNA (5'-D(*AP*GP*CP*CP*TP*AP*CP*CP*TP*GP*CP*GP*TP*GP*GP*AP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*CP*TP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), ...
著者Wang, T, Sha, R, Birktoft, J.J, Zheng, J, Mao, M, Seeman, N.C.
登録日2010-06-02
公開日2011-11-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (5.03 Å)
主引用文献A DNA crystal designed to contain two molecules per asymmetric unit.
J.Am.Chem.Soc., 132, 2010
1ZMF
DownloadVisualize
BU of 1zmf by Molmil
C domain of human cyclophilin-33(hcyp33)
分子名称: Peptidyl-prolyl cis-trans isomerase E
著者Wang, T, Yun, C.-H, Gu, S.-Y, Chang, W.-R, Liang, D.-C.
登録日2005-05-10
公開日2005-08-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献1.88A crystal structure of the C domain of hCyP33: A novel domain of peptidyl-prolyl cis-trans isomerase
Biochem.Biophys.Res.Commun., 333, 2005
4FPD
DownloadVisualize
BU of 4fpd by Molmil
Deprotonation of D96 in bacteriorhodopsin opens the proton uptake pathway
分子名称: 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, Bacteriorhodopsin, CHLORIDE ION, ...
著者Wang, T, Sessions, A.O, Lunde, C.S, Rouani, S, Glaeser, R.M, Facciotti, M.T, Duan, Y.
登録日2012-06-22
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Deprotonation of d96 in bacteriorhodopsin opens the proton uptake pathway.
Structure, 21, 2013
6KPP
DownloadVisualize
BU of 6kpp by Molmil
BNC105 in complex with tubulin
分子名称: (6-methoxy-2-methyl-7-oxidanyl-1-benzofuran-3-yl)-(3,4,5-trimethoxyphenyl)methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Wang, T, Wu, C, Pu, D.
登録日2019-08-15
公開日2020-08-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.74524117 Å)
主引用文献Unraveling the molecular mechanism of BNC105, a phase II clinical trial vascular disrupting agent, provides insights into drug design.
Biochem.Biophys.Res.Commun., 2020
2H3B
DownloadVisualize
BU of 2h3b by Molmil
Crystal Structure of Mouse Nicotinamide Phosphoribosyltransferase/Visfatin/Pre-B Cell Colony Enhancing Factor 1
分子名称: Nicotinamide phosphoribosyltransferase, SULFATE ION
著者Wang, T, Zhang, X, Bheda, P, Revollo, J.R, Imai, S.I, Wolberger, C.
登録日2006-05-22
公開日2006-06-20
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of Nampt/PBEF/visfatin, a mammalian NAD(+) biosynthetic enzyme.
Nat.Struct.Mol.Biol., 13, 2006
2H3D
DownloadVisualize
BU of 2h3d by Molmil
Crystal Structure of Mouse Nicotinamide Phosphoribosyltransferase/Visfatin/Pre-B Cell Colony Enhancing Factor in Complex with Nicotinamide Mononuleotide
分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide phosphoribosyltransferase
著者Wang, T, Zhang, X, Bheda, P, Revollo, J.R, Imai, S.I, Wolberger, C.
登録日2006-05-22
公開日2006-06-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of Nampt/PBEF/visfatin, a mammalian NAD(+) biosynthetic enzyme.
Nat.Struct.Mol.Biol., 13, 2006
2LI6
DownloadVisualize
BU of 2li6 by Molmil
1H, 13C, and 15N Chemical Shift Assignments for yeast protein
分子名称: SWI/SNF chromatin-remodeling complex subunit SWI1
著者Wang, T, Zhang, J, Tu, X.
登録日2011-08-24
公開日2012-04-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of SWI1 ARID domain from Saccharomyces cerevisiae and its non-specific binding to DNA
Proteins, 2012
2L7Y
DownloadVisualize
BU of 2l7y by Molmil
Solution structure of a putative surface protein
分子名称: Putative endo-beta-N-acetylglucosaminidase
著者Wang, T, Yuan, G, Zhang, J, Tu, X.
登録日2010-12-27
公開日2012-02-29
最終更新日2012-11-21
実験手法SOLUTION NMR
主引用文献1H and 15N Assigned Chemical Shifts for a putative surface protein
To be Published
7DYG
DownloadVisualize
BU of 7dyg by Molmil
Histone lysine demethylase 4D (KDM4D) in complex with the inhibitor 2-(1H-pyrazol-3-yl)isonicotinic acid
分子名称: 2-(1H-pyrazol-3-yl)pyridine-4-carboxylic acid, FE (III) ION, Lysine-specific demethylase 4D
著者Wang, T, Yang, L.
登録日2021-01-21
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of histone lysine demethylase 4D (KDM4D) in complex with the inhibitor 2-(1H-pyrazol-3-yl)isonicotinic acid
To Be Published
7DYQ
DownloadVisualize
BU of 7dyq by Molmil
Crystal structure of histone lysine demethylase 4D (KDM4D) in complex with the inhibitor 5-hydroxy-2-methylpyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile
分子名称: 5-hydroxy-2-methylpyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile, FE (III) ION, Lysine-specific demethylase 4D
著者Wang, T, Yang, L.
登録日2021-01-22
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Crystal structure of histone lysine demethylase 4D (KDM4D) in complex with the inhibitor 5-hydroxy-2-methylpyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile
To Be Published
5KWA
DownloadVisualize
BU of 5kwa by Molmil
complete structure of the Mycobacterium tuberculosis proteasomal ATPase Mpa
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Proteasome-associated ATPase
著者Wang, T, WU, Y.J.
登録日2016-07-17
公開日2017-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mycobacterium tuberculosis proteasomal ATPase Mpa has a beta-grasp domain that hinders docking with the proteasome core protease
Mol. Microbiol., 105, 2017
4LUQ
DownloadVisualize
BU of 4luq by Molmil
Crystal structure of virulence effector Tse3 in complex with neutralizer Tsi3
分子名称: CALCIUM ION, Uncharacterized protein
著者Wang, T, Li, L, Zhang, W.
登録日2013-07-25
公開日2013-09-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural Insights on the Bacteriolytic and Self-protection Mechanism of Muramidase Effector Tse3 in Pseudomonas aeruginosa
J.Biol.Chem., 288, 2013
7W5J
DownloadVisualize
BU of 7w5j by Molmil
The structure of trichobrasilenol synthase TaTC6 in complex with FPP-2
分子名称: FARNESYL, FARNESYL DIPHOSPHATE, GLYCEROL, ...
著者Chen, C, Wang, T, Yang, Y, Zhang, L, Ko, T, Huang, J, Guo, R.
登録日2021-11-30
公開日2022-06-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural insights into the cyclization of unusual brasilane-type sesquiterpenes.
Int.J.Biol.Macromol., 209, 2022
7W5G
DownloadVisualize
BU of 7w5g by Molmil
The apo structure of trichobrasilenol synthase TaTC6 with the space group of orthorhombic
分子名称: GLYCEROL, SULFATE ION, Terpene cyclase 6
著者Chen, C, Wang, T, Yang, Y, Zhang, L, Ko, T, Huang, J, Guo, R.
登録日2021-11-30
公開日2022-06-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the cyclization of unusual brasilane-type sesquiterpenes.
Int.J.Biol.Macromol., 209, 2022
7W5I
DownloadVisualize
BU of 7w5i by Molmil
The structure of trichobrasilenol synthase TaTC6 in complex with FPP-1
分子名称: FARNESYL DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Chen, C, Wang, T, Yang, Y, Zhang, L, Ko, T, Huang, J, Guo, R.
登録日2021-11-30
公開日2022-06-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural insights into the cyclization of unusual brasilane-type sesquiterpenes.
Int.J.Biol.Macromol., 209, 2022
7W5F
DownloadVisualize
BU of 7w5f by Molmil
The apo structure of trichobrasilenol synthase TaTC6 with the space group of monoclinic
分子名称: MAGNESIUM ION, Terpene cyclase 6
著者Chen, C, Wang, T, Yang, Y, Zhang, L, Ko, T, Huang, J, Guo, R.
登録日2021-11-30
公開日2022-06-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural insights into the cyclization of unusual brasilane-type sesquiterpenes.
Int.J.Biol.Macromol., 209, 2022
4DOX
DownloadVisualize
BU of 4dox by Molmil
Crystal Structure of Papaya mosaic virus capsid protein
分子名称: Coat protein
著者Wang, T, Li, H.
登録日2012-02-11
公開日2012-06-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the coat protein of the flexible filamentous papaya mosaic virus.
J.Mol.Biol., 422, 2012

218853

件を2024-04-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon