7SSZ
| Structure of human Kv1.3 with A0194009G09 nanobodies | Descriptor: | Nanobody A0194009G09, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion | Authors: | Meyerson, J.R, Selvakumar, P. | Deposit date: | 2021-11-11 | Release date: | 2022-06-29 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
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7SSV
| Structure of human Kv1.3 with Fab-ShK fusion | Descriptor: | Fab-ShK fusion, heavy chain, light chain, ... | Authors: | Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R. | Deposit date: | 2021-11-11 | Release date: | 2022-06-29 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
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7SSY
| Structure of human Kv1.3 (alternate conformation) | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion | Authors: | Meyerson, J.R, Selvakumar, P. | Deposit date: | 2021-11-11 | Release date: | 2022-06-29 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
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7SSX
| Structure of human Kv1.3 | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, Green fluorescent protein fusion | Authors: | Meyerson, J.R, Selvakumar, P. | Deposit date: | 2021-11-11 | Release date: | 2022-06-29 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
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7SMG
| Crystal structure of a (p)ppApp hydrolase from Bacteroides caccae | Descriptor: | (p)ppApp hydrolase, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Ahmad, S, Alexei, A.G, Tsang, K.K, Trilesky, S, Kim, Y, Whitney, J.C. | Deposit date: | 2021-10-25 | Release date: | 2022-11-09 | Last modified: | 2023-05-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp. Proc.Natl.Acad.Sci.USA, 120, 2023
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6II9
| Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L3A-44 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of L3A-44 Fab, Hemagglutinin, ... | Authors: | Jiang, H.H, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2018-10-03 | Release date: | 2018-10-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nat Microbiol, 4, 2019
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6II8
| Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4B-18 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of L4B-18 Fab, Hemagglutinin, ... | Authors: | Jiang, H.H, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2018-10-03 | Release date: | 2018-10-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nat Microbiol, 4, 2019
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7TOL
| X-ray crystal structure of glycerol dibiphytanyl glycerol tetraether - macrocyclic archaeol synthase (GDGT-MAS) from Methanocaldococcus jannaschii with archaeal lipid, 5'deoxyadenosine, and methionine bound | Descriptor: | 3-PHOSPHORYL-[1,2-DI-PHYTANYL]GLYCEROL, 3-[GLYCEROLYLPHOSPHONYL]-[1,2-DI-PHYTANYL]GLYCEROL, 5'-DEOXYADENOSINE, ... | Authors: | Lloyd, C.T, Booker, S.J, Boal, A.K. | Deposit date: | 2022-01-24 | Release date: | 2022-08-31 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Discovery, structure and mechanism of a tetraether lipid synthase. Nature, 609, 2022
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6II4
| Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4A-14 | Descriptor: | Heavy chain of L4A-14 Fab, Hemagglutinin, Light chain of L4A-14 Fab | Authors: | Jiang, H.H, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2018-10-03 | Release date: | 2018-10-24 | Last modified: | 2019-02-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nat Microbiol, 4, 2019
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7TOM
| X-ray crystal structure of glycerol dibiphytanyl glycerol tetraether - macrocyclic archaeol synthase (GDGT-MAS) from Methanocaldococcus jannaschii with bacterial lipid substrate analog, 5'deoxyadenosine, and methionine bound | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, 5'-DEOXYADENOSINE, FE (III) ION, ... | Authors: | Lloyd, C.T, Booker, S.J, Boal, A.K. | Deposit date: | 2022-01-24 | Release date: | 2022-08-31 | Last modified: | 2022-09-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Discovery, structure and mechanism of a tetraether lipid synthase. Nature, 609, 2022
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2MS0
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7TDQ
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2MQT
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2MS1
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7Y9J
| Crystal structure of P450 BM3-TMK from Bacillus megaterium in complex with 5-nitro-1,2-benzisoxazole | Descriptor: | 5-nitro-1,2-benzoxazole, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-06-24 | Release date: | 2023-06-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Engineering of a P450-based Kemp eliminase with a new mechanism Chinese J Catal, 47, 2023
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7Y9K
| Crystal structure of P450 BM3-TMK from Bacillus megaterium | Descriptor: | Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-06-25 | Release date: | 2023-06-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Engineering of a P450-based Kemp eliminase with a new mechanism Chinese J Catal, 47, 2023
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7TWD
| Structure of AAGAB C-terminal dimerization domain | Descriptor: | Alpha- and gamma-adaptin-binding protein p34, PHOSPHATE ION | Authors: | Tian, Y, Yin, Q. | Deposit date: | 2022-02-07 | Release date: | 2023-01-18 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Oligomer-to-monomer transition underlies the chaperone function of AAGAB in AP1/AP2 assembly. Proc.Natl.Acad.Sci.USA, 120, 2023
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7URA
| Human PORCN in complex with Palmitoleoyl-CoA | Descriptor: | 2C11 heavy chain, 2C11 light chain, CHOLESTEROL, ... | Authors: | Liu, Y, Qi, X, Li, X. | Deposit date: | 2022-04-21 | Release date: | 2022-07-20 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature, 607, 2022
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7URD
| Human PORCN in complex with LGK974 and WNT3A peptide | Descriptor: | 2-[(2P)-2',3-dimethyl[2,4'-bipyridin]-5-yl]-N-[(5P)-5-(pyrazin-2-yl)pyridin-2-yl]acetamide, 2C11 heavy chain, 2C11 light chain, ... | Authors: | Liu, Y, Qi, X, Li, X. | Deposit date: | 2022-04-21 | Release date: | 2022-07-20 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature, 607, 2022
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7URF
| Human HHAT H379C in complex with SHH N-terminal peptide | Descriptor: | 3H02 heavy chain, 3H02 light chain, Digitonin, ... | Authors: | Liu, Y, Qi, X, Li, X. | Deposit date: | 2022-04-21 | Release date: | 2022-07-20 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature, 607, 2022
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7URE
| Human PORCN in complex with palmitoleoylated WNT3A peptide | Descriptor: | 2C11 heavy chain, 2C11 light chain, Digitonin, ... | Authors: | Liu, Y, Qi, X, Li, X. | Deposit date: | 2022-04-21 | Release date: | 2022-07-20 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature, 607, 2022
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7URC
| Human PORCN in complex with LGK974 | Descriptor: | 2-[(2P)-2',3-dimethyl[2,4'-bipyridin]-5-yl]-N-[(5P)-5-(pyrazin-2-yl)pyridin-2-yl]acetamide, 2C11 heavy chain, 2C11 light chain, ... | Authors: | Liu, Y, Qi, X, Li, X. | Deposit date: | 2022-04-21 | Release date: | 2022-07-20 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature, 607, 2022
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6KJ7
| E. coli ATCase catalytic subunit mutant - G166P | Descriptor: | Aspartate carbamoyltransferase catalytic subunit | Authors: | Lei, Z, Zheng, J, Jia, Z. | Deposit date: | 2019-07-21 | Release date: | 2020-03-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.839 Å) | Cite: | New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development. Febs J., 287, 2020
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6KJ9
| E. coli ATCase catalytic subunit mutant - G128/130A | Descriptor: | Aspartate carbamoyltransferase catalytic subunit | Authors: | Lei, Z, Zheng, J, Jia, Z.C. | Deposit date: | 2019-07-22 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development. Febs J., 287, 2020
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6KJ8
| E. coli ATCase holoenzyme mutant - G166P (catalytic chain) | Descriptor: | Aspartate carbamoyltransferase catalytic subunit, Aspartate carbamoyltransferase regulatory chain, ZINC ION | Authors: | Lei, Z, Zheng, J, Jia, Z.C. | Deposit date: | 2019-07-22 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.011 Å) | Cite: | New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development. Febs J., 287, 2020
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