7URA

Human PORCN in complex with Palmitoleoyl-CoA

Summary for 7URA

• Entry DOI: 10.2210/pdb7ura/pdb
• EMDB information: 26707
• Descriptor: Isoform 2 of Protein-serine O-palmitoleoyltransferase porcupine, 2C11 light chain, 2C11 heavy chain, ... (8 entities in total)
• Functional Keywords: coa-bound, complex, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 108785.90

Authors

Liu, Y.,Qi, X.,Li, X. (deposition date: 2022-04-21, release date: 2022-07-20, Last modification date: 2022-08-10)

• Primary citation: Liu, Y.,Qi, X.,Donnelly, L.,Elghobashi-Meinhardt, N.,Long, T.,Zhou, R.W.,Sun, Y.,Wang, B.,Li, X.; Mechanisms and inhibition of Porcupine-mediated Wnt acylation.; Nature, 607:816-822, 2022; PubMed: 35831507; DOI: 10.1038/s41586-022-04952-2

Experimental method

ELECTRON MICROSCOPY (3.11 Å)