7URA
Human PORCN in complex with Palmitoleoyl-CoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 2 of Protein-serine O-palmitoleoyltransferase porcupine | polymer | 464 | 52824.7 | 1 | UniProt (Q9H237) Pfam (PF03062) | Homo sapiens (human) | Protein MG61 |
| 2 | B (L) | 2C11 light chain | polymer | 234 | 25673.7 | 1 | Mus musculus (Mouse) | ||
| 3 | C (H) | 2C11 heavy chain | polymer | 250 | 26933.1 | 1 | Mus musculus (Mouse) | ||
| 4 | D (A) | ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (~{Z})-hexadec-9-enethioate | non-polymer | 1003.9 | 1 | Chemie (OH6) | |||
| 5 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | F, G (A) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) | |||
| 7 | H (A) | Digitonin | non-polymer | 1229.3 | 1 | Chemie (AJP) | |||
| 8 | I (A) | OLEIC ACID | non-polymer | 282.5 | 1 | Chemie (OLA) |
Sequence modifications
A: 2 - 456 (UniProt: Q9H237)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Asp -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Lys -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Lys 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 105431.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3354.4 | |
| All* | Total formula weight | 108785.9 |
