6KJ9

E. coli ATCase catalytic subunit mutant - G128/130A

Summary for 6KJ9

Entry DOI	10.2210/pdb6kj9/pdb
Descriptor	Aspartate carbamoyltransferase catalytic subunit (2 entities in total)
Functional Keywords	aspartate transcarbamoylase catalytic subunit, de novo pyrimidine biosynthesis, transferase
Biological source	Escherichia coli K-12
Total number of polymer chains	6
Total formula weight	206190.94
Authors	Lei, Z.,Zheng, J.,Jia, Z.C. (deposition date: 2019-07-22, release date: 2020-03-11, Last modification date: 2023-11-22)
Primary citation	Lei, Z.,Wang, B.,Lu, Z.,Wang, N.,Tan, H.,Zheng, J.,Jia, Z. New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development. Febs J., 287:3579-3599, 2020 Cited by PubMed: 31967710 DOI: 10.1111/febs.15220 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation