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CRYSTALLOGRAPHIC ANALYSIS OF THE CATALYTIC MECHANISM OF HALOALKANE DEHALOGENASE
分子名称:	CHLORIDE ION, HALOALKANE DEHALOGENASE
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-09-08
公開日	1994-07-31
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.13 Å)
主引用文献	Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase. Nature, 363, 1993

2DHC

CRYSTALLOGRAPHIC ANALYSIS OF THE CATALYTIC MECHANISM OF HALOALKANE DEHALOGENASE
分子名称:	1,2-DICHLOROETHANE, HALOALKANE DEHALOGENASE
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-09-08
公開日	1994-07-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase. Nature, 363, 1993

2EDC

CRYSTALLOGRAPHIC AND FLUORESCENCE STUDIES OF THE INTERACTION OF HALOALKANE DEHALOGENASE WITH HALIDE IONS: STUDIES WITH HALIDE COMPOUNDS REVEAL A HALIDE BINDING SITE IN THE ACTIVE SITE
分子名称:	HALOALKANE DEHALOGENASE, IODIDE ION
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-08-31
公開日	1994-01-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry, 32, 1993

2EDA

CRYSTALLOGRAPHIC AND FLUORESCENCE STUDIES OF THE INTERACTION OF HALOALKANE DEHALOGENASE WITH HALIDE IONS: STUDIES WITH HALIDE COMPOUNDS REVEAL A HALIDE BINDING SITE IN THE ACTIVE SITE
分子名称:	HALOALKANE DEHALOGENASE, IODIDE ION
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-08-30
公開日	1993-10-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.19 Å)
主引用文献	Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry, 32, 1993

6HXH

Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP
分子名称:	ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase,Human ATP citrate lyase, CITRATE ANION, ...
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (3.3 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXI

Structure of ATP citrate lyase from Methanothrix soehngenii in complex with citrate and coenzyme A
分子名称:	ACETATE ION, CITRATE ANION, COENZYME A, ...
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXL

Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH (space group P21)
分子名称:	1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.35 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXO

Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P21)
分子名称:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ATP-citrate lyase alpha-subunit, CITRATE ANION
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXP

Structure of citryl-CoA lyase from Hydrogenobacter thermophilus
分子名称:	COENZYME A, Citryl-CoA lyase, SULFATE ION
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.45 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXJ

Structure of ATP citrate lyase from Chlorobium limicola in complex with citrate and coenzyme A.
分子名称:	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-citrate lyase alpha-subunit, ATP-citrate lyase beta-subunit, ...
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (2.58 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXN

Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P3121)
分子名称:	ATP-citrate lyase alpha-subunit, COENZYME A, SULFATE ION
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXQ

Structure of citryl-CoA synthetase from Hydrogenobacter thermophilus
分子名称:	CITRATE ANION, COENZYME A, Citryl-CoA synthetase large subunit, ...
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (2.91 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXK

Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate
分子名称:	1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXM

Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221
分子名称:	ATP-citrate synthase, CITRATE ANION, COENZYME A
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.3 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

2HAD

CRYSTAL STRUCTURE OF HALOALKANE DEHALOGENASE: AN ENZYME TO DETOXIFY HALOGENATED ALKANES
分子名称:	HALOALKANE DEHALOGENASE
著者	Verschueren, K.H.G, Franken, S.M, Dijkstra, B.W.
登録日	1992-08-07
公開日	1993-01-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Crystal structure of haloalkane dehalogenase: an enzyme to detoxify halogenated alkanes. EMBO J., 10, 1991

7Z3P

Crystal structure of the mouse leptin:LepR-CRH2 encounter complex to 1.95 A resolution.
分子名称:	CALCIUM ION, DI(HYDROXYETHYL)ETHER, Leptin, ...
著者	Tsirigotaki, A, Verschueren, K, Savvides, S.N, Verstraete, K.
登録日	2022-03-02
公開日	2023-03-22
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.943 Å)
主引用文献	Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023

7Z3R

Crystal structure of the mouse leptin:LepR-IgCRH2 complex to 2.95 A resolution.
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
著者	Verstraete, K, Verschueren, K, Savvides, S.N, Tsirigotaki, A.
登録日	2022-03-02
公開日	2023-03-22
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.951 Å)
主引用文献	Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023

7Z3Q

Crystal structure of the human leptin:LepR-CRH2 encounter complex to 3.6 A resolution.
分子名称:	Leptin, Leptin receptor
著者	Verstraete, K, Verschueren, K, Alexandra, T, Savvides, S.N.
登録日	2022-03-02
公開日	2023-03-22
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (3.617 Å)
主引用文献	Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023

7RDH

Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ...
著者	Kadam, R.U, Wilson, I.A.
登録日	2021-07-09
公開日	2022-05-04
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.75 Å)
主引用文献	Design of protein-binding proteins from the target structure alone. Nature, 605, 2022

7S5B

Unbound State of a De novo designed Protein Binder to the Human Interleukin-7 Receptor
分子名称:	Miniprotein Binder
著者	Walsh, S.T.R, Cao, L, Baker, D.
登録日	2021-09-10
公開日	2022-05-11
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Design of protein-binding proteins from the target structure alone. Nature, 605, 2022

7N1J

Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder
分子名称:	Binder, Fibroblast growth factor receptor 4
著者	Park, J.S, Lee, S.
登録日	2021-05-27
公開日	2022-04-06
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.99 Å)
主引用文献	Design of protein-binding proteins from the target structure alone. Nature, 605, 2022

7N1K

Crystal structure of a de novo-designed mini-protein targeting FGFR
分子名称:	Binder
著者	Park, J.S, Lee, S.
登録日	2021-05-27
公開日	2022-04-06
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (3.01 Å)
主引用文献	Design of protein-binding proteins from the target structure alone. Nature, 605, 2022

7N3T

TrkA ECD complex with designed miniprotein ligand
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Jude, K.M, Cao, L, Garcia, K.C.
登録日	2021-06-01
公開日	2022-04-20
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.84 Å)
主引用文献	Design of protein-binding proteins from the target structure alone. Nature, 605, 2022

8AV2

Crystal structure for the FnIII module of mouse LEP-R in complex with the anti-LEP-R nanobody VHH-4.80
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin receptor, SULFATE ION, ...
著者	Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日	2022-08-26
公開日	2023-04-05
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023

8B7Q

Cryo-EM structure for the mouse LEPR-CRH2:Leptin:LEPR-Ig complex following symmetry expansion in combination with local refinement
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
著者	Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日	2022-09-30
公開日	2023-04-05
最終更新日	2023-04-26
実験手法	ELECTRON MICROSCOPY (4.02 Å)
主引用文献	Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023

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