6HT5
| Oct4/Sox2:UTF1 structure | Descriptor: | DNA (5'-D(*TP*TP*CP*AP*CP*TP*AP*GP*CP*AP*TP*AP*AP*CP*AP*AP*TP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*CP*AP*TP*TP*GP*TP*TP*AP*TP*GP*CP*TP*AP*GP*TP*GP*AP*AP*G)-3'), POU domain, ... | Authors: | Vahokoski, J, Meusch, D, Groves, M, Pogenberg, V, Wilmanns, M. | Deposit date: | 2018-10-03 | Release date: | 2019-10-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.451 Å) | Cite: | Oct4/Sox2:UTF1 structure To Be Published
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6TU4
| Structure of Plasmodium Actin1 filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ... | Authors: | Vahokoski, J, Calder, L.J, Lopez, A.J, Rosenthal, P.B, Kursula, I. | Deposit date: | 2020-01-02 | Release date: | 2021-01-13 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | High-resolution structures of malaria parasite actomyosin and actin filaments. Plos Pathog., 18, 2022
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6TU7
| Structure of PfMyoA decorated Plasmodium Act1 filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ... | Authors: | Vahokoski, J, Calder, L.J, Lopez, A.J, Rosenthal, P.B, Kursula, I. | Deposit date: | 2020-01-03 | Release date: | 2021-01-13 | Last modified: | 2024-11-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | High-resolution structures of malaria parasite actomyosin and actin filaments. Plos Pathog., 18, 2022
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4CBW
| Crystal structure of Plasmodium berghei actin I with D-loop from muscle actin | Descriptor: | 1,4-DIETHYLENE DIOXIDE, ACTIN, ALPHA SKELETAL MUSCLE, ... | Authors: | Vahokoski, J, Bhargav, S.P, Desfosses, A, Andreadaki, M, Kumpula, E.P, Ignatev, A, Munico Martinez, S, Lepper, S, Frischknecht, F, Siden-Kiamos, I, Sachse, C, Kursula, I. | Deposit date: | 2013-10-17 | Release date: | 2014-04-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structural Differences Explain Diverse Functions of Plasmodium Actins. Plos Pathog., 10, 2014
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4CBU
| Crystal structure of Plasmodium falciparum actin I | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-1, CALCIUM ION, ... | Authors: | Vahokoski, J, Bhargav, S.P, Desfosses, A, Andreadaki, M, Kumpula, E.P, Ignatev, A, Munico Martinez, S, Lepper, S, Frischknecht, F, Siden-Kiamos, I, Sachse, C, Kursula, I. | Deposit date: | 2013-10-16 | Release date: | 2014-04-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural Differences Explain Diverse Functions of Plasmodium Actins. Plos Pathog., 10, 2014
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4CBX
| Crystal structure of Plasmodium berghei actin II | Descriptor: | ACTIN-2, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Vahokoski, J, Bhargav, S.P, Desfosses, A, Andreadaki, M, Kumpula, E.P, Ignatev, A, Munico Martinez, S, Lepper, S, Frischknecht, F, Siden-Kiamos, I, Sachse, C, Kursula, I. | Deposit date: | 2013-10-17 | Release date: | 2014-04-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Differences Explain Diverse Functions of Plasmodium Actins. Plos Pathog., 10, 2014
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3L1P
| POU protein:DNA complex | Descriptor: | DNA (5'-D(*AP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP*TP*CP*AP*AP*AP*TP*GP*TP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP*CP*AP*AP*AP*TP*GP*GP*A)-3'), POU domain, ... | Authors: | Vahokoski, J, Groves, M.R, Pogenberg, V, Wilmanns, M. | Deposit date: | 2009-12-14 | Release date: | 2010-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A unique Oct4 interface is crucial for reprogramming to pluripotency Nat.Cell Biol., 15, 2013
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1YRP
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1YR5
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5OGW
| Cryo-EM structure of jasplakinolide-stabilized malaria parasite F-actin at near-atomic resolution | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ... | Authors: | Pospich, S, Kumpula, E.-P, von der Ecken, J, Vahokoski, J, Kursula, I, Raunser, S. | Deposit date: | 2017-07-13 | Release date: | 2017-09-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1WRZ
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1ZUZ
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3KNB
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4D60
| Structure of a dimeric Plasmodium falciparum profilin mutant | Descriptor: | PROFILIN, SULFATE ION | Authors: | Bhargav, S.P, Vahokoski, J, Kallio, J.P, Torda, A, Kursula, P, Kursula, I. | Deposit date: | 2014-11-07 | Release date: | 2015-06-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Two Independently Folding Units of Plasmodium Profilin Suggest Evolution Via Gene Fusion. Cell.Mol.Life Sci., 72, 2015
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2XZS
| Death associated protein kinase 1 residues 1-312 | Descriptor: | DEATH ASSOCIATED KINASE 1, MAGNESIUM ION | Authors: | Yumerefendi, H, Mas, P.J, Dordevic, N, McCarthy, A.A, Hart, D.J. | Deposit date: | 2010-11-29 | Release date: | 2011-12-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Death-Associated Protein Kinase Activity is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites. Structure, 24, 2016
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2K0J
| Solution structure of CaM complexed to DRP1p | Descriptor: | CALCIUM ION, LANTHANUM (III) ION, calmodulin | Authors: | Bertini, I, Luchinat, C, Parigi, G, Yuan, J, Structural Proteomics in Europe (SPINE) | Deposit date: | 2008-02-04 | Release date: | 2009-03-10 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Accurate solution structures of proteins from X-ray data and a minimal set of NMR data: calmodulin-peptide complexes as examples. J.Am.Chem.Soc., 131, 2009
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2K61
| Solution structure of CaM complexed to DAPk peptide | Descriptor: | CALCIUM ION, Calmodulin, TERBIUM(III) ION | Authors: | Bertini, I, Luchinat, C, Parigi, G, Yuan, J. | Deposit date: | 2008-07-02 | Release date: | 2009-05-05 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Accurate solution structures of proteins from X-ray data and a minimal set of NMR data: calmodulin-peptide complexes as examples. J.Am.Chem.Soc., 131, 2009
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8E6K
| 2H08 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2H08 fragment antigen binding heavy chain, 2H08 fragment antigen binding light chain, ... | Authors: | Turner, H.L, Ozorowski, G, Ward, A.B. | Deposit date: | 2022-08-22 | Release date: | 2023-08-09 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
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8E6J
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8EQA
| Crystal structure of human anti-N1 neuraminidase 2H08 Fab | Descriptor: | 2H08 Fab heavy chain, 2H08 Fab light chain, ZINC ION | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2022-10-07 | Release date: | 2023-08-09 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
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8EQC
| Crystal structure of human anti-N1 neuraminidase 3H03 Fab | Descriptor: | 3H03 Fab heavy chain, 3H03 Fab light chain, PHOSPHATE ION | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2022-10-07 | Release date: | 2023-08-09 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
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8CCN
| Filamentous actin II from Plasmodium falciparum | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-2, MAGNESIUM ION | Authors: | Kursula, I, Lopez, A.J. | Deposit date: | 2023-01-27 | Release date: | 2023-02-22 | Last modified: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure and function of Plasmodium actin II in the parasite mosquito stages. Plos Pathog., 19, 2023
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8CCO
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2A2A
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4F14
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