5OGW

Cryo-EM structure of jasplakinolide-stabilized malaria parasite F-actin at near-atomic resolution

Summary for 5OGW

Entry DOI	10.2210/pdb5ogw/pdb
EMDB information	3805
Descriptor	Actin-1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	f-actin, plasmodium, malaria parasite, cytoskeleton, cryo-em, jas, jasplakinolide, filament, glideosome, gliding motility, thin filament, structural protein
Biological source	Plasmodium falciparum (isolate HB3)
Total number of polymer chains	5
Total formula weight	214624.92
Authors	Pospich, S.,Kumpula, E.-P.,von der Ecken, J.,Vahokoski, J.,Kursula, I.,Raunser, S. (deposition date: 2017-07-13, release date: 2017-09-27, Last modification date: 2022-11-09)
Primary citation	Pospich, S.,Kumpula, E.P.,von der Ecken, J.,Vahokoski, J.,Kursula, I.,Raunser, S. Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability. Proc. Natl. Acad. Sci. U.S.A., 114:10636-10641, 2017 Cited by PubMed: 28923924 DOI: 10.1073/pnas.1707506114 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation