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5OGW

Cryo-EM structure of jasplakinolide-stabilized malaria parasite F-actin at near-atomic resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Actin-1polymer37842047.75UniProt (P86287)
Pfam (PF00022)
UniProt (by SIFTS) (Q8I4X0)
Plasmodium falciparum (isolate HB3)Actin I,PfACT1
2F, I, K, N, P
(A, B, C, D, E)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.25Chemie (ADP)
3G, J, L, O, Q
(A, B, C, D, E)
MAGNESIUM IONnon-polymer24.35Chemie (MG)
4H, M, R
(A, C, E)
Jasplakinolidenon-polymer709.73Chemie (9UE)
Sequence modifications
A, B, C, D, E: 3 - 378 (UniProt: P86287)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ala 2-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight210238.4
Non-Polymers*Number of molecules13
Total formula weight4386.5
All*Total formula weight214624.9
*Water molecules are not included.

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PDB entries from 2025-12-24

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