8E6K

2H08 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)

Summary for 8E6K

Entry DOI	10.2210/pdb8e6k/pdb
EMDB information	27921
Descriptor	Neuraminidase, 2H08 fragment antigen binding light chain, 2H08 fragment antigen binding heavy chain, ... (4 entities in total)
Functional Keywords	influenza, monoclonal antibody, na, h1n1, cross-reactive antibody, viral protein
Biological source	Influenza A virus (A/Brevig Mission/1/1918(H1N1)) More
Total number of polymer chains	12
Total formula weight	389421.99
Authors	Turner, H.L.,Ozorowski, G.,Ward, A.B. (deposition date: 2022-08-22, release date: 2023-08-09, Last modification date: 2023-08-23)
Primary citation	Hansen, L.,McMahon, M.,Turner, H.L.,Zhu, X.,Turner, J.S.,Ozorowski, G.,Stadlbauer, D.,Vahokoski, J.,Schmitz, A.J.,Rizk, A.A.,Alsoussi, W.B.,Strohmeier, S.,Yu, W.,Choreno-Parra, J.A.,Jimenez-Alvarez, L.,Cruz-Lagunas, A.,Zuniga, J.,Mudd, P.A.,Cox, R.J.,Wilson, I.A.,Ward, A.B.,Ellebedy, A.H.,Krammer, F. Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56:1927-1938.e8, 2023 Cited by PubMed: 37506693 DOI: 10.1016/j.immuni.2023.07.004 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation