8E6K
2H08 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, B, C, D) | Neuraminidase | polymer | 449 | 49726.4 | 4 | UniProt (Q9IGQ6) Pfam (PF00064) | Influenza A virus (A/Brevig Mission/1/1918(H1N1)) | |
| 2 | B, E, H, K (L, I, J, K) | 2H08 fragment antigen binding light chain | polymer | 215 | 23543.1 | 4 | Homo sapiens (human) | ||
| 3 | C, F, I, L (H, E, F, G) | 2H08 fragment antigen binding heavy chain | polymer | 225 | 23864.8 | 4 | Homo sapiens (human) | ||
| 4 | M, N, O, P (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A, B, C, D: 82 - 470 (UniProt: Q9IGQ6)
| PDB | External Database | Details |
|---|---|---|
| Ala 21 | - | expression tag |
| Asp 22 | - | expression tag |
| Pro 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
| His 26 | - | expression tag |
| His 27 | - | expression tag |
| His 28 | - | expression tag |
| His 29 | - | expression tag |
| Ser 30 | - | expression tag |
| Ser 31 | - | expression tag |
| Ser 32 | - | expression tag |
| Asp 33 | - | expression tag |
| Tyr 34 | - | expression tag |
| Ser 35 | - | expression tag |
| Asp 36 | - | expression tag |
| Leu 37 | - | expression tag |
| Gln 38 | - | expression tag |
| Arg 39 | - | expression tag |
| Val 40 | - | expression tag |
| Lys 41 | - | expression tag |
| Gln 42 | - | expression tag |
| Glu 43 | - | expression tag |
| Leu 44 | - | expression tag |
| Leu 45 | - | expression tag |
| Glu 46 | - | expression tag |
| Glu 47 | - | expression tag |
| Val 48 | - | expression tag |
| Lys 49 | - | expression tag |
| Lys 50 | - | expression tag |
| Glu 51 | - | expression tag |
| Leu 52 | - | expression tag |
| Gln 53 | - | expression tag |
| Lys 54 | - | expression tag |
| Val 55 | - | expression tag |
| Lys 56 | - | expression tag |
| Glu 57 | - | expression tag |
| Glu 58 | - | expression tag |
| Ile 59 | - | expression tag |
| Ile 60 | - | expression tag |
| Glu 61 | - | expression tag |
| Ala 62 | - | expression tag |
| Phe 63 | - | expression tag |
| Val 64 | - | expression tag |
| Gln 65 | - | expression tag |
| Glu 66 | - | expression tag |
| Leu 67 | - | expression tag |
| Arg 68 | - | expression tag |
| Lys 69 | - | expression tag |
| Arg 70 | - | expression tag |
| Gly 71 | - | expression tag |
| Ser 72 | - | expression tag |
| Leu 73 | - | expression tag |
| Val 74 | - | expression tag |
| Pro 75 | - | expression tag |
| Arg 76 | - | expression tag |
| Gly 77 | - | expression tag |
| Ser 78 | - | expression tag |
| Pro 79 | - | expression tag |
| Ser 80 | - | expression tag |
| Arg 81 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 388537.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 389422.0 |
