4F14

Structure of the SH3 domain of human nebulette in complex with a peptide of XIRP2

Summary for 4F14

Entry DOI	10.2210/pdb4f14/pdb
Descriptor	Nebulette, Xin actin-binding repeat-containing protein 2, ZINC ION, ... (4 entities in total)
Functional Keywords	sh3 domain, heart muscle, actin-binding protein-peptide complex, actin-binding protein/peptide
Biological source	Homo sapiens (human) More
Cellular location	Isoform 2: Cytoplasm : O76041 Cell junction : A4UGR9
Total number of polymer chains	2
Total formula weight	8873.28
Authors	Sauer, F.,Vahokoski, J.,Wilmanns, M. (deposition date: 2012-05-06, release date: 2012-06-20, Last modification date: 2024-02-28)
Primary citation	Eulitz, S.,Sauer, F.,Pelissier, M.C.,Boisguerin, P.,Molt, S.,Schuld, J.,Orfanos, Z.,Kley, R.A.,Volkmer, R.,Wilmanns, M.,Kirfel, G.,van der Ven, P.F.,Furst, D.O. Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling. Mol Biol Cell, 24:3215-3226, 2013 Cited by PubMed: 23985323 DOI: 10.1091/mbc.E13-04-0202 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation