4XGX
 
 | | Crystal structure of Escherichia coli Flavin trafficking protein, an FMN transferase, Y60N mutant, ADP-inhibited | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FAD:protein FMN transferase, ... | | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | | 登録日 | 2015-01-02 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm.
Microbiologyopen, 5, 2016
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4XDR
 | | Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, a bifunctional FMN transferase/FAD pyrophosphatase, D284A mutant, ADN bound form | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE, ... | | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | | 登録日 | 2014-12-19 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein.
Mbio, 6, 2015
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4XGW
 | | Crystal structure of Escherichia coli Flavin trafficking protein, an FMN transferase, E169K mutant | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, FAD:protein FMN transferase, ... | | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | | 登録日 | 2015-01-02 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | | 主引用文献 | Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm.
Microbiologyopen, 5, 2016
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6ANJ
 | | Synaptotagmin-7, C2A domain | | 分子名称: | ACETATE ION, CALCIUM ION, Synaptotagmin-7, ... | | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | | 登録日 | 2017-08-13 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6AO5
 | | Crystal structure of human MST2 in complex with SAV1 SARAH domain | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein salvador homolog 1, ... | | 著者 | Tomchick, D.R, Luo, X, Ni, L. | | 登録日 | 2017-08-15 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.955 Å) | | 主引用文献 | SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife, 6, 2017
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6ANK
 | | Synaptotagmin-7, C2A- and C2B-domains | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7 | | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | | 登録日 | 2017-08-13 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.254 Å) | | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4DBB
 | | The PTB domain of Mint1 is autoinhibited by a helix in the C-terminal linker region | | 分子名称: | ACETIC ACID, Amyloid beta A4 precursor protein-binding family A member 1, CHLORIDE ION, ... | | 著者 | Tomchick, D.R, Rizo, J, Ho, A, Xu, Y. | | 登録日 | 2012-01-13 | | 公開日 | 2012-03-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3SWH
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3U64
 | | The Crystal Structure of Tat-T (Tp0956) | | 分子名称: | Protein TP_0956, SULFATE ION | | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | | 登録日 | 2011-10-12 | | 公開日 | 2012-02-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural, Bioinformatic, and In Vivo Analyses of Two Treponema pallidum Lipoproteins Reveal a Unique TRAP Transporter.
J.Mol.Biol., 416, 2012
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3V5Z
 | | Structure of FBXL5 hemerythrin domain, C2 cell, grown anaerobically | | 分子名称: | F-box/LRR-repeat protein 5, MU-OXO-DIIRON | | 著者 | Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A. | | 登録日 | 2011-12-17 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1847 Å) | | 主引用文献 | Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5).
J.Biol.Chem., 287, 2012
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3V5Y
 | | Structure of FBXL5 hemerythrin domain, P2(1) cell | | 分子名称: | F-box/LRR-repeat protein 5, MU-OXO-DIIRON | | 著者 | Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A. | | 登録日 | 2011-12-17 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5).
J.Biol.Chem., 287, 2012
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3V5X
 | | Structure of FBXL5 hemerythrin domain, C2 cell | | 分子名称: | F-box/LRR-repeat protein 5, MU-OXO-DIIRON | | 著者 | Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A. | | 登録日 | 2011-12-17 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5).
J.Biol.Chem., 287, 2012
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3BEN
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3L15
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3KY9
 | | Autoinhibited Vav1 | | 分子名称: | Proto-oncogene vav, ZINC ION | | 著者 | Tomchick, D.R, Rosen, M.K, Machius, M, Yu, B. | | 登録日 | 2009-12-04 | | 公開日 | 2010-02-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.731 Å) | | 主引用文献 | Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1
Cell(Cambridge,Mass.), 140, 2010
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5UF7
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5UE8
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8VTS
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8VTT
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6VVC
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6VVE
 | | Legionella pneumophila Lpg2603 kinase bound to IP6, Mn2+, and ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Dot/Icm T4SS effector, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Tomchick, D.R, Tagliabracci, V.S, Park, B.C. | | 登録日 | 2020-02-17 | | 公開日 | 2020-04-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | ALegionellaeffector kinase is activated by host inositol hexakisphosphate.
J.Biol.Chem., 295, 2020
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6VVD
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4M63
 | | Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | | 著者 | Tomchick, D.R, Zahm, J.A, Rosen, M.K. | | 登録日 | 2013-08-08 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.748 Å) | | 主引用文献 | The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
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6DFT
 | | Trypanosoma brucei deoxyhypusine synthase | | 分子名称: | Deoxyhypusine synthase, Deoxyhypusine synthase regulatory subunit, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Tomchick, D.R, Phillips, M.A, Afanador, G.A. | | 登録日 | 2018-05-15 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Trypanosomatid Deoxyhypusine Synthase Activity Is Dependent on Shared Active-Site Complementation between Pseudoenzyme Paralogs.
Structure, 26, 2018
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6E0B
 | | Plasmodium falciparum dihydroorotate dehydrogenase C276F mutant bound with triazolopyrimidine-based inhibitor DSM1 | | 分子名称: | 5-methyl-7-(naphthalen-2-ylamino)-1H-[1,2,4]triazolo[1,5-a]pyrimidine-3,8-diium, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | | 著者 | Tomchick, D.R, Phillips, M.A, Deng, X. | | 登録日 | 2018-07-06 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265.
ACS Infect Dis, 5, 2019
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