3BEN
Structure of N-(12-imidazolyl-dodecanoyl)-L-leucine inhibitor bound to the heme domain of Cytochrome P450-BM3
Summary for 3BEN
Entry DOI | 10.2210/pdb3ben/pdb |
Related | 1BU7 1JPZ |
Descriptor | Cytochrome P450 102, PROTOPORPHYRIN IX CONTAINING FE, N-[12-(1H-imidazol-1-yl)dodecanoyl]-L-leucine, ... (6 entities in total) |
Functional Keywords | protein-substrate complex, hemeprotein, electron transport, fad, flavoprotein, fmn, iron, membrane, metal-binding, monooxygenase, multifunctional enzyme, nadp, oxidoreductase, transport |
Biological source | Bacillus megaterium |
Cellular location | Cytoplasm (By similarity): P14779 |
Total number of polymer chains | 2 |
Total formula weight | 109553.92 |
Authors | Tomchick, D.R. (deposition date: 2007-11-19, release date: 2008-09-30, Last modification date: 2023-08-30) |
Primary citation | Haines, D.C.,Chen, B.,Tomchick, D.R.,Bondlela, M.,Hegde, A.,Machius, M.,Peterson, J.A. Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel. Biochemistry, 47:3662-3670, 2008 Cited by PubMed: 18298086DOI: 10.1021/bi7023964 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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