6DFT

Trypanosoma brucei deoxyhypusine synthase

Summary for 6DFT

Entry DOI	10.2210/pdb6dft/pdb
Descriptor	Deoxyhypusine synthase, Deoxyhypusine synthase regulatory subunit, SODIUM ION, ... (4 entities in total)
Functional Keywords	heterotetramer, rossman fold, pseudoenzyme, nad+, transferase
Biological source	Trypanosoma brucei More
Total number of polymer chains	12
Total formula weight	533856.78
Authors	Tomchick, D.R.,Phillips, M.A.,Afanador, G.A. (deposition date: 2018-05-15, release date: 2018-08-08, Last modification date: 2023-10-11)
Primary citation	Afanador, G.A.,Tomchick, D.R.,Phillips, M.A. Trypanosomatid Deoxyhypusine Synthase Activity Is Dependent on Shared Active-Site Complementation between Pseudoenzyme Paralogs. Structure, 26:1499-1512.e5, 2018 Cited by PubMed: 30197036 DOI: 10.1016/j.str.2018.07.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation