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1NPE
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BU of 1npe by Molmil
Crystal structure of Nidogen/Laminin Complex
Descriptor: CADMIUM ION, Laminin gamma-1 chain, nidogen
Authors:Takagi, J, Yang, Y.T, Liu, J.-H, Wang, J.-H, Springer, T.A.
Deposit date:2003-01-17
Release date:2003-08-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface
Nature, 424, 2003
7NXD
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BU of 7nxd by Molmil
Cryo-EM structure of human integrin alpha5beta1 in the half-bent conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N.
Deposit date:2021-03-18
Release date:2021-08-25
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
7NWL
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BU of 7nwl by Molmil
Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-5, ...
Authors:Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N.
Deposit date:2021-03-17
Release date:2021-06-02
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
9IUT
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BU of 9iut by Molmil
Crystal structure of cancer-specific anti-HER2 antibody H2Mab-250 in complex with epitope peptide
Descriptor: H2Mab-250 VH(S112C)-SARAH, H2Mab-250 VL-SARAH(S37C), H2Mab-250 epitope peptide
Authors:Arimori, T, Takagi, J.
Deposit date:2024-07-22
Release date:2025-06-04
Last modified:2025-07-16
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy.
Cell Stem Cell, 32, 2025
3GHN
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BU of 3ghn by Molmil
Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A disintegrin and metalloproteinase with thrombospondin motifs 13, ...
Authors:Akiyama, M, Takeda, S, Kokame, K, Takagi, J, Miyata, T.
Deposit date:2009-03-04
Release date:2009-10-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
3GHM
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BU of 3ghm by Molmil
Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A disintegrin and metalloproteinase with thrombospondin motifs 13, ...
Authors:Akiyama, M, Takeda, S, Kokame, K, Takagi, J, Miyata, T.
Deposit date:2009-03-04
Release date:2009-10-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
1L0Q
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BU of 1l0q by Molmil
Tandem YVTN beta-propeller and PKD domains from an archaeal surface layer protein
Descriptor: Surface layer protein
Authors:Jing, H, Takagi, J, Liu, J.-H, Lindgren, S, Zhang, R.-G, Joachimiak, A, Wang, J.-H, Springer, T.A.
Deposit date:2002-02-12
Release date:2002-11-06
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Archaeal Surface Layer Proteins Contain beta Propeller, PKD, and beta Helix Domains and Are Related to Metazoan Cell Surface Proteins.
Structure, 10, 2002
8JYQ
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BU of 8jyq by Molmil
Crystal structure of cancer-specific anti-HER2 antibody H2Mab-214 in complex with epitope peptide
Descriptor: H2CasMab-1 VH(S112C),SARAH, H2CasMab-1 VL,SARAH(S37C), H2CasMab-1 epitope peptide
Authors:Arimori, T, Takagi, J.
Deposit date:2023-07-03
Release date:2024-03-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure, 32, 2024
8JYR
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BU of 8jyr by Molmil
Crystal structure of anti-HER2 antibody H2Mab-119 in complex with HER2 domain I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H2Mab-119 VH-CH1, H2Mab-119 light chain, ...
Authors:Arimori, T, Takagi, J.
Deposit date:2023-07-03
Release date:2024-03-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure, 32, 2024
5GKR
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BU of 5gkr by Molmil
Crystal structure of SLE patient-derived anti-DNA antibody in complex with oligonucleotide
Descriptor: DNA (5'-D(P*TP*TP*TP*T)-3'), IgG2, Fab (heavy chain), ...
Authors:Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J.
Deposit date:2016-07-05
Release date:2017-07-05
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus
Sci Rep, 7, 2017
5GKS
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BU of 5gks by Molmil
Crystal structure of SLE patient-derived anti-DNA antibody
Descriptor: IgG2, Fab (heavy chain), PHOSPHATE ION, ...
Authors:Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J.
Deposit date:2016-07-05
Release date:2017-07-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus
Sci Rep, 7, 2017
5GIR
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BU of 5gir by Molmil
Crystal structure of a Fab fragment with its ligand peptide
Descriptor: 1,2-ETHANEDIOL, Heavy chain of Fab fragment, LYS-PRO-ILE-ILE-ILE-GLY-SER-HIS-ALA-TYR-GLY-ASP, ...
Authors:Kitago, Y, Kaneko, K.K, Ogasawara, S, Kato, Y, Takagi, J.
Deposit date:2016-06-24
Release date:2016-09-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural basis for multi-specific peptide recognition by the anti-IDH1/2 monoclonal antibody, MsMab-1.
Biochem. Biophys. Res. Commun., 478, 2016
5GJE
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BU of 5gje by Molmil
Three-dimensional reconstruction of human LRP6 ectodomain complexed with Dkk1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Matoba, K, Mihara, E, Tamura-Kawakami, K, Hirai, H, Thompson, S, Iwasaki, K, Takagi, J.
Deposit date:2016-06-29
Release date:2017-01-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (21 Å)
Cite:Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1
Cell Rep, 18, 2017
3NKM
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BU of 3nkm by Molmil
Crystal structure of mouse autotaxin
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKN
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BU of 3nkn by Molmil
Crystal structure of mouse autotaxin in complex with 14:0-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
5GIS
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BU of 5gis by Molmil
Crystal structure of a Fab fragment with its ligand peptide
Descriptor: Heavy chain of Fab fragment, Light chain of Fab fragment, SULFATE ION, ...
Authors:Kitago, Y, Kaneko, K.K, Ogasawara, S, Kato, Y, Takagi, J.
Deposit date:2016-06-24
Release date:2016-09-14
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural basis for multi-specific peptide recognition by the anti-IDH1/2 monoclonal antibody, MsMab-1.
Biochem. Biophys. Res. Commun., 478, 2016
3NKO
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BU of 3nko by Molmil
Crystal structure of mouse autotaxin in complex with 16:0-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKQ
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BU of 3nkq by Molmil
Crystal structure of mouse autotaxin in complex with 18:3-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E,12Z,15Z)-octadeca-9,12,15-trienoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKP
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BU of 3nkp by Molmil
Crystal structure of mouse autotaxin in complex with 18:1-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKR
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BU of 3nkr by Molmil
Crystal structure of mouse autotaxin in complex with 22:6-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl (4Z,7E,10E,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.704 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
7XOM
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BU of 7xom by Molmil
Cryo-EM structure of occupied ring subunit 4 (OR4) of GroEL complexed with polyalanine model of UGT1A from GroEL-UGT1A double occupied ring complex
Descriptor: Chaperonin GroEL, Polyalanine model of UDP-glucuronosyltransferase 1A (UGT1A)
Authors:Stapleton, K, Takagi, J, Mizohata, E.
Deposit date:2022-05-01
Release date:2023-05-03
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM
To Be Published
7XOK
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BU of 7xok by Molmil
Cryo-EM structure of double occupied ring (DOR) of GroEL-UGT1A complex at 2.7 Ang. resolution
Descriptor: Chaperonin GroEL
Authors:Stapleton, K, Takagi, J, Mizohata, E.
Deposit date:2022-05-01
Release date:2023-05-03
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM
To Be Published
7XOJ
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BU of 7xoj by Molmil
Cryo-EM structure of GroEL bound to unfolded substrate (UGT1A) at 2.8 Ang. resolution (Consensus Refinement)
Descriptor: Chaperonin GroEL
Authors:Stapleton, K, Takagi, J, Mizohata, E.
Deposit date:2022-05-01
Release date:2023-05-03
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM
To Be Published
7XON
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BU of 7xon by Molmil
Cryo-EM structure of empty ring subunit 1 (ER1) from single empty ring of GroEL-UGT1A complex
Descriptor: Chaperonin GroEL
Authors:Stapleton, K, Takagi, J, Mizohata, E.
Deposit date:2022-05-01
Release date:2023-05-03
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM
To Be Published
7XOL
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BU of 7xol by Molmil
Cryo-EM structure of single empty ring 2 (SER2) of GroEL-UGT1A complex at 3.2 Ang. resolution
Descriptor: Chaperonin GroEL
Authors:Stapleton, K, Takagi, J, Mizohata, E.
Deposit date:2022-05-01
Release date:2023-05-03
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM
To Be Published

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