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4KTD
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BU of 4ktd by Molmil
Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE136, from non-human primate
Descriptor: GE136 Heavy Chain Fab, GE136 Light Chain Fab, GLYCEROL, ...
Authors:Poulsen, C, Tran, K, Standfield, R, Wyatt, R.T.
Deposit date:2013-05-20
Release date:2014-02-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign.
Proc.Natl.Acad.Sci.USA, 111, 2014
4KMT
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BU of 4kmt by Molmil
Crystal structure of human germline antibody 5-51/O12
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, SULFATE ION, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-05-08
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
4KQ4
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BU of 4kq4 by Molmil
Crystal structure of Anti-IL-17A antibody CNTO7357
Descriptor: CNTO7357 heavy chain, CNTO7357 light chain, NICKEL (II) ION
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-05-14
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
4MAU
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BU of 4mau by Molmil
Crystal structure of anti-ST2L antibody C2244
Descriptor: C2244 heavy chain, C2244 light chain, FORMIC ACID, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-08-16
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
4M6O
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BU of 4m6o by Molmil
Crystal structure of anti-NGF antibody CNTO7309
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CNTO7309 heavy chain, CNTO7309 light chain, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-08-09
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
4M7K
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BU of 4m7k by Molmil
Crystal structure of anti-tissue factor antibody 10H10
Descriptor: 10H10 heavy chain, 10H10 light chain, ACETATE ION, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-08-12
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
4M6M
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BU of 4m6m by Molmil
Crystal structure of anti-IL-23 antibody CNTO1959 at pH 9.5
Descriptor: CNTO1959 heavy chain, CNTO1959 light chain, DI(HYDROXYETHYL)ETHER, ...
Authors:Teplyakov, A, Obmolova, G, Gilliland, G.L.
Deposit date:2013-08-09
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
3BO8
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BU of 3bo8 by Molmil
The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Kumar, P, Vahedi-Faridi, A, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
Deposit date:2007-12-17
Release date:2008-12-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity
Protein Sci., 18, 2009
5SY8
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BU of 5sy8 by Molmil
Crystal structure of the complex of 10E8 Fab light chain mutant1 and T117v2 HIV-1 MPER scaffold
Descriptor: 10E8 EPITOPE SCAFFOLD T117v2, 10E8 FAB HEAVY CHAIN, 10E8 FAB LIGHT CHAIN, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2016-08-10
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5T5B
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BU of 5t5b by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF 10E8 FAB LIGHT CHAIN MUTANT5 AND T117V2 HIV-1 MPER SCAFFOLD
Descriptor: 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, Antibody 10E8 FAB LIGHT CHAIN MUTATED, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2016-08-30
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5T29
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BU of 5t29 by Molmil
Crystal structure of 10E8 Fab light chain mutant3, against the MPER region of the HIV-1 Env, in complex with the MPER epitope scaffold T117v2
Descriptor: 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, Antibody 10E8 FAB LIGHT CHAIN, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2016-08-23
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5T6L
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BU of 5t6l by Molmil
Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2
Descriptor: 10E8 EPITOPE SCAFFOLD T117V2, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Antibody 10E8 FAB HEAVY CHAIN, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2016-09-01
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5T80
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BU of 5t80 by Molmil
Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 and phosphatidic acid (06:0 PA)
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2016-09-06
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5TFW
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BU of 5tfw by Molmil
Crystal structure of 10E8 Fab light chain mutant2 against the MPER region of the HIV-1 Env, in complex with T117v2 epitope scaffold
Descriptor: 1,2-ETHANEDIOL, 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2016-09-26
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.168 Å)
Cite:Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5T85
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BU of 5t85 by Molmil
Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 and phosphatidylglycerol (06:0 PG)
Descriptor: (2S)-3-{[(R)-{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2016-09-06
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.373 Å)
Cite:Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5VN3
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BU of 5vn3 by Molmil
Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding variable domain of 17b
Descriptor: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ozorowski, G, Pallesen, J, Ward, A.B.
Deposit date:2017-04-28
Release date:2017-07-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.
Nature, 547, 2017
5VN8
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BU of 5vn8 by Molmil
Cryo-EM model of B41 SOSIP.664 in complex with fragment antigen binding variable domain of b12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Ozorowski, G, Pallesen, J, Ward, A.B, Cottrell, C.A.
Deposit date:2017-04-28
Release date:2017-07-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.
Nature, 547, 2017
5W3Q
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BU of 5w3q by Molmil
L28F E.coli DHFR in complex with NADPH
Descriptor: CALCIUM ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Oyen, D, Wright, P.E, Wilson, I.A.
Deposit date:2017-06-08
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion.
J. Am. Chem. Soc., 139, 2017
1ITH
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BU of 1ith by Molmil
STRUCTURE DETERMINATION AND REFINEMENT OF HOMOTETRAMERIC HEMOGLOBIN FROM URECHIS CAUPO AT 2.5 ANGSTROMS RESOLUTION
Descriptor: CYANIDE ION, HEMOGLOBIN (CYANO MET), PROTOPORPHYRIN IX CONTAINING FE
Authors:Hackert, M, Kolatkar, P, Ernst, S.R, Ogata, C.M, Hendrickson, W.A, Merritt, E.A, Phizackerley, R.P.
Deposit date:1991-12-03
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure determination and refinement of homotetrameric hemoglobin from Urechis caupo at 2.5 A resolution.
Acta Crystallogr.,Sect.B, 48, 1992
1KB5
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BU of 1kb5 by Molmil
MURINE T-CELL RECEPTOR VARIABLE DOMAIN/FAB COMPLEX
Descriptor: ANTIBODY DESIRE-1, KB5-C20 T-CELL ANTIGEN RECEPTOR
Authors:Housset, D, Mazza, G, Gregoire, C, Piras, C, Malissen, B, Fontecilla-Camps, J.C.
Deposit date:1997-04-06
Release date:1998-04-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain.
EMBO J., 16, 1997
2CKB
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BU of 2ckb by Molmil
STRUCTURE OF THE 2C/KB/DEV8 COMPLEX
Descriptor: ALPHA, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ...
Authors:Garcia, K.C, Degano, M, Wilson, I.A.
Deposit date:1998-01-14
Release date:1998-04-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen.
Science, 279, 1998
2FX9
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BU of 2fx9 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41
Descriptor: Fab 4E10, Fragment of HIV glycoprotein gp41
Authors:Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
Deposit date:2006-02-03
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
2FX8
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BU of 2fx8 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with an aib-induced peptide encompassing the 4e10 epitope on gp41
Descriptor: Fab 4E10, Fragment of HIV glycoprotein (GP41)
Authors:Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
Deposit date:2006-02-03
Release date:2006-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
2FX7
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BU of 2fx7 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a 16-residue peptide encompassing the 4e10 epitope on gp41
Descriptor: Fab 4E10, Fragment of HIV glycoprotein (GP41), GLYCEROL
Authors:Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
Deposit date:2006-02-03
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007

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