5W3Q

L28F E.coli DHFR in complex with NADPH

Summary for 5W3Q

Entry DOI	10.2210/pdb5w3q/pdb
Descriptor	Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ... (4 entities in total)
Functional Keywords	oxidoreductase
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	1
Total formula weight	18838.86
Authors	Oyen, D.,Wright, P.E.,Wilson, I.A. (deposition date: 2017-06-08, release date: 2017-08-09, Last modification date: 2023-10-04)
Primary citation	Oyen, D.,Fenwick, R.B.,Aoto, P.C.,Stanfield, R.L.,Wilson, I.A.,Dyson, H.J.,Wright, P.E. Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion. J. Am. Chem. Soc., 139:11233-11240, 2017 Cited by PubMed: 28737940 DOI: 10.1021/jacs.7b05958 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.401 Å)

Structure validation