2QCY
 
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7LO7
 | | NorA in complex with Fab25 | | 分子名称: | Fab25 Heavy Chain, Fab25 Light Chain, Quinolone resistance protein NorA | | 著者 | Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N. | | 登録日 | 2021-02-09 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat.Chem.Biol., 18, 2022
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7LO8
 | | NorA in complex with Fab36 | | 分子名称: | Fab36 Heavy Chain, Fab36 Light Chain, Quinolone resistance protein NorA | | 著者 | Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N. | | 登録日 | 2021-02-09 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat.Chem.Biol., 18, 2022
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3GXU
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8ETM
 | | Human triacylglycerol synthesizing enzyme DGAT1 in complex with DGAT1IN1 inhibitor | | 分子名称: | Diacylglycerol O-acyltransferase 1, [(1S,4r)-4-{4-[(4S)-2-({[4-(trifluoromethoxy)phenyl]methyl}carbamoyl)imidazo[1,2-a]pyridin-6-yl]phenyl}cyclohexyl]acetic acid | | 著者 | Sui, X, Kun, W, Walther, T, Farese, R, Liao, M. | | 登録日 | 2022-10-17 | | 公開日 | 2023-06-07 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
Nat Commun, 14, 2023
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8ESM
 | | Human triacylglycerol synthesizing enzyme DGAT1 in complex with T863 inhibitor | | 分子名称: | Diacylglycerol O-acyltransferase 1, {(1r,4r)-4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl}acetic acid | | 著者 | Sui, X, Kun, W, Walther, T, Farese, R, Liao, M. | | 登録日 | 2022-10-14 | | 公開日 | 2023-06-07 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
Nat Commun, 14, 2023
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6JO7
 | | Crystal structure of mouse MXRA8 | | 分子名称: | Matrix remodeling-associated protein 8 | | 著者 | Song, H, Zhao, Z, Qi, J, Gao, F, Gao, G.F. | | 登録日 | 2019-03-20 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein.
Cell, 177, 2019
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6JO8
 | | The complex structure of CHIKV envelope glycoprotein bound to human MXRA8 | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHIKV E1, ... | | 著者 | Song, H, Zhao, Z, Qi, J, Gao, F, Gao, F.G. | | 登録日 | 2019-03-20 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.495 Å) | | 主引用文献 | Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein.
Cell, 177, 2019
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6WU1
 | | Structure of apo LaINDY | | 分子名称: | DASS family sodium-coupled anion symporter, DECANE, HEXANE, ... | | 著者 | Sauer, D.B, Marden, J.J, Cocco, N.C, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | 登録日 | 2020-05-04 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
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6WU2
 | | Structure of the LaINDY-malate complex | | 分子名称: | DASS family sodium-coupled anion symporter, DECANE, HEXANE, ... | | 著者 | Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | 登録日 | 2020-05-04 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
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6WCZ
 | | CryoEM structure of full-length ZIKV NS5-hSTAT2 complex | | 分子名称: | Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION | | 著者 | Boxiao, W, Stephanie, T, Kang, Z, Maria, T.S, Jian, F, Jiuwei, L, Linfeng, G, Wendan, R, Yanxiang, C, Ethan, C.V, HeaJin, H, Matthew, J.E, Sean, E.O, Adolfo, G.S, Hong, Z, Rong, H, Jikui, S. | | 登録日 | 2020-03-31 | | 公開日 | 2020-07-08 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis for STAT2 suppression by flavivirus NS5.
Nat.Struct.Mol.Biol., 27, 2020
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6WTW
 | | Structure of LaINDY crystallized in the presence of alpha-ketoglutarate and malate | | 分子名称: | DASS family sodium-coupled anion symporter | | 著者 | Sauer, D.B, Cocco, N, Marden, J.J, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | 登録日 | 2020-05-04 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
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6WU4
 | | Structure of the LaINDY-alpha-ketoglutarate complex | | 分子名称: | DASS family sodium-coupled anion symporter | | 著者 | Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | 登録日 | 2020-05-04 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
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6WU3
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7C01
 | | Molecular basis for a potent human neutralizing antibody targeting SARS-CoV-2 RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CB6 heavy chain, CB6 light chain, ... | | 著者 | Shi, R, Qi, J, Wang, Q, Gao, F.G, Yan, J. | | 登録日 | 2020-04-29 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2.
Nature, 584, 2020
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3CKH
 | | Crystal structure of Eph A4 receptor | | 分子名称: | Ephrin type-A receptor 4 | | 著者 | Shi, J.H, Song, J.X. | | 登録日 | 2008-03-15 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor.
J.Biol.Chem., 283, 2008
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1VJI
 | | Gene Product of At1g76680 from Arabidopsis thaliana | | 分子名称: | 12-oxophytodienoate reductase (OPR1), FLAVIN MONONUCLEOTIDE | | 著者 | Wesenberg, G.E, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2004-02-24 | | 公開日 | 2004-03-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | | 主引用文献 | X-ray structure of Arabidopsis At1g77680, 12-oxophytodienoate reductase isoform 1.
Proteins, 61, 2005
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7T9G
 | | Structure of VcINDY-Na+ | | 分子名称: | DASS family sodium-coupled anion symporter, SODIUM ION | | 著者 | Sauer, D.B, Marden, J.J, Song, J.M, Wang, D.N. | | 登録日 | 2021-12-19 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | Structural basis of ion - substrate coupling in the Na + -dependent dicarboxylate transporter VcINDY.
Nat Commun, 13, 2022
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7T9F
 | | Structure of VcINDY-apo | | 分子名称: | DASS family sodium-coupled anion symporter | | 著者 | Sauer, D.B, Marden, J.J, Song, J.M, Wang, D.N. | | 登録日 | 2021-12-19 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Structural basis of ion - substrate coupling in the Na + -dependent dicarboxylate transporter VcINDY.
Nat Commun, 13, 2022
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3FHQ
 | | Structure of endo-beta-N-acetylglucosaminidase A | | 分子名称: | 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, Endo-beta-N-acetylglucosaminidase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose | | 著者 | Jie, Y, Li, L, Shaw, N, Li, Y, Song, J, Zhang, W, Xia, C, Zhang, R, Joachimiak, A, Zhang, H.-C, Wang, L.-X, Wang, P, Liu, Z.-J. | | 登録日 | 2008-12-10 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.452 Å) | | 主引用文献 | Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A
Plos One, 4, 2009
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8WRJ
 | | glycosyltransferase UGT74AN3 | | 分子名称: | 5-[(1R,2S,4R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-6-yl]pyran-2-one, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE | | 著者 | Huang, W, Long, F. | | 登録日 | 2023-10-15 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3
Acs Catalysis, 14, 2024
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8WRK
 | | glycosyltransferase UGT74AN3 | | 分子名称: | Glycosyltransferase, PICEATANNOL, URIDINE-5'-DIPHOSPHATE | | 著者 | Huang, W, Long, F. | | 登録日 | 2023-10-15 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3
Acs Catalysis, 14, 2024
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3SXN
 | | Mycobacterium tuberculosis Eis protein initiates modulation of host immune responses by acetylation of DUSP16/MKP-7 | | 分子名称: | COENZYME A, Enhanced intracellular survival protein | | 著者 | Kim, K.H, An, D.R, Yoon, J.Y, Kim, H.S, Yoon, H.J, Song, J.S, Im, H.N, Kim, J, Kim, D.J, Lee, S.J, Kim, H.J, Lee, J.Y, Suh, S.W. | | 登録日 | 2011-07-15 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Mycobacterium tuberculosis Eis protein initiates suppression of host immune responses by acetylation of DUSP16/MKP-7
Proc.Natl.Acad.Sci.USA, 109, 2012
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5KBW
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5KC0
 | | Crystal structure of TmRibU, hexagonal crystal form | | 分子名称: | RIBOFLAVIN, Riboflavin transporter RibU, nonyl beta-D-glucopyranoside | | 著者 | Karpowich, N.K, Wang, D.N, Song, J.M. | | 登録日 | 2016-06-03 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.2001 Å) | | 主引用文献 | An Aromatic Cap Seals the Substrate Binding Site in an ECF-Type S Subunit for Riboflavin.
J.Mol.Biol., 428, 2016
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