4JQI
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![BU of 4jqi by Molmil](/molmil-images/mine/4jqi) | Structure of active beta-arrestin1 bound to a G protein-coupled receptor phosphopeptide | Descriptor: | 1,2-ETHANEDIOL, Beta-arrestin-1, CHLORIDE ION, ... | Authors: | Shukla, A.K, Manglik, A, Kruse, A.C, Xiao, K, Reis, R.I, Tseng, W.C, Staus, D.P, Hilger, D, Uysal, S, Huang, L.H, Paduch, M, Shukla, P.T, Koide, A, Koide, S, Weis, W.I, Kossiakoff, A.A, Kobilka, B.K, Lefkowitz, R.J. | Deposit date: | 2013-03-20 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature, 497, 2013
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8JZZ
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![BU of 8jzz by Molmil](/molmil-images/mine/8jzz) | Structure of human C5a-desArg bound human C5aR1 in complex with Go | Descriptor: | Antibody fragment ScFv16, C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-07-06 | Release date: | 2023-10-18 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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8J6D
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![BU of 8j6d by Molmil](/molmil-images/mine/8j6d) | Structure of EP141-C3aR-Go complex | Descriptor: | Antibody fragment - ScFv16, C3a anaphylatoxin chemotactic receptor, EP141 peptide agonist, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-04-25 | Release date: | 2023-10-18 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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8J8Z
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![BU of 8j8z by Molmil](/molmil-images/mine/8j8z) | Structure of beta-arrestin1 in complex with D6Rpp | Descriptor: | Atypical chemokine receptor 2, Beta-arrestin-1, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-02 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8J8V
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![BU of 8j8v by Molmil](/molmil-images/mine/8j8v) | Structure of beta-arrestin2 in complex with D6Rpp (Local Refine) | Descriptor: | Atypical chemokine receptor 2, Beta-arrestin-2, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-02 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8J97
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![BU of 8j97 by Molmil](/molmil-images/mine/8j97) | Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local refine, cross-linked) | Descriptor: | Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K. | Deposit date: | 2023-05-02 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8JAF
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![BU of 8jaf by Molmil](/molmil-images/mine/8jaf) | Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local Refine, non-cross linked) | Descriptor: | Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ... | Authors: | Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K. | Deposit date: | 2023-05-05 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8JA3
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![BU of 8ja3 by Molmil](/molmil-images/mine/8ja3) | Structure of beta-arrestin1 in complex with C3aRpp | Descriptor: | Beta-arrestin-1, C3a anaphylatoxin chemotactic receptor, Fab30 heavy chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-05 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8J9K
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![BU of 8j9k by Molmil](/molmil-images/mine/8j9k) | Structure of basal beta-arrestin2 | Descriptor: | Beta-arrestin-2, Fab6 heavy chain, Fab6 light chain | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-03 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8J8R
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![BU of 8j8r by Molmil](/molmil-images/mine/8j8r) | Structure of beta-arrestin2 in complex with M2Rpp | Descriptor: | Beta-arrestin-2, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K. | Deposit date: | 2023-05-02 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8JHN
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![BU of 8jhn by Molmil](/molmil-images/mine/8jhn) | Structure of MMF-GPR109A-G protein complex | Descriptor: | (E)-4-methoxy-4-oxidanylidene-but-2-enoic acid, G protein subunit alpha o1,Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-24 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. Nat Commun, 15, 2024
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8IYH
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![BU of 8iyh by Molmil](/molmil-images/mine/8iyh) | Structure of MK6892-GPR109A-G-protein complex | Descriptor: | 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-04-04 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. Nat Commun, 15, 2024
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8IYW
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![BU of 8iyw by Molmil](/molmil-images/mine/8iyw) | Structure of GSK256073-GPR109A-G-protein complex | Descriptor: | 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-04-06 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. Nat Commun, 15, 2024
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8IY9
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![BU of 8iy9 by Molmil](/molmil-images/mine/8iy9) | Structure of Niacin-GPR109A-G protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | Authors: | Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-04-04 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. Nat Commun, 15, 2024
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8JER
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![BU of 8jer by Molmil](/molmil-images/mine/8jer) | Structure of Acipimox-GPR109A-G protein complex | Descriptor: | 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-16 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. Nat Commun, 15, 2024
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8GOC
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![BU of 8goc by Molmil](/molmil-images/mine/8goc) | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Vasopressin V2 receptor, V2R | Descriptor: | Beta-arrestin-2, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-24 | Release date: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Structure of beta-arrestin in complex with a phosphopeptide Mol.Cell, 2023
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8GO8
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![BU of 8go8 by Molmil](/molmil-images/mine/8go8) | Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C5a anaphylatoxin chemotactic receptor 1, C5aR1 | Descriptor: | Beta-arrestin-1, C5a anaphylatoxin chemotactic receptor 1, Fab30 heavy chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-24 | Release date: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structure of beta-arrestin in complex with a phosphopeptide Mol.Cell, 2023
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8GP3
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![BU of 8gp3 by Molmil](/molmil-images/mine/8gp3) | Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C-X-C chemokine receptor type 4, CXCR4 | Descriptor: | Beta-arrestin-1, C-X-C chemokine receptor type 4, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-25 | Release date: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure of beta-arrestin in complex with a phosphopeptide Mol.Cell, 2023
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8GOO
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![BU of 8goo by Molmil](/molmil-images/mine/8goo) | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human C5a anaphylatoxin chemotactic receptor 1, C5aR1 | Descriptor: | Beta-arrestin-2, C5a anaphylatoxin chemotactic receptor 1, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-25 | Release date: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structure of beta-arrestin in complex with a phosphopeptide Mol.Cell, 2023
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8GO9
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![BU of 8go9 by Molmil](/molmil-images/mine/8go9) | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Atypical chemokine receptor 2, ACKR2 (D6R) | Descriptor: | Atypical chemokine receptor 2, Beta-arrestin-2, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-24 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8HPT
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![BU of 8hpt by Molmil](/molmil-images/mine/8hpt) | Structure of C5a-pep bound mouse C5aR1 in complex with Go | Descriptor: | Antibody fragment ScFv16, C5a anaphylatoxin chemotactic receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Saha, S, Maharana, J, Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-12-13 | Release date: | 2023-10-18 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structure of a GPCR-G protein in complex with a synthetic peptide agonist Cell(Cambridge,Mass.), 2023
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8I0Z
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![BU of 8i0z by Molmil](/molmil-images/mine/8i0z) | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human C5a anaphylatoxin chemotactic receptor 1, C5aR1 (Local refine) | Descriptor: | Beta-arrestin-2, C5a anaphylatoxin chemotactic receptor 1, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-01-12 | Release date: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (4.33 Å) | Cite: | Structure of beta-arrestin in complex with a phosphopeptide Mol.Cell, 2023
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8HQC
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![BU of 8hqc by Molmil](/molmil-images/mine/8hqc) | Structure of a GPCR-G protein in complex with a natural peptide agonist | Descriptor: | Antibody fragment, C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, ... | Authors: | Saha, S, Maharana, J, Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-12-13 | Release date: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Structure of a GPCR-G protein in complex with a synthetic peptide agonist Cell(Cambridge,Mass.), 2023
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8I0Q
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![BU of 8i0q by Molmil](/molmil-images/mine/8i0q) | Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C-X-C chemokine receptor type 4, CXCR4 (Local refine) | Descriptor: | Beta-arrestin-1, C-X-C chemokine receptor type 4, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-01-11 | Release date: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (4.45 Å) | Cite: | Structure of beta-arrestin in complex with a phosphopeptide Mol.Cell, 2023
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8I10
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![BU of 8i10 by Molmil](/molmil-images/mine/8i10) | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Vasopressin V2 receptor, V2R (Local refine) | Descriptor: | Beta-arrestin-2, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-01-12 | Release date: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Structure of beta-arrestin in complex with a phosphopeptide Mol.Cell, 2023
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