8J97

Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local refine, cross-linked)

Summary for 8J97

• Entry DOI: 10.2210/pdb8j97/pdb
• EMDB information: 36090
• Descriptor: Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ... (4 entities in total)
• Functional Keywords: gpcr, arrestin, signaling protein, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Bos taurus (cattle); More
• Total number of polymer chains: 4
• Total formula weight: 65245.59

Authors

Maharana, J.,Sano, F.K.,Shihoya, W.,Banerjee, R.,Nureki, O.,Shukla, A.K. (deposition date: 2023-05-02, release date: 2023-12-27, Last modification date: 2024-01-17)

• Primary citation: Maharana, J.,Sano, F.K.,Sarma, P.,Yadav, M.K.,Duan, L.,Stepniewski, T.M.,Chaturvedi, M.,Ranjan, A.,Singh, V.,Saha, S.,Mahajan, G.,Chami, M.,Shihoya, W.,Selent, J.,Chung, K.Y.,Banerjee, R.,Nureki, O.,Shukla, A.K.; Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors.; Science, 383:101-108, 2024; PubMed: 38175886; DOI: 10.1126/science.adj3347

Experimental method

ELECTRON MICROSCOPY (3.2 Å)