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1OW1
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BU of 1ow1 by Molmil
Crystal structure of the SPOC domain of the human transcriptional corepressor, SHARP.
分子名称: SMART/HDAC1 associated repressor protein
著者Schwabe, J.W, Ariyoshi, M.
登録日2003-03-28
公開日2003-08-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signaling
Genes Dev., 17, 2003
4AA6
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BU of 4aa6 by Molmil
The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation
分子名称: 5'-D(*CP*TP*AP*AP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP *CP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP *CP*TP*TP*A)-3', ESTROGEN RECEPTOR, ...
著者Schwabe, J.W, Chapman, L, Rhodes, D.
登録日2011-11-30
公開日2011-12-14
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation.
Structure, 3, 1995
1HCQ
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BU of 1hcq by Molmil
THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
分子名称: DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP*CP*CP*T P*G)-3'), DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (ESTROGEN RECEPTOR), ...
著者Schwabe, J.W.R, Chapman, L, Finch, J.T, Rhodes, D.
登録日1995-01-04
公開日1995-11-23
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements.
Cell(Cambridge,Mass.), 75, 1993
1HCP
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BU of 1hcp by Molmil
DNA RECOGNITION BY THE OESTROGEN RECEPTOR: FROM SOLUTION TO THE CRYSTAL
分子名称: HUMAN/CHICKEN ESTROGEN RECEPTOR, ZINC ION
著者Schwabe, J.W.R, Rhodes, D, Neuhaus, D.
登録日1993-11-23
公開日1995-11-23
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献DNA recognition by the oestrogen receptor: from solution to the crystal.
Structure, 1, 1993
5ICN
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BU of 5icn by Molmil
HDAC1:MTA1 in complex with inositol-6-phosphate and a novel peptide inhibitor based on histone H4
分子名称: GLY-ALA-6A0-ARG-HIS, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Millard, C.J, Robertson, N.S, Watson, P.J, Jameson, A.G, Schwabe, J.W.R.
登録日2016-02-23
公開日2016-05-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.
Nat Commun, 7, 2016
5FXY
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BU of 5fxy by Molmil
Structure of the human RBBP4:MTA1(464-546) complex
分子名称: HISTONE-BINDING PROTEIN RBBP4, METASTASIS-ASSOCIATED PROTEIN MTA1
著者Millard, C.J, Varma, N, Fairall, L, Schwabe, J.W.R.
登録日2016-03-03
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The structure of the core NuRD repression complex provides insights into its interaction with chromatin.
Elife, 5, 2016
8AU4
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BU of 8au4 by Molmil
Structural insights reveal a heterotetramer between oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
分子名称: Ral guanine nucleotide dissociation stimulator-like 2
著者Tariq, M, Ikeya, T, Togashi, N, Fairall, L, Alejo, C.B, Kamei, S, Alonso, B.R, Campillo, M.A.M, Hudson, A, Ito, Y, Schwabe, J, Dominguez, C, Tanaka, K.
登録日2022-08-25
公開日2023-08-23
最終更新日2023-10-25
実験手法SOLUTION NMR
主引用文献Structural insights into the complex of oncogenic KRas4B G12V and Rgl2, a RalA/B activator.
Life Sci Alliance, 7, 2024
8B69
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BU of 8b69 by Molmil
Heterotetramer of K-Ras4B(G12V) and Rgl2(RBD)
分子名称: Isoform 2B of GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Tariq, M, Fairall, L, Romartinez-Alonso, B, Dominguez, C, Schwabe, J.W.R, Tanaka, K.
登録日2022-09-26
公開日2023-08-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Structural insights into the complex of oncogenic KRas4B G12V and Rgl2, a RalA/B activator.
Life Sci Alliance, 7, 2024
2MWI
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BU of 2mwi by Molmil
The structure of the carboxy-terminal domain of DNTTIP1
分子名称: Deoxynucleotidyltransferase terminal-interacting protein 1
著者Schwabe, J.W.R, Muskett, F.W, Itoh, T.
登録日2014-11-11
公開日2015-02-18
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.
Nucleic Acids Res., 43, 2015
1ZFD
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BU of 1zfd by Molmil
SWI5 ZINC FINGER DOMAIN 2, NMR, 45 STRUCTURES
分子名称: SWI5, ZINC ION
著者Neuhaus, D, Nakaseko, Y, Schwabe, J.W.R, Rhodes, D, Klug, A.
登録日1996-04-04
公開日1996-10-14
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structures of two zinc-finger domains from SWI5 obtained using two-dimensional 1H nuclear magnetic resonance spectroscopy. A zinc-finger structure with a third strand of beta-sheet.
J.Mol.Biol., 228, 1992
2DRP
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BU of 2drp by Molmil
THE CRYSTAL STRUCTURE OF A TWO ZINC-FINGER PEPTIDE REVEALS AN EXTENSION TO THE RULES FOR ZINC-FINGER/DNA RECOGNITION
分子名称: DNA (5'-D(*CP*TP*AP*AP*TP*AP*AP*GP*GP*AP*TP*AP*AP*CP*GP*TP*C P*CP*G)-3'), DNA (5'-D(*TP*CP*GP*GP*AP*CP*GP*TP*TP*AP*TP*CP*CP*TP*TP*AP*T P*TP*A)-3'), PROTEIN (TRAMTRACK DNA-BINDING DOMAIN), ...
著者Fairall, L, Schwabe, J.W.R, Chapman, L, Finch, J.T, Rhodes, D.
登録日1994-06-06
公開日1994-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition.
Nature, 366, 1993
2L5G
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BU of 2l5g by Molmil
Co-ordinates and 1H, 13C and 15N chemical shift assignments for the complex of GPS2 53-90 and SMRT 167-207
分子名称: G protein pathway suppressor 2, Putative uncharacterized protein NCOR2
著者Oberoi, J, Yang, J, Neuhaus, D, Schwabe, J.W.R.
登録日2010-11-01
公開日2011-02-02
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.
Nat.Struct.Mol.Biol., 18, 2011
6G16
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BU of 6g16 by Molmil
Structure of the human RBBP4:MTA1(464-546) complex showing loop exchange
分子名称: Histone-binding protein RBBP4, Metastasis-associated protein MTA1
著者Millard, C.J, Varma, N, Fairall, L, Schwabe, J.W.R.
登録日2018-03-20
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structure of the core NuRD repression complex provides insights into its interaction with chromatin.
Elife, 5, 2016
2YHO
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BU of 2yho by Molmil
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
分子名称: ACETATE ION, E3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ...
著者Fairall, L, Goult, B.T, Millard, C.J, Tontonoz, P, Schwabe, J.W.R.
登録日2011-05-04
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
1NCS
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BU of 1ncs by Molmil
NMR STUDY OF SWI5 ZINC FINGER DOMAIN 1
分子名称: TRANSCRIPTIONAL FACTOR SWI5, ZINC ION
著者Dutnall, R.N, Neuhaus, D, Rhodes, D.
登録日1996-02-26
公開日1996-06-10
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献The solution structure of the first zinc finger domain of SWI5: a novel structural extension to a common fold.
Structure, 4, 1996
1MEY
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BU of 1mey by Molmil
CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA
分子名称: CHLORIDE ION, CONSENSUS ZINC FINGER, DNA (5'-D(*AP*TP*GP*AP*GP*GP*CP*AP*GP*AP*AP*CP*T)-3'), ...
著者Kim, C.A, Berg, J.M.
登録日1996-09-27
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A 2.2 A Resolution Crystal Structure of a Designed Zinc Finger Protein Bound to DNA
Nat.Struct.Biol., 3, 1996

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